Detroit Tigers vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Detroit Tigers
5/22/25 18:40
Cleveland Guardians

Prediction:

 

Tigers -1.5 Runs

+165
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 by Lou Aguila | in MLB Picks

The Detroit Tigers and the Cleveland Guardians kick off their 4-game weekend series on Thursday at Comerica Park.

The Tigers have won 3 of their last 4 games, including the final two matches of their series against the St. Louis Cardinals, to improve their regular-slate to 33-17, No.1 in the AL Central standings. Detroit is still churning out terrific numbers from the mound, pitching a 3.32 ERA and 1.16 WHIP this season.

The Guardians snapped a 5-game skid with a 5-1 win over the Minnesota Twins on Wednesday. Cleveland are fourth in the AL Central standings with a 26-22 record, 6 games behind the Tigers. Over their last five games, the Guardians are averaging 3.2 runs per game and a 3.89 ERA.

Detroit Tigers vs Cleveland Guardians Form

Table

Teams Pts P W L
10 Cleveland Guardians
0.543 162 88 74
11 Detroit Tigers
0.537 162 87 75

Detroit Tigers and Cleveland Guardians Latest Matches

Detroit Tigers
Detroit Tigers Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

May 21, 2025 - MLB

St. Louis Cardinals
1 :  5
Detroit Tigers

May 20, 2025 - MLB

St. Louis Cardinals
4 :  5
Detroit Tigers

May 14, 2025 - MLB

Detroit Tigers
6 :  5
Boston Red Sox

May 9, 2025 - MLB

Detroit Tigers
2 :  1
Texas Rangers

May 2, 2025 - MLB

Los Angeles Angels
1 :  9
Detroit Tigers

May 1, 2025 - MLB

Los Angeles Angels
4 :  10
Detroit Tigers
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 14, 2025 - MLB

Detroit Tigers
6 :  5
Boston Red Sox

May 9, 2025 - MLB

Detroit Tigers
2 :  1
Texas Rangers

Apr 27, 2025 - MLB

Detroit Tigers
7 :  0
Baltimore Orioles

Apr 26, 2025 - MLB

Detroit Tigers
4 :  3
Baltimore Orioles

Apr 23, 2025 - MLB

Detroit Tigers
6 :  0
San Diego Padres

Apr 22, 2025 - MLB

Detroit Tigers
0 :  2
San Diego Padres
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 21, 2025 - MLB

St. Louis Cardinals
1 :  5
Detroit Tigers

May 20, 2025 - MLB

St. Louis Cardinals
4 :  5
Detroit Tigers

May 2, 2025 - MLB

Los Angeles Angels
1 :  9
Detroit Tigers

May 1, 2025 - MLB

Los Angeles Angels
4 :  10
Detroit Tigers

Apr 30, 2025 - MLB

Houston Astros
4 :  7
Detroit Tigers

Apr 29, 2025 - MLB

Houston Astros
6 :  4
Detroit Tigers
Cleveland Guardians
Cleveland Guardians Latest matches
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 21, 2025 - MLB

Minnesota Twins
1 :  5
Cleveland Guardians

May 13, 2025 - MLB

Cleveland Guardians
2 :  0
Milwaukee Brewers

May 10, 2025 - MLB

Cleveland Guardians
1 :  7
Philadelphia Phillies

May 7, 2025 - MLB

Washington Nationals
6 :  8
Cleveland Guardians

May 4, 2025 - MLB

Toronto Blue Jays
4 :  5
Cleveland Guardians

May 3, 2025 - MLB

Toronto Blue Jays
3 :  5
Cleveland Guardians
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 13, 2025 - MLB

Cleveland Guardians
2 :  0
Milwaukee Brewers

May 10, 2025 - MLB

Cleveland Guardians
1 :  7
Philadelphia Phillies

May 1, 2025 - MLB

Cleveland Guardians
4 :  3
Minnesota Twins

Apr 30, 2025 - MLB

Cleveland Guardians
4 :  2
Minnesota Twins

Apr 29, 2025 - MLB

Cleveland Guardians
2 :  1
Minnesota Twins

Apr 28, 2025 - MLB

Cleveland Guardians
1 :  11
Minnesota Twins
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 21, 2025 - MLB

Minnesota Twins
1 :  5
Cleveland Guardians

May 7, 2025 - MLB

Washington Nationals
6 :  8
Cleveland Guardians

May 4, 2025 - MLB

Toronto Blue Jays
4 :  5
Cleveland Guardians

May 3, 2025 - MLB

Toronto Blue Jays
3 :  5
Cleveland Guardians

May 2, 2025 - MLB

Toronto Blue Jays
5 :  3
Cleveland Guardians

Apr 20, 2025 - MLB

Pittsburgh Pirates
4 :  5
Cleveland Guardians

Detroit Tigers against Cleveland Guardians : Head to Head (H2H)

Detroit Tigers

33 %

Cleveland Guardians

67 %

Oct 12, 2024 - MLB

Cleveland Guardians
7 :  3
Detroit Tigers

Oct 10, 2024 - MLB

Detroit Tigers
4 :  5
Cleveland Guardians

Oct 9, 2024 - MLB

Detroit Tigers
3 :  0
Cleveland Guardians

Oct 7, 2024 - MLB

Cleveland Guardians
0 :  3
Detroit Tigers

Oct 5, 2024 - MLB

Cleveland Guardians
7 :  0
Detroit Tigers

Jul 29, 2024 - MLB

Detroit Tigers
4 :  8
Cleveland Guardians

Detroit Tigers - Cleveland Guardians Key Points

  1. Detroit is 8-2 SU in its last 10 games against an opponent in the American League Central Division
  2. Detroit is 7-2 SU in its last 9 games.
  3. Cleveland is 1-4 SU in its last 5 games.
  4. Cleveland is 5-2 SU in its last 7 games against Detroit.

Our Detroit Tigers vs Cleveland Guardians Prediction

Fearless Forecast: Tigers take first game of the series vs. the Guardians

Why we should bet on the Tigers to cover -1.5 runs: Apart from their 17-5 record at Comerica Park this season, the Tigers are sending in Guardians killer Jack Flaherty, who has allowed zero earned runs in his last two starts vs. Cleveland. The Tigers are batting 5.4 runs per game on a .259 batting average at home this season, which could be bad news for Guardians starter Tanner Bibee. Bibee allowed 4 earned runs in 4-5 loss to the Cincinnati Reds in his last start on May 16. Cleveland is 1-4 SU in its last 5 games, while Detroit is 8-2 SU in its last 10 games against an American League Central Division opponent.

Our betting prediction for the Detroit Tigers vs. the Cleveland Guardians: Tigers -1.5 runs

Prediction:

 

Tigers -1.5 Runs

+165
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Detroit Tigers vs Cleveland Guardians Picks