Chicago Cubs vs Detroit Tigers Prediction & Picks - MLB

USA - MLB

Chicago Cubs
7/22/26 20:10
Detroit Tigers

Prediction:

 

UNDER 8

-115
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 by Travis Pulver in MLB Picks

The Chicago Cubs (57-44, 30-21 Home) will go for the series win against the Detroit Tigers (47-54, 20-31 Away) at Wrigley Field in the Windy City, starting at 8 p.m. EST. Fans can catch the game on ESPN.

Detroit needed extra innings to get the win Monday, but secured an 8-6 victory with three runs in the tenth. But the Cubbies flexed a little muscle at the plate in the first yesterday, scoring six in the bottom half of the inning before going on to win 11-2.

The Cubs are turning to Colin Rea to start the game today. Rea is 7-6 in 20 appearances (16 starts) with a 4.74 ERA and a 1.42 WHIP. But he has had his better stuff at home, where he is 3-2 with a save in nine appearances (eight starts) with a 2.94 ERA and a .242 OBA.

As for the Tigers, Detroit is expected to hand the ball to Keider Montero. Montero is 6-5 in 21 appearances (15 starts) with a 3.22 ERA and a 0.98 WHIP. He often has his best stuff on the road, where he is 2-2 with one save in eight appearances (four starts), a 2.59 ERA, and a .153 OBA.

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Chicago Cubs vs Detroit Tigers Form

Table

Teams Pts P W L
5 Chicago Cubs
0.564 101 57 44
22 Detroit Tigers
0.465 101 47 54

Chicago Cubs and Detroit Tigers Latest Matches

Chicago Cubs
Chicago Cubs Latest matches
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 21, 2026 - MLB

Chicago Cubs
11 :  2
Detroit Tigers

Jul 20, 2026 - MLB

Chicago Cubs
6 :  8
Detroit Tigers

Jul 19, 2026 - MLB

Chicago Cubs
10 :  1
Minnesota Twins

Jul 18, 2026 - MLB

Chicago Cubs
6 :  2
Minnesota Twins

Jul 17, 2026 - MLB

Chicago Cubs
2 :  5
Minnesota Twins

Jul 12, 2026 - MLB

Cincinnati Reds
4 :  8
Chicago Cubs
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 21, 2026 - MLB

Chicago Cubs
11 :  2
Detroit Tigers

Jul 20, 2026 - MLB

Chicago Cubs
6 :  8
Detroit Tigers

Jul 19, 2026 - MLB

Chicago Cubs
10 :  1
Minnesota Twins

Jul 18, 2026 - MLB

Chicago Cubs
6 :  2
Minnesota Twins

Jul 17, 2026 - MLB

Chicago Cubs
2 :  5
Minnesota Twins

Jul 5, 2026 - MLB

Chicago Cubs
6 :  4
St. Louis Cardinals
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 12, 2026 - MLB

Cincinnati Reds
4 :  8
Chicago Cubs

Jul 11, 2026 - MLB

Cincinnati Reds
3 :  5
Chicago Cubs

Jul 10, 2026 - MLB

Cincinnati Reds
4 :  0
Chicago Cubs

Jul 9, 2026 - MLB

Baltimore Orioles
3 :  2
Chicago Cubs

Jul 8, 2026 - MLB

Baltimore Orioles
7 :  9
Chicago Cubs

Jul 7, 2026 - MLB

Baltimore Orioles
2 :  5
Chicago Cubs
Detroit Tigers
Detroit Tigers Latest matches
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 21, 2026 - MLB

Chicago Cubs
11 :  2
Detroit Tigers

Jul 20, 2026 - MLB

Chicago Cubs
6 :  8
Detroit Tigers

Jul 19, 2026 - MLB

Los Angeles Angels
3 :  2
Detroit Tigers

Jul 18, 2026 - MLB

Los Angeles Angels
0 :  7
Detroit Tigers

Jul 17, 2026 - MLB

Los Angeles Angels
1 :  2
Detroit Tigers

Jul 12, 2026 - MLB

Detroit Tigers
0 :  5
Philadelphia Phillies
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 12, 2026 - MLB

Detroit Tigers
0 :  5
Philadelphia Phillies

Jul 11, 2026 - MLB

Detroit Tigers
2 :  4
Philadelphia Phillies

Jul 10, 2026 - MLB

Detroit Tigers
10 :  2
Philadelphia Phillies

Jul 9, 2026 - MLB

Detroit Tigers
4 :  1
Athletics

Jul 8, 2026 - MLB

Detroit Tigers
6 :  1
Athletics

Jul 7, 2026 - MLB

Detroit Tigers
6 :  2
Athletics
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 21, 2026 - MLB

Chicago Cubs
11 :  2
Detroit Tigers

Jul 20, 2026 - MLB

Chicago Cubs
6 :  8
Detroit Tigers

Jul 19, 2026 - MLB

Los Angeles Angels
3 :  2
Detroit Tigers

Jul 18, 2026 - MLB

Los Angeles Angels
0 :  7
Detroit Tigers

Jul 17, 2026 - MLB

Los Angeles Angels
1 :  2
Detroit Tigers

Jul 5, 2026 - MLB

Texas Rangers
3 :  6
Detroit Tigers

Chicago Cubs against Detroit Tigers : Head to Head (H2H)

Chicago Cubs

50 %

Detroit Tigers

50 %

Jul 21, 2026 - MLB

Chicago Cubs
11 :  2
Detroit Tigers

Jul 20, 2026 - MLB

Chicago Cubs
6 :  8
Detroit Tigers

Jun 7, 2025 - MLB

Detroit Tigers
1 :  6
Chicago Cubs

Jun 6, 2025 - MLB

Detroit Tigers
3 :  1
Chicago Cubs

Aug 22, 2024 - MLB

Chicago Cubs
10 :  2
Detroit Tigers

Aug 21, 2024 - MLB

Chicago Cubs
2 :  8
Detroit Tigers
Chicago Cubs vs Detroit Tigers Picks

Chicago Cubs - Detroit Tigers Key Points

  1. Detroit leads the all-time series vs. the Cubs, 34-29-1.
  2. Detroit is 22-29 ATS (run line) on the road; Chicago is 20-31 ATS (run line) at home.
  3. The OVER is 24-25-2 for the Tigers on the road and 28-23 for the Cubs at home.
  4. Betting Public: 30% of moneyline tickets and 41% of the handle are on the Tigers.
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Our Chicago Cubs vs Detroit Tigers Prediction

My initial thought for this game was to go with the Tigers moneyline (+100) since Montero is hard to hit and could keep the Cubs lineup in check. But then I examined his game log closer and saw that he has a handful of 5+ inning starts under his belt, but has gone 1 2/3 to 3 1/3 innings in his last five starts. Now, he has held teams scoreless in four of them, so I think he’ll get the Tigers on track early. The Tigers bullpen has a 3.86 ERA, so they may be just fine if Montero gets pulled early. Detroit has not been great at the plate (.227 since the Break), but Rea has been sharp at home, which has me thinking now that the UNDER is the best bet.

Our Tigers vs. Cubs Pick: UNDER 8

Prediction:

 

UNDER 8

-115
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.