San Francisco Giants vs Cleveland Guardians Prediction & Picks - MLB

Prediction published on 6/18/25, 6:15 PM  by Carlos Zabala | Modified on 2/11/26 at 8:27 AM in MLB Picks

The Guardians ended their losing streak and, after being swept by the Mariners, were able to score a Game 1 victory over the Giants 3-2 in the San Francisco Bay Area. The bullpen performed commendably. Festa, Smith, Gaddis, and Clase combined to get the final 12 outs and claim a victory as betting underdogs, as the Giants had closed as -155 favorites before the first pitch on Tuesday. However, they lost.

The previous game at Oracle Park also saw the warm welcome from Giants fans to Rafael Devers. In the acquisition that shook the entire MLB, the Dominican traveled to the other coast of the United States to meet his new teammates and introduce himself to the press. Within hours, he was batting third for the Giants. He went 2-for-5, struck out twice, but his hit was a double that drove in one of the Giants' two runs.

Veteran Verlander will return to pitching Wednesday for the Giants. He will come off the 15-day IL, is expected to throw around 80 pitches, and will be looking for his first W of the season. Logan Allen, the Guardians' choice to pitch Wednesday, has a 4.28 ERA.