Cleveland Guardians vs Colorado Rockies Prediction & Picks - MLB

Prediction published on 7/28/25, 2:58 PM  by Carlos Zabala | Modified on 8/4/25 at 10:25 PM in MLB Picks

At odds as low as -235, the Guardians will be favorites to win the first game of the series against the weak Rockies. However, the Guardians, even in winning seasons in recent years, struggled to beat Colorado, so much so that both teams won five each in their last 10 games.

Ryan McMahon left for the Rockies in a trade to the Yankees, in a deal that infuriated die-hard Rockies fans, arguing that they received nothing valuable for the now-ex-Colorado Rockie. In Sunday's loss to the Orioles, Venezuelan Orlando Arcia came in to cover third base and went 1-for-4 batting ninth.

On Sunday, the Guards lost a key game to the Royals, but on Saturday they won the second game of the doubleheader 6-4 with another home run from Kwan and Clase's 24th save. However, before losing that series in Kansas City, the Guardians had won the previous four.