Minnesota Twins vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Minnesota Twins
9/11/26 20:10
Cleveland Guardians

Prediction:

 

Under 7.5 points

−105
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 by Carlos Zabala | in MLB Picks

The Guardians have a bye on Thursday, but on Wednesday they lost the rubber match of their series against the Orioles. Now the Guards face a couple of crucial series: first against the Twins and then the White Sox, with Stephen Vogt's team holding only a one-game lead over the Blue Jays for the final wild card spot.

The Guards fell 9-5 at Camden Yards in the series finale, a loss in which, however, De Lauter hit his 14th home run of the season and Lowe his 17th. Cleveland is confident that Parker Messick, starting Friday's game, can get them back on the winning track, especially since he's coming off a career-high in strikeouts, having fanned 12 Tigers in his previous start.

The Twins are coming off a 7-2 loss to the Tigers in Detroit. This diminishes their playoff chances; however, a sweep at home against the Guardians could give them a much-needed boost. Clemens and Bell continue to have outstanding seasons; each hit a solo home run in the loss.

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Minnesota Twins vs Cleveland Guardians Form

Table

Teams Pts P W L
11 Cleveland Guardians
0.525 162 85 77
19 Minnesota Twins
0.475 162 77 85

Minnesota Twins and Cleveland Guardians Latest Matches

Minnesota Twins
Minnesota Twins Latest matches
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 9, 2026 - MLB

Detroit Tigers
7 :  2
Minnesota Twins

Sep 8, 2026 - MLB

Detroit Tigers
2 :  3
Minnesota Twins

Sep 7, 2026 - MLB

Detroit Tigers
5 :  4
Minnesota Twins

Sep 6, 2026 - MLB

Chicago White Sox
10 :  1
Minnesota Twins

Sep 5, 2026 - MLB

Chicago White Sox
4 :  6
Minnesota Twins

Sep 4, 2026 - MLB

Chicago White Sox
4 :  1
Minnesota Twins
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 2, 2026 - MLB

Minnesota Twins
6 :  11
Detroit Tigers

Sep 1, 2026 - MLB

Minnesota Twins
15 :  2
Detroit Tigers

Aug 31, 2026 - MLB

Minnesota Twins
11 :  1
Detroit Tigers

Aug 30, 2026 - MLB

Minnesota Twins
5 :  1
Chicago White Sox

Aug 29, 2026 - MLB

Minnesota Twins
2 :  3
Chicago White Sox

Aug 28, 2026 - MLB

Minnesota Twins
4 :  7
Chicago White Sox
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 9, 2026 - MLB

Detroit Tigers
7 :  2
Minnesota Twins

Sep 8, 2026 - MLB

Detroit Tigers
2 :  3
Minnesota Twins

Sep 7, 2026 - MLB

Detroit Tigers
5 :  4
Minnesota Twins

Sep 6, 2026 - MLB

Chicago White Sox
10 :  1
Minnesota Twins

Sep 5, 2026 - MLB

Chicago White Sox
4 :  6
Minnesota Twins

Sep 4, 2026 - MLB

Chicago White Sox
4 :  1
Minnesota Twins
Cleveland Guardians
Cleveland Guardians Latest matches
W L W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 9, 2026 - MLB

Baltimore Orioles
9 :  5
Cleveland Guardians

Sep 8, 2026 - MLB

Baltimore Orioles
5 :  9
Cleveland Guardians

Sep 7, 2026 - MLB

Baltimore Orioles
6 :  4
Cleveland Guardians

Sep 6, 2026 - MLB

Cleveland Guardians
3 :  2
Detroit Tigers

Sep 5, 2026 - MLB

Cleveland Guardians
0 :  6
Detroit Tigers

Sep 4, 2026 - MLB

Cleveland Guardians
4 :  3
Detroit Tigers
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 6, 2026 - MLB

Cleveland Guardians
3 :  2
Detroit Tigers

Sep 5, 2026 - MLB

Cleveland Guardians
0 :  6
Detroit Tigers

Sep 4, 2026 - MLB

Cleveland Guardians
4 :  3
Detroit Tigers

Sep 4, 2026 - MLB

Cleveland Guardians
7 :  6
Detroit Tigers

Sep 3, 2026 - MLB

Cleveland Guardians
3 :  6
Toronto Blue Jays

Sep 2, 2026 - MLB

Cleveland Guardians
0 :  11
Toronto Blue Jays
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 9, 2026 - MLB

Baltimore Orioles
9 :  5
Cleveland Guardians

Sep 8, 2026 - MLB

Baltimore Orioles
5 :  9
Cleveland Guardians

Sep 7, 2026 - MLB

Baltimore Orioles
6 :  4
Cleveland Guardians

Aug 26, 2026 - MLB

Los Angeles Angels
3 :  4
Cleveland Guardians

Aug 25, 2026 - MLB

Los Angeles Angels
6 :  8
Cleveland Guardians

Aug 24, 2026 - MLB

Los Angeles Angels
2 :  4
Cleveland Guardians

Minnesota Twins against Cleveland Guardians : Head to Head (H2H)

Minnesota Twins

50 %

Cleveland Guardians

50 %

Jul 23, 2026 - MLB

Cleveland Guardians
1 :  3
Minnesota Twins

Jul 22, 2026 - MLB

Cleveland Guardians
6 :  10
Minnesota Twins

Jul 21, 2026 - MLB

Cleveland Guardians
5 :  2
Minnesota Twins

Jul 20, 2026 - MLB

Cleveland Guardians
13 :  4
Minnesota Twins

Jul 9, 2026 - MLB

Minnesota Twins
2 :  5
Cleveland Guardians

Jul 8, 2026 - MLB

Minnesota Twins
6 :  5
Cleveland Guardians
Minnesota Twins vs Cleveland Guardians Picks

Minnesota Twins - Cleveland Guardians Key Points

  1. Guardians' collective slugging percentage is the worst in MLB at .372
  2. Guardians' collective ERA is seventh-best in MLB at 3.81
  3. Twins have a 38-34 record at Target Field this season
  4. Guardians' pitching staff has a 9-to-knuckle ratio that is third-best in MLB

Our Minnesota Twins vs Cleveland Guardians Prediction

Taj Bradley will start the first game of this series for the Twins, boasting impressive career numbers against Cleveland, against whom he has a 1.48 ERA. On July 23, at Progressive Field, Bradley pitched seven innings, allowing only one run against the Guards.

For now, the Guards enter this critical stage of the season with their star player in a slump; Ramírez is batting .125 and has not recorded an extra-base hit in his last eight games.

Our prediction for Twins vs Guardians is: Under 7.5 runs.

Prediction:

 

Under 7.5 points

−105
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.