Detroit Tigers vs Cleveland Guardians Prediction & Picks - MLB
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by Lou Aguila | in MLB Picks
The Cleveland Guardians, 6-1 in their last 7 games, head to Detroit seeking another road win over the struggling Tigers in Game 1 of their series on Monday.
Momentum: The Cleveland Guardians (26-22) have won five of their last six games, including the final two games against the Cincinnati Reds to claim the series win.
On the contrary, the Detroit Tigers (20-27) have lost five of their last six games and 10 of their last 12 games. They are currently tied with the Kansas City Royals (20-27) with the worst record in the American League Central division.
The Matchup: The Guardians have won 6 of their last 10 meetings with the Tigers, but Detroit has won 3 of the last 4.
Guardians right-handed pitcher Slade Cecconi (2-4, 5.60 ERA) will duke it out with Tigers’ lefty Framber Valdez (2-2, 4.32 ERA). Cecconi blanked the LA Angeles through 4 innings in his last start on May 12. Valdez has lost 3 of his last 4 starts, including his last mound appearance in which he allowed two earned runs over 6.2 innings in a 2-3 loss to the Mets.
Hot on the Board: The Guardians are generating significant interest from sports bettors after catching a +122 moneyline price despite their terrific showing as of late. 13-8 at home this season, the Tigers are -145 to win and +143 to cover -1.5 runs.
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Detroit Tigers vs Cleveland Guardians Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
16
|
0.492 | 118 | 58 | 60 |
|
19
|
0.487 | 119 | 58 | 61 |
Detroit Tigers and Cleveland Guardians Latest Matches
1/6 (17%)
5/6 (83%)
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 14, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
1/6 (17%)
5/6 (83%)
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 6, 2026 - MLB
May 5, 2026 - MLB
May 4, 2026 - MLB
1/6 (17%)
5/6 (83%)
May 14, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
May 10, 2026 - MLB
May 9, 2026 - MLB
May 8, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
May 11, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
May 11, 2026 - MLB
3/6 (50%)
3/6 (50%)
May 7, 2026 - MLB
May 6, 2026 - MLB
May 5, 2026 - MLB
May 4, 2026 - MLB
May 3, 2026 - MLB
May 2, 2026 - MLB
Detroit Tigers against Cleveland Guardians : Head to Head (H2H)
50 %
50 %
Oct 2, 2025 - MLB
Oct 1, 2025 - MLB
Sep 30, 2025 - MLB
Sep 25, 2025 - MLB
Sep 24, 2025 - MLB
Sep 23, 2025 - MLB
Detroit Tigers - Cleveland Guardians Key Points
- Cleveland is 5-1 SU in its last 6 games.
- Cleveland is 7-1 SU in its last 8 games when playing on the road against Detroit.
- Detroit is 1-5 SU in its last 6 games.
- Detroit is 1-7 SU in its last 8 games when playing at home against Cleveland.
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Our Detroit Tigers vs Cleveland Guardians Prediction
Fearless Forecast: The Guardians stay hot, outgun the Tigers in Game 1.
Smart Play: Bet on the Guardians at +122 moneyline. Cleveland can sustain this momentum because of their prolific offense, which has generated 6.6 runs per game at a .265 batting average over the last five games. On the other hand, the Tigers have only averaged 2.1 runs per game on a .210 BA in their last five assignments.
Cade Cecconi has only allowed four earned runs across three mound appearances against the Tigers last season. Framber Valdez delivered a no-hitter the last time he faced the Guardians on August 1, 2023, but it’s unlikely he will come up with a performance similar to that as he has been erratic this season.
Our betting prediction for the Cleveland Guardians vs. the Detroit Tigers: The Guardians will win.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
