Seattle Mariners vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Seattle Mariners
3/26/26 22:10
Cleveland Guardians

Prediction:

 

Seattle Mariners to cover the -1.5 runline.

+125
$350 offered for betting!

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 by Stephen Abiola | in MLB Picks

Seattle Mariners versus Cleveland Guardians is an American League contest on Thursday night at T-Mobile Park. The Mariners will be looking to start the new season with a win in this four-game series as they prepare to defend their AL West title. They come into the new season with arguably the most talented squad in the division, including Cal Raleigh, a Platinum Glove-winning catcher. Seattle should dominate the AL West if Raleigh continues to hit those home runs.

Cleveland Guardians, on the other side of the grass, will enter the new season hoping that their group of young players has matured. Their most noticeable move to bolster the squad was to sign a hitter, Rhys Hoskins, to a minor league deal. However, Jose Ramirez, who has carried them through the storm for years, will once again be tasked with leading the 2026 campaign. Chase DeLauter can also reach his All-Star potential if he stays healthy.

Seattle Mariners vs Cleveland Guardians Form

Table

Teams Pts P W L
12 Cleveland Guardians
0.518 83 43 40
13 Seattle Mariners
0.5 84 42 42

Seattle Mariners and Cleveland Guardians Latest Matches

Seattle Mariners
Seattle Mariners Latest matches
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 23, 2026 - MLB Spring Training

San Diego Padres
10 :  3
Seattle Mariners

Mar 22, 2026 - MLB Spring Training

Chicago White Sox
2 :  4
Seattle Mariners

Mar 21, 2026 - MLB Spring Training

Seattle Mariners
1 :  7
Chicago Cubs

Mar 20, 2026 - MLB Spring Training

Cleveland Guardians
8 :  20
Seattle Mariners

Mar 19, 2026 - MLB Spring Training

Athletics
4 :  6
Seattle Mariners

Mar 18, 2026 - MLB Spring Training

Seattle Mariners
7 :  3
Milwaukee Brewers
L L W L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Mar 21, 2026 - MLB Spring Training

Seattle Mariners
1 :  7
Chicago Cubs

Mar 18, 2026 - MLB Spring Training

Seattle Mariners
7 :  3
Milwaukee Brewers

Mar 17, 2026 - MLB Spring Training

Seattle Mariners
6 :  9
San Diego Padres

Mar 15, 2026 - MLB Spring Training

Seattle Mariners
6 :  3
Cincinnati Reds

Mar 13, 2026 - MLB Spring Training

Seattle Mariners
7 :  10
Los Angeles Dodgers

Mar 11, 2026 - MLB Spring Training

Seattle Mariners
7 :  11
Colorado Rockies
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 23, 2026 - MLB Spring Training

San Diego Padres
10 :  3
Seattle Mariners

Mar 22, 2026 - MLB Spring Training

Chicago White Sox
2 :  4
Seattle Mariners

Mar 20, 2026 - MLB Spring Training

Cleveland Guardians
8 :  20
Seattle Mariners

Mar 19, 2026 - MLB Spring Training

Athletics
4 :  6
Seattle Mariners

Mar 17, 2026 - MLB Spring Training

Colorado Rockies
6 :  10
Seattle Mariners

Mar 14, 2026 - MLB Spring Training

Los Angeles Angels
6 :  2
Seattle Mariners
Cleveland Guardians
Cleveland Guardians Latest matches
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 24, 2026 - MLB Spring Training

Arizona Diamondbacks
5 :  10
Cleveland Guardians

Mar 23, 2026 - MLB Spring Training

Arizona Diamondbacks
0 :  7
Cleveland Guardians

Mar 22, 2026 - MLB Spring Training

Cleveland Guardians
8 :  2
Cincinnati Reds

Mar 21, 2026 - MLB Spring Training

San Francisco Giants
10 :  7
Cleveland Guardians

Mar 20, 2026 - MLB Spring Training

Cleveland Guardians
8 :  20
Seattle Mariners

Mar 19, 2026 - MLB Spring Training

Cleveland Guardians
6 :  5
Kansas City Royals
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 22, 2026 - MLB Spring Training

Cleveland Guardians
8 :  2
Cincinnati Reds

Mar 20, 2026 - MLB Spring Training

Cleveland Guardians
8 :  20
Seattle Mariners

Mar 19, 2026 - MLB Spring Training

Cleveland Guardians
6 :  5
Kansas City Royals

Mar 16, 2026 - MLB Spring Training

Cleveland Guardians
2 :  5
Chicago Cubs

Mar 15, 2026 - MLB Spring Training

Cleveland Guardians
12 :  6
Athletics

Mar 12, 2026 - MLB Spring Training

Cleveland Guardians
1 :  0
Milwaukee Brewers
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Mar 24, 2026 - MLB Spring Training

Arizona Diamondbacks
5 :  10
Cleveland Guardians

Mar 23, 2026 - MLB Spring Training

Arizona Diamondbacks
0 :  7
Cleveland Guardians

Mar 21, 2026 - MLB Spring Training

San Francisco Giants
10 :  7
Cleveland Guardians

Mar 17, 2026 - MLB Spring Training

Cincinnati Reds
6 :  8
Cleveland Guardians

Mar 14, 2026 - MLB Spring Training

San Diego Padres
8 :  5
Cleveland Guardians

Mar 13, 2026 - MLB Spring Training

Los Angeles Angels
5 :  2
Cleveland Guardians

Seattle Mariners against Cleveland Guardians : Head to Head (H2H)

Seattle Mariners

67 %

Cleveland Guardians

33 %

Mar 20, 2026 - MLB Spring Training

Cleveland Guardians
8 :  20
Seattle Mariners

Feb 26, 2026 - MLB Spring Training

Seattle Mariners
8 :  7
Cleveland Guardians

Aug 31, 2025 - MLB

Cleveland Guardians
2 :  4
Seattle Mariners

Aug 30, 2025 - MLB

Cleveland Guardians
4 :  3
Seattle Mariners

Aug 29, 2025 - MLB

Cleveland Guardians
5 :  4
Seattle Mariners

Jun 15, 2025 - MLB

Seattle Mariners
6 :  0
Cleveland Guardians

Seattle Mariners - Cleveland Guardians Key Points

  1. The Mariners won four of their last six matches
  2. The Mariners won six of their last eight games against the Guardians.
  3. The Mariners won against the run line in three of their last five games.
  4. The Guardians lost against the run line in two of their last four matches.

Our Seattle Mariners vs Cleveland Guardians Prediction

The Mariners are the -186 betting favorites. They weren’t that convincing during Spring Training, losing two of their last three games while giving up 19 runs. While at it, they won 20-8 against the Guardians, who surrendered five home runs. It was a kind of defeat that Stephen Vogt and his team will want to forget with a win on Thursday. However, they haven’t enjoyed much success against the Mariners lately, losing all three of their last meetings. In addition, the Mariners won their last five home games against the Guardians. We see them extending this record with a convincing opening-day victory.

Our prediction for Seattle Mariners vs Cleveland Guardians: Seattle Mariners to cover the -1.5 runline.

Prediction:

 

Seattle Mariners to cover the -1.5 runline.

+125
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Seattle Mariners vs Cleveland Guardians Picks