Philadelphia Phillies vs Cleveland Guardians Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Bill Christy | in MLB Picks
The weekend series between the Cleveland Guardians (30-22) and the Philadelphia Phillies (25-25) will begin tonight in Philadelphia.
Cleveland is coming into the series on the back of a 6-game winning streak. After winning 2 of the last 3 in their series with the Reds, the Guardians completed a 4-game road sweep of the Detroit Tigers. It was pitching that made their last 3 games winnable. While they only scored a total of 10 runs, they were able to hold opponents to just 6 total runs.
Philly has been strong ever since they made their managerial change. Don Mattingly has seemed to be the change this team needed in leadership. They have fought their way back to .500 on the season, but are facing a possible 3-game losing streak here. They lost their last 2 games to the Reds, but will have their top arm on the mound here tonight.
The Phillies will start Cristopher Sanchez, who is 5-2 with a 1.82 ERA. Gavin Williams will go for the Guardians, who have also been stout this season. He is 6-3 with a 3.67 ERA. With both teams hitting under .235 and ranking outside the top 25 in MLB, runs may be tough to come by in this series-opening game.
Limited Offer. Currently at FanDuel
Our editorial team's top-confidence pick, every day.
Members only · free sign-up
Philadelphia Phillies vs Cleveland Guardians Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
8
|
0.543 | 162 | 88 | 74 |
|
11
|
0.525 | 162 | 85 | 77 |
Philadelphia Phillies and Cleveland Guardians Latest Matches
4/6 (67%)
2/6 (33%)
May 20, 2026 - MLB
May 19, 2026 - MLB
May 18, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
3/6 (50%)
3/6 (50%)
May 20, 2026 - MLB
May 19, 2026 - MLB
May 18, 2026 - MLB
May 10, 2026 - MLB
May 9, 2026 - MLB
May 8, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 14, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
6/6 (100%)
0/6 (0%)
May 21, 2026 - MLB
May 20, 2026 - MLB
May 19, 2026 - MLB
May 18, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
May 11, 2026 - MLB
6/6 (100%)
0/6 (0%)
May 21, 2026 - MLB
May 20, 2026 - MLB
May 19, 2026 - MLB
May 18, 2026 - MLB
May 7, 2026 - MLB
May 6, 2026 - MLB
Philadelphia Phillies against Cleveland Guardians : Head to Head (H2H)
100 %
0 %
May 10, 2025 - MLB
Jul 27, 2024 - MLB
Philadelphia Phillies - Cleveland Guardians Key Points
- The total has gone UNDER in 5 of Cleveland’s last 6 games against Philadelphia.
- The total has gone UNDER in 5 of Cleveland’s last 5 games when playing on the road against Philadelphia.
- The total has gone UNDER in 8 of Philadelphia’s last 10 games.
- The total has gone UNDER in 5 of Philadelphia’s last 6 games when playing as the favorite.
Limited Offer. Currently at FanDuel
Our Philadelphia Phillies vs Cleveland Guardians Prediction
This should be the strongest pitching matchup of the series. Sanchez is coming off a complete game shutout against the Pirates in his last start. He struck out 13 and only allowed 6 hits in the win. Gavin Williams went 6 strong against the Reds in his last start. He allowed just 2 runs and struck out 7 in the win. We like both to pitch well again here and hold the scoring to a minimum. If they can go deep in the game, there is no chance these teams will post more than 7 runs.
Our prediction for Philadelphia Phillies vs Cleveland Guardians: Under 7
All tips are fully researched and given in good faith, but profits cannot be guaranteed.