Seattle Mariners vs Cleveland Guardians Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Matt Lowrimore | in MLB Picks
The first Sunday night game of the 2026 MLB season will be an American League matchup between the Seattle Mariners and the Cleveland Guardians. Let's take a look at the match statistics and predictions for this game between the Mariners and the Guardians.
To conclude this series on Sunday, Cleveland is set to start Slade Cecconi, who is coming off a 2025 season where he went 7-7 and had an ERA of 4.30. While these numbers were below average, Cecconi was decent on the road last season, posting an ERA of 3.75. That being said, he didn't face the Mariners in 2025 and could be in for a rough outing against a solid-looking Mariners' offense.
As for Seattle, they are scheduled to start Emerson Hancock on Sunday. Hancock finished the 2025 season with a record of 4-5 and had an ERA of 4.90. While these numbers are not good, Hancock did have success against Cleveland, pitching 7.0 innings and allowing no earned runs against them.
Limited Offer. Currently at DraftKings
Seattle Mariners vs Cleveland Guardians Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
19
|
0.487 | 119 | 58 | 61 |
|
24
|
0.471 | 119 | 56 | 63 |
Seattle Mariners and Cleveland Guardians Latest Matches
3/6 (50%)
3/6 (50%)
Mar 27, 2026 - MLB
Mar 26, 2026 - MLB
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 27, 2026 - MLB
Mar 26, 2026 - MLB
Mar 21, 2026 - MLB Spring Training
Mar 18, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 15, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 14, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 27, 2026 - MLB
Mar 26, 2026 - MLB
Mar 24, 2026 - MLB Spring Training
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 22, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 16, 2026 - MLB Spring Training
Mar 15, 2026 - MLB Spring Training
Mar 12, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 27, 2026 - MLB
Mar 26, 2026 - MLB
Mar 24, 2026 - MLB Spring Training
Mar 23, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Seattle Mariners against Cleveland Guardians : Head to Head (H2H)
67 %
33 %
Mar 27, 2026 - MLB
Mar 26, 2026 - MLB
Mar 20, 2026 - MLB Spring Training
Feb 26, 2026 - MLB Spring Training
Aug 31, 2025 - MLB
Aug 30, 2025 - MLB
Seattle Mariners - Cleveland Guardians Key Points
- Slade Cecconi had an ERA of 4.30 in 2025
- Emerson Hancock had an ERA of 4.90 in 2025
- Slade Cecconi did not face Seattle in 2025
- Emerson Hancock had an ERA of 0.00 vs Cleveland in 2025
Limited Offer. Currently at DraftKings
Our Seattle Mariners vs Cleveland Guardians Prediction
Seattle is the betting favorite for Sunday's series finale; however, they still look to be the best betting option. The Mariners appear to have the advantage in starting pitching with Hancock making his first appearance of 2026. While he was not great in 2025, Hancock has had success against the Guardians, which could translate to a solid outing in this matchup.
As for Cleveland's starter, Slade Cecconi, he was also not great in 2025, but did not face the Mariners last season, who look to have a solid lineup in 2026. Therefore, because Hancock has had previous success against Cleveland and the Seattle lineup is unknown to Cecconi, our Seattle Mariners vs Cleveland Guardians prediction is: Seattle Mariners ML.All tips are fully researched and given in good faith, but profits cannot be guaranteed.
