Seattle Mariners vs Cleveland Guardians Prediction & Picks - MLB
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by Stephen Abiola | in MLB Picks
Seattle Mariners versus Cleveland Guardians is an American League contest on Thursday night at T-Mobile Park. The Mariners will be looking to start the new season with a win in this four-game series as they prepare to defend their AL West title. They come into the new season with arguably the most talented squad in the division, including Cal Raleigh, a Platinum Glove-winning catcher. Seattle should dominate the AL West if Raleigh continues to hit those home runs.
Cleveland Guardians, on the other side of the grass, will enter the new season hoping that their group of young players has matured. Their most noticeable move to bolster the squad was to sign a hitter, Rhys Hoskins, to a minor league deal. However, Jose Ramirez, who has carried them through the storm for years, will once again be tasked with leading the 2026 campaign. Chase DeLauter can also reach his All-Star potential if he stays healthy.
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Seattle Mariners vs Cleveland Guardians Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
12
|
0.518 | 83 | 43 | 40 |
|
13
|
0.5 | 84 | 42 | 42 |
Seattle Mariners and Cleveland Guardians Latest Matches
4/6 (67%)
2/6 (33%)
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 18, 2026 - MLB Spring Training
2/6 (33%)
4/6 (67%)
Mar 21, 2026 - MLB Spring Training
Mar 18, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 15, 2026 - MLB Spring Training
Mar 13, 2026 - MLB Spring Training
Mar 11, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 14, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 24, 2026 - MLB Spring Training
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 22, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 16, 2026 - MLB Spring Training
Mar 15, 2026 - MLB Spring Training
Mar 12, 2026 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 24, 2026 - MLB Spring Training
Mar 23, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 14, 2026 - MLB Spring Training
Mar 13, 2026 - MLB Spring Training
Seattle Mariners against Cleveland Guardians : Head to Head (H2H)
67 %
33 %
Mar 20, 2026 - MLB Spring Training
Feb 26, 2026 - MLB Spring Training
Aug 31, 2025 - MLB
Aug 30, 2025 - MLB
Aug 29, 2025 - MLB
Jun 15, 2025 - MLB
Seattle Mariners - Cleveland Guardians Key Points
- The Mariners won four of their last six matches
- The Mariners won six of their last eight games against the Guardians.
- The Mariners won against the run line in three of their last five games.
- The Guardians lost against the run line in two of their last four matches.
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Our Seattle Mariners vs Cleveland Guardians Prediction
The Mariners are the -186 betting favorites. They weren’t that convincing during Spring Training, losing two of their last three games while giving up 19 runs. While at it, they won 20-8 against the Guardians, who surrendered five home runs. It was a kind of defeat that Stephen Vogt and his team will want to forget with a win on Thursday. However, they haven’t enjoyed much success against the Mariners lately, losing all three of their last meetings. In addition, the Mariners won their last five home games against the Guardians. We see them extending this record with a convincing opening-day victory.
Our prediction for Seattle Mariners vs Cleveland Guardians: Seattle Mariners to cover the -1.5 runline.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.