Philadelphia 76ers vs Detroit Pistons Prediction & Picks - NBA

USA - NBA

Philadelphia 76ers
4/4/26 19:00
Detroit Pistons

Prediction:

 

The Sixers will win

+140
$250 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Lou Aguila | in NBA Picks

6-1 in their last 7 games at home, the Philadelphia 76ers enter Saturday’s showdown with the Detroit Pistons as tantalizing +140 home underdogs.

Momentum: Despite missing Cade Cunningham due to a collapsed lung, the Detroit Pistons still own the best record in the East at 56-21 after winning six of their last eight games, including a 113-108 win over the Minnesota Timberwolves on April 2. The Philadelphia 76ers have also caught fire recently, winning four of their last five games and six of their last eight.

Matchup: The Pistons are eyeing a sweep of the Sixers in the regular season after winning each of their first three meetings this season. Detroit even blew out the Sixers 131-109 in their most recent meeting on March 12.

Players to Watch: Pistons big man Jalen Duren has ramped up his offense, averaging 24.7 points on 67 FG% in the last 9 games. Sixers guard Tyrese Maxey averages 24.5 points and 8.5 assists over the last four games since his return from a right pinkie injury.

Hot on the Board: The Sixers are +140 home underdogs and -110 to cover the spread at +130. The Pistons, listed as -165 road favorites, will need to win by four points to overcome the 3.5-point handicap. The over/under stands at 226.5 points.

Up to $250 to bet on Philadelphia 76ers - Detroit Pistons! 

Limited Offer. Currently at Caesars Sportsbook

Philadelphia 76ers vs Detroit Pistons Form

Table

Teams % P W L Series
3 Detroit Pistons
0.732 82 60 22 3
13 Philadelphia 76ers
0.549 82 45 37 2

Philadelphia 76ers and Detroit Pistons Latest Matches

Philadelphia 76ers
Philadelphia 76ers Latest matches
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 3, 2026 - NBA

Philadelphia 76ers
115 :  103
Minnesota Timberwolves

Apr 1, 2026 - NBA

Washington Wizards
131 :  153
Philadelphia 76ers

Mar 30, 2026 - NBA

Miami Heat
119 :  109
Philadelphia 76ers

Mar 28, 2026 - NBA

Charlotte Hornets
114 :  118
Philadelphia 76ers

Mar 25, 2026 - NBA

Philadelphia 76ers
157 :  137
Chicago Bulls

Mar 23, 2026 - NBA

Philadelphia 76ers
103 :  123
Oklahoma City Thunder
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 3, 2026 - NBA

Philadelphia 76ers
115 :  103
Minnesota Timberwolves

Mar 25, 2026 - NBA

Philadelphia 76ers
157 :  137
Chicago Bulls

Mar 23, 2026 - NBA

Philadelphia 76ers
103 :  123
Oklahoma City Thunder

Mar 15, 2026 - NBA

Philadelphia 76ers
109 :  103
Portland Trail Blazers

Mar 14, 2026 - NBA

Philadelphia 76ers
104 :  97
Brooklyn Nets

Mar 10, 2026 - NBA

Philadelphia 76ers
139 :  129
Memphis Grizzlies
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 1, 2026 - NBA

Washington Wizards
131 :  153
Philadelphia 76ers

Mar 30, 2026 - NBA

Miami Heat
119 :  109
Philadelphia 76ers

Mar 28, 2026 - NBA

Charlotte Hornets
114 :  118
Philadelphia 76ers

Mar 21, 2026 - NBA

Utah Jazz
116 :  126
Philadelphia 76ers

Mar 19, 2026 - NBA

Sacramento Kings
118 :  139
Philadelphia 76ers

Mar 17, 2026 - NBA

Denver Nuggets
124 :  96
Philadelphia 76ers
Detroit Pistons
Detroit Pistons Latest matches
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 2, 2026 - NBA

Detroit Pistons
113 :  108
Minnesota Timberwolves

Mar 31, 2026 - NBA

Detroit Pistons
127 :  116
Toronto Raptors

Mar 30, 2026 - NBA

Oklahoma City Thunder
114 :  110
Detroit Pistons

Mar 28, 2026 - NBA

Minnesota Timberwolves
87 :  109
Detroit Pistons

Mar 26, 2026 - NBA

Detroit Pistons
129 :  108
New Orleans Pelicans

Mar 25, 2026 - NBA

Detroit Pistons
129 :  130
Atlanta Hawks
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 2, 2026 - NBA

