Detroit Tigers vs Cleveland Guardians Prediction & Picks - MLB
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by Lou Aguila | in MLB Picks
The Cleveland Guardians have won by at least two runs in 7 of their last 10 matches with the Detroit Tigers. The Guardians are currently trading at +126 to cover -1.5 runs in Wednesday’s series finale.
The Cleveland Guardians will march into Wednesday’s series finale against the Detroit Tigers as -130 favorites after winning the first two games of this mid-week AL Central duel.
Behind another stellar game from the bullpen, the Guardians edged the Tigers 4-3 in Game 2 after routing them 8-2 in the series opener. Cleveland’s firemen command a solid 3.86 ERA this season, but they managed to lower it to 3.00 ERA over their last five games.
Meanwhile, the Tigers have lost their last four games, plunging 9 games below .500 at 20-29. Caesars has posted Detroit as +110 home underdogs and -150 on the +1.5 line.
Detroit’s ERA jumped to 4.12 in the season to 4.70 over the last five games, aggravated by the 18 earned runs they gave up in their last four assignments. Worse, the Tigers’ offense only averages 2.0 runs per game while batting .198 during this five-game stretch.
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Detroit Tigers vs Cleveland Guardians Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
16
|
0.492 | 118 | 58 | 60 |
|
19
|
0.487 | 119 | 58 | 61 |
Detroit Tigers and Cleveland Guardians Latest Matches
1/6 (17%)
5/6 (83%)
May 19, 2026 - MLB
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1/6 (17%)
5/6 (83%)
May 19, 2026 - MLB
May 18, 2026 - MLB
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1/6 (17%)
5/6 (83%)
May 14, 2026 - MLB
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May 8, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 19, 2026 - MLB
May 18, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
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May 13, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
May 11, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 19, 2026 - MLB
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May 4, 2026 - MLB
Detroit Tigers against Cleveland Guardians : Head to Head (H2H)
50 %
50 %
May 19, 2026 - MLB
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Detroit Tigers - Cleveland Guardians Key Points
- Cleveland is 7-1 SU in its last 8 games.
- Cleveland is 8-3 SU in its last 11 games against Detroit.
- Detroit is 1-7 SU in its last 8 games.
- Detroit is 0-5 SU in its last 5 games when playing at home against Cleveland.
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Our Detroit Tigers vs Cleveland Guardians Prediction
Fearless Forecast: Guardians complete sweep of the Tigers.
Despite going 0-5 with a 3.58 ERA in his last five starts, Tanner Bibee remains in a good spot to lead the Guardians to a win here because of his history of success facing the Tigers.
Bibee allowed only one earned run in each of his last three starts against Detroit. In his latest start against the Tigers on October 1, 2025, Bibee conceded one earned run over 4.2 innings to power Cleveland to a 6-1 win.
Detroit hasn’t announced its starter for this series finale. Regardless of which starter they will send to the mound, the Tigers cannot win this game if they continue to score no more than two runs per game.
Also, even if they can get into Bibee this time around, Detroit’s batters will need to figure out how to hit Cleveland’s relief pitchers, who have done a great job shutting them down in the late innings of this series.
The Guardians have won 7 of their last 10 meetings with the Tigers, winning by at least two runs in each of these victories.
Our betting prediction for the Cleveland Guardians vs. the Detroit Tigers: The Guardians -1.5 Runs
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