Kansas City Royals vs Cleveland Guardians Prediction & Picks - MLB
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by Matt Lowrimore | in MLB Picks
Every team will be in action for Wednesday’s 15-game MLB slate, one of which will include an AL Central matchup between the Kansas City Royals and the Cleveland Guardians. Let’s take a look at the match statistics and predictions for this game between the Royals and the Guardians.
Kansas City extended its win streak to five games on Tuesday and is now just two games under .500 at 17-19. Starting this game for the Royals in Game 3 will be Cole Ragans. He comes into this game with a record of 1-4 and has an ERA of 5.29. That being said, Ragans has almost been unhittable at home, a trend that could continue against the slumping Guardians.
As for Cleveland, they have now lost three games in a row and will look to bounce back in Game 3 of this series by starting Joey Cantillo. He comes into this game with a record of 1-1 and an ERA of 3.67. Most of his struggles have been on the road this season, suggesting he could struggle against the red-hot Royals.
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Kansas City Royals vs Cleveland Guardians Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
10
|
0.519 | 81 | 42 | 39 |
|
26
|
0.425 | 80 | 34 | 46 |
Kansas City Royals and Cleveland Guardians Latest Matches
5/6 (83%)
1/6 (17%)
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5/6 (83%)
1/6 (17%)
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4/6 (67%)
2/6 (33%)
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3/6 (50%)
3/6 (50%)
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2/6 (33%)
4/6 (67%)
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2/6 (33%)
4/6 (67%)
May 5, 2026 - MLB
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Kansas City Royals against Cleveland Guardians : Head to Head (H2H)
50 %
50 %
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Mar 19, 2026 - MLB Spring Training
Kansas City Royals - Cleveland Guardians Key Points
- Joey Cantillo has an ERA of 3.67 this season
- Joey Cantillo has an ERA of 4.34 on the road this season
- Cole Ragans has an ERA of 5.29 this season
- Cole Ragans has an ERA of 0.75 at home this season
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Our Kansas City Royals vs Cleveland Guardians Prediction
The Royals are favored in this game; however, they look to be the best betting option. The Royals are currently tied for the second-longest winning streak in the league and have Ragans on the mound, who, as mentioned, has been elite at home this season. In two home starts, Ragans has allowed two runs (one earned) over 12.0 innings.
Cantillo, on the other hand, has made four road starts, allowing 11 runs (nine earned) over 20.0 innings. On top of that, the Royals’ offense has been averaging 5.0 runs per game during their winning streak, while the Guardians are averaging 2.0 runs per game during their losing streak. Given that, our Kansas City Royals vs Cleveland Guardians prediction is: Kansas City Royals ML.All tips are fully researched and given in good faith, but profits cannot be guaranteed.