Cincinnati Bengals vs Detroit Lions Prediction & Picks - NFL

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Cincinnati Bengals
10/5/25 16:25
Detroit Lions

Prediction:

 

Detroit Lions -9.5 Alternate Spread

-127
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 by Matt Lowrimore | in NFL Picks

One of the late games on the Week 5 NFL Sunday slate will see the Cincinnati Bengals take on the Detroit Lions. Let’s take a look at the match statistics and predictions for this game between the Bengals and the Lions.

Detroit enters this game with a record of 3-1, having most recently beaten the Cleveland Browns in Week 4 by a score of 34-10. The Lions’ offense had a total of 277 yards, while its defense allowed 249 yards. Quarterback Jared Goff threw for 168 yards, two touchdowns, and one interception, while running back Jahmyr Gibbs led the team in rushing with 91 yards and one touchdown.

As for Cincinnati, they enter this game with a record of 2-2, having most recently lost to the Denver Broncos in Week 4 by a score of 28-3. The Bengals’ offense had a total of 129 yards, while its defense allowed 512 yards. Quarterback Jake Browning threw for 125 yards, while running back Chase Brown led the team in rushing with 40 yards.

Cincinnati Bengals vs Detroit Lions Form

Table

Teams Pts P W L
15 Detroit Lions
0.529 17 9 8
23 Cincinnati Bengals
0.353 17 6 11

Cincinnati Bengals and Detroit Lions Latest Matches

Cincinnati Bengals
Cincinnati Bengals Latest matches
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 29, 2025 - NFL

Denver Broncos
28 :  3
Cincinnati Bengals

Sep 21, 2025 - NFL

Minnesota Vikings
48 :  10
Cincinnati Bengals

Sep 14, 2025 - NFL

Cincinnati Bengals
31 :  27
Jacksonville Jaguars

Sep 7, 2025 - NFL

Cleveland Browns
16 :  17
Cincinnati Bengals

Jan 4, 2025 - NFL

Pittsburgh Steelers
17 :  19
Cincinnati Bengals

Dec 28, 2024 - NFL

Cincinnati Bengals
30 :  24
Denver Broncos
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 14, 2025 - NFL

Cincinnati Bengals
31 :  27
Jacksonville Jaguars

Dec 28, 2024 - NFL

Cincinnati Bengals
30 :  24
Denver Broncos

Dec 22, 2024 - NFL

Cincinnati Bengals
24 :  6
Cleveland Browns

Dec 1, 2024 - NFL

Cincinnati Bengals
38 :  44
Pittsburgh Steelers

Oct 27, 2024 - NFL

Cincinnati Bengals
17 :  37
Philadelphia Eagles

Oct 6, 2024 - NFL

Cincinnati Bengals
38 :  41
Baltimore Ravens
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 29, 2025 - NFL

Denver Broncos
28 :  3
Cincinnati Bengals

Sep 21, 2025 - NFL

Minnesota Vikings
48 :  10
Cincinnati Bengals

Sep 7, 2025 - NFL

Cleveland Browns
16 :  17
Cincinnati Bengals

Jan 4, 2025 - NFL

Pittsburgh Steelers
17 :  19
Cincinnati Bengals

Dec 15, 2024 - NFL

Tennessee Titans
27 :  37
Cincinnati Bengals

Dec 9, 2024 - NFL

Dallas Cowboys
20 :  27
Cincinnati Bengals
Detroit Lions
Detroit Lions Latest matches
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 28, 2025 - NFL

Detroit Lions
34 :  10
Cleveland Browns

Sep 22, 2025 - NFL

Baltimore Ravens
30 :  38
Detroit Lions

Sep 14, 2025 - NFL

Detroit Lions
52 :  21
Chicago Bears

Sep 7, 2025 - NFL

Green Bay Packers
27 :  13
Detroit Lions

Jan 18, 2025 - NFL

Detroit Lions
31 :  45
Washington Commanders

Jan 5, 2025 - NFL

Detroit Lions
31 :  9
Minnesota Vikings
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 28, 2025 - NFL

Detroit Lions
34 :  10
Cleveland Browns

Sep 14, 2025 - NFL

Detroit Lions
52 :  21
Chicago Bears

Jan 18, 2025 - NFL

Detroit Lions
31 :  45
Washington Commanders

Jan 5, 2025 - NFL

Detroit Lions
31 :  9
Minnesota Vikings

Dec 15, 2024 - NFL

Detroit Lions
42 :  48
Buffalo Bills

Dec 5, 2024 - NFL

Detroit Lions
34 :  31
Green Bay Packers
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 22, 2025 - NFL

Baltimore Ravens
30 :  38
Detroit Lions

Sep 7, 2025 - NFL

Green Bay Packers
27 :  13
Detroit Lions

Dec 30, 2024 - NFL

San Francisco 49ers
34 :  40
Detroit Lions

Dec 22, 2024 - NFL

Chicago Bears
17 :  34
Detroit Lions

Nov 24, 2024 - NFL

Indianapolis Colts
6 :  24
Detroit Lions

Nov 10, 2024 - NFL

Houston Texans
23 :  26
Detroit Lions

Cincinnati Bengals - Detroit Lions Key Points

  1. The Bengals are 1-3 ATS this season
  2. The Lions are 3-1 ATS this season
  3. The Bengals are averaging 15.3 points per game this season
  4. The Lions are averaging 34.3 points per game this season

Our Cincinnati Bengals vs Detroit Lions Prediction

Since the Bengals lost quarterback Joe Burrow to injury, they have simply been awful. In the last two games that Jake Browning has started, Cincinnati is averaging 6.5 points per game. 

As for Detroit, they have looked like one of the best teams in the league following their loss in Week 1. Since the loss to the Green Bay Packers in Week 1, the Lions’ offense has averaged 41.3 points per game.

The Lions have a potent rushing attack, and their passing offense can also be explosive at any time. Therefore, given the lack of ability the Bengals have shown over the last two weeks, our Cincinnati Bengals vs Detroit Lions prediction is: Detroit Lions -9.5 Alternate Spread.

Prediction:

 

Detroit Lions -9.5 Alternate Spread

-127
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Cincinnati Bengals vs Detroit Lions Picks