St. Louis Cardinals vs Detroit Tigers Prediction & Picks - MLB

USA - MLB

St. Louis Cardinals
5/20/25 19:45
Detroit Tigers

Prediction:

 

Over 7.5

 

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Erik Gibbs | in MLB Picks

The Detroit Tigers and St. Louis Cardinals continue their three-game set on Tuesday after St. Louis opened the series with an emphatic 11-4 win on Monday. Despite that setback, Detroit remains one of the top-performing teams in the American League this season, boasting a 31-16 overall record.

Prior to the series opener, the Tigers had rattled off five straight wins, including a tight one-run victory over the Toronto Blue Jays. Offensively, Detroit has been consistent, carrying a .260 team batting average and generating 253 runs on 418 hits so far this year. Their pitching staff has also been exceptional, with a combined team ERA of 3.21—among the best in the league.

The Cardinals, meanwhile, are six games over .500 and have shown flashes of strong form, though they've dropped two of their last five outings. Their recent loss to the Kansas City Royals snapped a three-game win streak. Offensively, the Cardinals are nearly neck-and-neck with Detroit, batting .262 as a team while recording 224 runs on 421 hits. They’ve also flashed some pop with 45 home runs and a team slugging percentage of .404.

St. Louis Cardinals vs Detroit Tigers Form

Table

Teams Pts P W L
11 Detroit Tigers
0.537 162 87 75
20 St. Louis Cardinals
0.481 162 78 84

St. Louis Cardinals and Detroit Tigers Latest Matches

St. Louis Cardinals
St. Louis Cardinals Latest matches
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 18, 2025 - MLB

Kansas City Royals
2 :  1
St. Louis Cardinals

May 17, 2025 - MLB

Kansas City Royals
0 :  1
St. Louis Cardinals

May 16, 2025 - MLB

Kansas City Royals
3 :  10
St. Louis Cardinals

May 12, 2025 - MLB

Philadelphia Phillies
2 :  3
St. Louis Cardinals

May 10, 2025 - MLB

Washington Nationals
2 :  4
St. Louis Cardinals

May 7, 2025 - MLB

St. Louis Cardinals
5 :  0
Pittsburgh Pirates
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 7, 2025 - MLB

St. Louis Cardinals
5 :  0
Pittsburgh Pirates

May 6, 2025 - MLB

St. Louis Cardinals
2 :  1
Pittsburgh Pirates

May 2, 2025 - MLB

St. Louis Cardinals
3 :  9
New York Mets

Apr 26, 2025 - MLB

St. Louis Cardinals
6 :  5
Milwaukee Brewers

Apr 16, 2025 - MLB

St. Louis Cardinals
4 :  1
Houston Astros

Apr 15, 2025 - MLB

St. Louis Cardinals
0 :  2
Houston Astros
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 18, 2025 - MLB

Kansas City Royals
2 :  1
St. Louis Cardinals

May 17, 2025 - MLB

Kansas City Royals
0 :  1
St. Louis Cardinals

May 16, 2025 - MLB

Kansas City Royals
3 :  10
St. Louis Cardinals

May 12, 2025 - MLB

Philadelphia Phillies
2 :  3
St. Louis Cardinals

May 10, 2025 - MLB

Washington Nationals
2 :  4
St. Louis Cardinals

May 1, 2025 - MLB

Cincinnati Reds
9 :  1
St. Louis Cardinals
Detroit Tigers
Detroit Tigers Latest matches
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 14, 2025 - MLB

Detroit Tigers
6 :  5
Boston Red Sox

May 9, 2025 - MLB

Detroit Tigers
2 :  1
Texas Rangers

May 2, 2025 - MLB

Los Angeles Angels
1 :  9
Detroit Tigers

May 1, 2025 - MLB

Los Angeles Angels
4 :  10
Detroit Tigers

Apr 30, 2025 - MLB

Houston Astros
4 :  7
Detroit Tigers

Apr 29, 2025 - MLB

Houston Astros
6 :  4
Detroit Tigers
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 14, 2025 - MLB

Detroit Tigers
6 :  5
Boston Red Sox

May 9, 2025 - MLB

Detroit Tigers
2 :  1
Texas Rangers

Apr 27, 2025 - MLB

Detroit Tigers
7 :  0
Baltimore Orioles

Apr 26, 2025 - MLB

Detroit Tigers
4 :  3
Baltimore Orioles

Apr 23, 2025 - MLB

Detroit Tigers
6 :  0
San Diego Padres

Apr 22, 2025 - MLB

Detroit Tigers
0 :  2
San Diego Padres
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 2, 2025 - MLB

Los Angeles Angels
1 :  9
Detroit Tigers

May 1, 2025 - MLB

Los Angeles Angels
4 :  10
Detroit Tigers

Apr 30, 2025 - MLB

Houston Astros
4 :  7
Detroit Tigers

Apr 29, 2025 - MLB

Houston Astros
6 :  4
Detroit Tigers

Apr 28, 2025 - MLB

Houston Astros
8 :  5
Detroit Tigers

Apr 16, 2025 - MLB

Milwaukee Brewers
5 :  1
Detroit Tigers

St. Louis Cardinals against Detroit Tigers : Head to Head (H2H)

St. Louis Cardinals

0 %

Detroit Tigers

100 %

Apr 30, 2024 - MLB

Detroit Tigers
11 :  6
St. Louis Cardinals

St. Louis Cardinals - Detroit Tigers Key Points

  1. The Tigers are 5-1 SU in their last 6 games.
  2. The Tigers are 8-3 SU in their last 11 games vs. the Cardinals
  3. The Over is 13-6 in the Tigers' last 19 games
  4. The Cardinals are 12-2 SU in their last 14 games

Our St. Louis Cardinals vs Detroit Tigers Prediction

Taking the mound for Detroit on Tuesday is Tarik Skubal, the reigning AL Cy Young Award winner. The 28-year-old lefty will be making his 10th start of the season and enters with a 4-2 record. Detroit has come out on top in each of his last four outings, underscoring both his consistency and the team’s confidence when he’s on the mound.

St. Louis counters with Erick Fedde, a 32-year-old right-hander also making his 10th start of the season. Fedde holds a 3-3 record and carries a 3.44 ERA, with 32 strikeouts and 25 walks. However, he’s struggled recently, allowing seven runs against Milwaukee and three more against the Mets in recent appearances.

Adding to Detroit’s advantage is the power threat in their lineup. Hitters like Spencer Torkelson, Riley Greene, and Kerry Carpenter have each tallied more home runs than any single player on the Cardinals roster. With Skubal on the mound and more offensive firepower, Detroit appears poised to bounce back from Monday’s defeat and even the series. Our prediction for St. Louis Cardinals vs. Detroit Tigers: Tigers to win.

Prediction:

 

Over 7.5

 

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

St. Louis Cardinals vs Detroit Tigers Picks