Detroit Pistons
113 :  108
Minnesota Timberwolves

Mar 31, 2026 - NBA

Detroit Pistons
127 :  116
Toronto Raptors

Mar 26, 2026 - NBA

Detroit Pistons
129 :  108
New Orleans Pelicans

Mar 25, 2026 - NBA

Detroit Pistons
129 :  130
Atlanta Hawks

Mar 23, 2026 - NBA

Detroit Pistons
113 :  110
Los Angeles Lakers

Mar 20, 2026 - NBA

Detroit Pistons
115 :  101
Golden State Warriors
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 30, 2026 - NBA

Oklahoma City Thunder
114 :  110
Detroit Pistons

Mar 28, 2026 - NBA

Minnesota Timberwolves
87 :  109
Detroit Pistons

Mar 19, 2026 - NBA

Washington Wizards
95 :  117
Detroit Pistons

Mar 17, 2026 - NBA

Washington Wizards
117 :  130
Detroit Pistons

Mar 15, 2026 - NBA

Toronto Raptors
119 :  108
Detroit Pistons

Mar 10, 2026 - NBA

Brooklyn Nets
100 :  138
Detroit Pistons

Philadelphia 76ers against Detroit Pistons : Head to Head (H2H)

Philadelphia 76ers

17 %

Detroit Pistons

83 %

Mar 12, 2026 - NBA

Detroit Pistons
131 :  109
Philadelphia 76ers

Nov 14, 2025 - NBA

Detroit Pistons
114 :  105
Philadelphia 76ers

Nov 9, 2025 - NBA

Philadelphia 76ers
108 :  111
Detroit Pistons

Feb 7, 2025 - NBA

Detroit Pistons
125 :  112
Philadelphia 76ers

Nov 30, 2024 - NBA

Detroit Pistons
96 :  111
Philadelphia 76ers

Oct 30, 2024 - NBA

Philadelphia 76ers
95 :  105
Detroit Pistons

Players list

Philadelphia 76ers
Philadelphia 76ers
A. Drummond K. Oubre Jr.

T. Maxey

V. Edgecombe

P. George

Detroit Pistons
Detroit Pistons
J. Duren A. Thompson

D. Jenkins

T. Harris

D. Robinson

Substitutes

Philadelphia 76ers
Philadelphia 76ers
A. Bona

J. Edwards

K. Lowry

C. Payne

Q. Grimes

J. Walker

M. Beauchamp

D. Barlow

T. Watford

Detroit Pistons
Detroit Pistons
J. Green K. Huerter T. Smith

C. Lanier

M. Sasser

C. LeVert

R. Holland

P. Reed

Philadelphia 76ers - Detroit Pistons Key Points

  1. Philadelphia is 6-1 SU in its last 7 games at home.
  2. Philadelphia is 4-1 SU in its last 5 games.
  3. Detroit is 14-6 SU in its last 20 games on the road.
  4. Detroit is 2-12 ATS in its last 14 games when playing on the road against Philadelphia.
Up to $250 to bet on Philadelphia 76ers - Detroit Pistons! 

Limited Offer. Currently at Caesars Sportsbook

Our Philadelphia 76ers vs Detroit Pistons Prediction

Fearless Forecast: The Sixers end their losing streak against the Pistons 115-113

Best Pick: Sixers win (+140). Philadelphia will protect its home court and avoid a sweep at the hands of the Pistons. The Sixers are gaining momentum in the homestretch mark of the season, winning six of their last eight games.

After going through a barrage of challenges this season, Philadelphia has steadily rounded into form with the return of Tyrese Maxey from injury and Paul George from suspension.

The availability of Joel Embiid (game-time decision - knee) will significantly increase the Sixers’ winning probability for this game because his presence alone will create a lot of mismatched problems for the Pistons, who will be missing Cunningham and enforcer Isaiah Stewart (calf) in this game. Philadelphia is 6-1 SU in its last 7 games at home.

Our betting predictions for the Detroit Pistons vs. the Philadelphia 76ers: The Sixers will win

Prediction:

 

The Sixers will win

+140
$250 offered for betting!

Right now, claim $250 for your Philadelphia 76ers vs Detroit Pistons wager!

Caesars Welcome BonusCaesars Sportsbook is offering an extraordinary opportunity for new bettors to unlock a total of $250 thanks to our code: STRADERDYW! You can access this promo for the Philadelphia 76ers vs Detroit Pistons matchup!

New users can access the bonus on Caesars Sportsbook Mobile or through the website by creating an account during the promotion period and registering using a special promo code. This offer is a chance for newcomers to experience the thrill of sports betting with a significant boost, courtesy of Caesars Sportsbook.

$250 available for Philadelphia 76ers vs Detroit Pistons

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Philadelphia 76ers vs Detroit Pistons Picks