Baltimore Orioles vs Colorado Rockies Prediction & Picks - MLB

Prediction published on 7/25/25, 3:22 PM  by Carlos Zabala | Modified on 7/25/25 at 9:40 PM in MLB Picks

After losing three of four games in Cleveland against the Guardians, the Orioles took Game 4 on Thursday, winning it four games in a row, and now return to Camden Yards for a stay in the Channel. The Orioles-Rockies series is, therefore, a series between last-place teams in their division, but the Orioles will start as favorites at odds of around -225 to win it.

While the Rockies rested on Thursday, the Orioles won 4-3 at Progressive Field. The game was tied 3-3 until the seventh inning, when Henderson got a key RBI single off Alex Jackson. Relievers Dominguez and Soto combined to get the final six outs of the game, striking out four.

But also, the Rockies are coming off a win in their most recent series against the Cardinals at Coors Field; on Wednesday, they won 6-0, blanking the Cards in what was their first shutout in 220 games. In that game, Toar hit his fifth home run and Beck his 19th double.