Tampa Bay Rays vs Cleveland Guardians Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Travis Pulver in MLB Picks
The Tampa Bay Rays (61-43, 37-15 Home) will go for the series sweep today when they host the Cleveland Guardians in the third game of a three-game weekend series at Tropicana Field in St. Petersburg, FL. First Pitch is scheduled for 12:15 p.m. EST with coverage provided by Peacock.
In Friday’s game, the offense led the way for the Rays, as they clobbered the Guardians 11-3. But in Saturday’s game, the lineup did enough by scoring three runs, but it was the pitching staff throwing a shutout that led the way.
Drew Rasmussen is scheduled to get the start for the Rays. He is 8-5 in 19 starts with a 0.98 WHIP. Rasmussen has gone 5-3 at home in nine starts with a 3.51 ERA and a .220 OBA. He only lasted 2 1/3 innings in his last home start, getting chased by the Yankees after just 2 1/3 innings (seven hits, six earned runs).
As for Cleveland, the Guardians are scheduled to start Parker Messick. Messick has gone 8-5 in 20 starts with a 2.68 ERA and a 1.05 WHIP. He has often had some of his best stuff on the road, where he is 5-3 in nine starts with a 2.35 ERA and a .194 OBA.
Limited Offer. Currently at DraftKings
Tampa Bay Rays vs Cleveland Guardians Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
3
|
0.587 | 104 | 61 | 43 |
|
13
|
0.509 | 106 | 54 | 52 |
Tampa Bay Rays and Cleveland Guardians Latest Matches
5/6 (83%)
1/6 (17%)
Jul 25, 2026 - MLB
Jul 24, 2026 - MLB
Jul 23, 2026 - MLB
Jul 22, 2026 - MLB
Jul 21, 2026 - MLB
Jul 20, 2026 - MLB
4/6 (67%)
2/6 (33%)
Jul 25, 2026 - MLB
Jul 24, 2026 - MLB
Jul 12, 2026 - MLB
Jul 11, 2026 - MLB
Jul 10, 2026 - MLB
Jul 9, 2026 - MLB
3/6 (50%)
3/6 (50%)
Jul 23, 2026 - MLB
Jul 22, 2026 - MLB
Jul 21, 2026 - MLB
Jul 20, 2026 - MLB
Jul 19, 2026 - MLB
Jul 18, 2026 - MLB
2/6 (33%)
4/6 (67%)
Jul 25, 2026 - MLB
Jul 24, 2026 - MLB
Jul 23, 2026 - MLB
Jul 22, 2026 - MLB
Jul 21, 2026 - MLB
Jul 20, 2026 - MLB
3/6 (50%)
3/6 (50%)
Jul 23, 2026 - MLB
Jul 22, 2026 - MLB
Jul 21, 2026 - MLB
Jul 20, 2026 - MLB
Jul 19, 2026 - MLB
Jul 18, 2026 - MLB
4/6 (67%)
2/6 (33%)
Jul 25, 2026 - MLB
Jul 24, 2026 - MLB
Jul 12, 2026 - MLB
Jul 11, 2026 - MLB
Jul 10, 2026 - MLB
Jul 9, 2026 - MLB
Tampa Bay Rays against Cleveland Guardians : Head to Head (H2H)
67 %
33 %
Jul 25, 2026 - MLB
Jul 24, 2026 - MLB
Apr 29, 2026 - MLB
Apr 28, 2026 - MLB
Apr 27, 2026 - MLB
Sep 7, 2025 - MLB
Tampa Bay Rays - Cleveland Guardians Key Points
- Cleveland leads the all-time series vs. the Rays, 115-89.
- Cleveland is 28-25 ATS (run line) on the road; Tampa Bay is 36-16 ATS (run line) at home
- The OVER is 23-30 for the Guardians on the road and 23-25-4 for the Rays at home.
- Betting Public: 65% of runline tickets and 68% of the handle are on the Rays.
Limited Offer. Currently at DraftKings
Our Tampa Bay Rays vs Cleveland Guardians Prediction
This is a tough one to call. Both lineups are hitting pretty well at the moment: the Guardians, .258, and the Rays, .303. So, it will probably go over, right? Maybe, but against these two starting pitchers, I’d expect a quiet day at the plate for both teams. Then again, the total is only seven runs, so it's not like it will take a lot to go over. Since the total could go either way, I’m picking a winner. But I don’t see enough value in the Rays ML, so how about the run line? Tampa Bay has the firepower to win this one by two. At these odds, it is a solid value play.
Our Cleveland vs. Tampa Bay Pick: Rays -1.5
A Welcome Bonus for Tampa Bay Rays vs Cleveland Guardians!

Looking to place a bet on Tampa Bay Rays vs Cleveland Guardians? For this MLB match, DraftKings will treat you to an exclusive offer: $150 in bonus bets, no promo code needed! Take advantage while you still can!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.