Seattle Mariners vs Cleveland Guardians Prediction & Picks - MLB
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by Lou Aguila | in MLB Picks
The Seattle Mariners, priced at +113 to cover -1.5 runs, will try to secure their second SU and ATS win of the season when they resume their series with the Cleveland Guardians.
Momentum: The Seattle Mariners bounced back from an opening day loss to the Cleveland Guardians, 4-6, with a 5-1 win in Game 2. The series is tied heading into Saturday’s Game 3 of this four-game series.
The Matchup: Cleveland is now 1-4 against the Mariners following Friday’s loss. Guardians lefty Joey Cantilo (3.21 ERA in 2025) will start on Saturday against Mariners’ right-handed pitcher Bryan Woo (15-7, 2.90 ERA in 2025).
Hot on the Board: The Mariners opened at -194 for Game 3, while the underdog Guardians got a +159 on DraftKings. Seattle catches a +113 price on the -1.5 run line.
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Seattle Mariners vs Cleveland Guardians Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
12
|
0.518 | 83 | 43 | 40 |
|
13
|
0.5 | 84 | 42 | 42 |
Seattle Mariners and Cleveland Guardians Latest Matches
3/6 (50%)
3/6 (50%)
Mar 27, 2026 - MLB
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Mar 23, 2026 - MLB Spring Training
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Mar 20, 2026 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 27, 2026 - MLB
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Mar 18, 2026 - MLB Spring Training
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4/6 (67%)
2/6 (33%)
Mar 23, 2026 - MLB Spring Training
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Mar 17, 2026 - MLB Spring Training
Mar 14, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 27, 2026 - MLB
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Mar 23, 2026 - MLB Spring Training
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Mar 21, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 22, 2026 - MLB Spring Training
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Mar 16, 2026 - MLB Spring Training
Mar 15, 2026 - MLB Spring Training
Mar 12, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 27, 2026 - MLB
Mar 26, 2026 - MLB
Mar 24, 2026 - MLB Spring Training
Mar 23, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Seattle Mariners against Cleveland Guardians : Head to Head (H2H)
67 %
33 %
Mar 27, 2026 - MLB
Mar 26, 2026 - MLB
Mar 20, 2026 - MLB Spring Training
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Aug 31, 2025 - MLB
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Seattle Mariners - Cleveland Guardians Key Points
- The total has gone UNDER in 4 of Seattle's last 6 games against Cleveland.
- Seattle is 4-1 SU in its last 5 games when playing at home against Cleveland.
- The total has gone UNDER in 6 of Cleveland's last 6 games played on a Saturday.
- Seattle is 13-6 SU in its last 19 games against an opponent in the American League Central Division
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Our Seattle Mariners vs Cleveland Guardians Prediction
Fearless Forecast: the Mariners take Game 3 with a 4-2 win over the Guardians
Best Bet: The Mariners -1.5 runs. Bryan Woo will try to pick up where he left off last season, when he compiled an impressive 15-7 record with a 2.90 ERA. The Mariners’ bullpen also made its presence felt in Game 2, containing the Guardians’ batters down the stretch. If Woo gives the Mariners a good five-inning stint and the relief pitchers do their thing again, the Mariners would be in a terrific position to win and cover because this team can score at any point of the match, given their loaded batters’ row led by MVP contender Cal Raleigh.
Secondary Pick: Under 7 runs. We’ve got two terrific starters going head-to-head on Saturday as Bryan Woo will test Joey Cantillo. Woo posted a 2.93 ERA and averaged 7.6 strikeouts over his final five starts in 2025. Cantillo also impressed with a 1.55 ERA over his last five stints in 2025.
Our betting prediction for the Cleveland Guardians vs. the Seattle Mariners: The Mariners -1.5 Runs
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
