Cincinnati Reds vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Cincinnati Reds
7/27/26 19:10
Cleveland Guardians

Prediction:

 

Reds ML

+118
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 by Travis Pulver | in MLB Picks

The Cleveland Guardians (54-53, 27-27 Away) will try to bring their losing streak to an end today when they visit the Cincinnati Reds. Game time at Great American Ball Park in Cincinnati, OH, is scheduled for 7 p.m. EST with coverage provided by ESPN.

They had a really good shot at ending it yesterday in the series finale with the Tampa Bay Rays. But while Parker Messick threw a solid game from the mound, the lineup went quiet, and they lost, 1-0, extending the losing streak to five games.

Slade Cecconi is scheduled to get the start for the Guardians. He has gone 4-7 in 20 starts with a 4.60 ERA and a 1.45 WHIP. Cecconi has gone 3-5 in 12 road starts with a 4.81 ERA and a .280 OBA. In his last three starts, he has allowed at least three earned runs per game.

Cincinnati will turn to Chase Burns on the mound. Burns has gone 12-1 in 19 starts with a 2.42 ERA and a 1.11 WHIP. He has pitched well at home this season, where he is 6-1 in nine starts with a 2.32 ERA and a .190 OBA. In his last home start, he went five innings against the Phillies, gave up three hits and earned runs while walking six.

Cincinnati Reds vs Cleveland Guardians Form

Table

Teams Pts P W L
13 Cleveland Guardians
0.505 107 54 53
23 Cincinnati Reds
0.471 104 49 55

Cincinnati Reds and Cleveland Guardians Latest Matches

Cincinnati Reds
Cincinnati Reds Latest matches
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 26, 2026 - MLB

St. Louis Cardinals
3 :  5
Cincinnati Reds

Jul 25, 2026 - MLB

St. Louis Cardinals
7 :  0
Cincinnati Reds

Jul 24, 2026 - MLB

St. Louis Cardinals
2 :  4
Cincinnati Reds

Jul 22, 2026 - MLB

Seattle Mariners
3 :  5
Cincinnati Reds

Jul 21, 2026 - MLB

Seattle Mariners
2 :  4
Cincinnati Reds

Jul 20, 2026 - MLB

Seattle Mariners
8 :  0
Cincinnati Reds
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 12, 2026 - MLB

Cincinnati Reds
4 :  8
Chicago Cubs

Jul 11, 2026 - MLB

Cincinnati Reds
3 :  5
Chicago Cubs

Jul 10, 2026 - MLB

Cincinnati Reds
4 :  0
Chicago Cubs

Jul 9, 2026 - MLB

Cincinnati Reds
0 :  1
Philadelphia Phillies

Jul 8, 2026 - MLB

Cincinnati Reds
11 :  5
Philadelphia Phillies

Jul 7, 2026 - MLB

Cincinnati Reds
1 :  4
Philadelphia Phillies
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 26, 2026 - MLB

St. Louis Cardinals
3 :  5
Cincinnati Reds

Jul 25, 2026 - MLB

St. Louis Cardinals
7 :  0
Cincinnati Reds

Jul 24, 2026 - MLB

St. Louis Cardinals
2 :  4
Cincinnati Reds

Jul 22, 2026 - MLB

Seattle Mariners
3 :  5
Cincinnati Reds

Jul 21, 2026 - MLB

Seattle Mariners
2 :  4
Cincinnati Reds

Jul 20, 2026 - MLB

Seattle Mariners
8 :  0
Cincinnati Reds
Cleveland Guardians
Cleveland Guardians Latest matches
W L L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Jul 26, 2026 - MLB

Tampa Bay Rays
1 :  0
Cleveland Guardians

Jul 25, 2026 - MLB

Tampa Bay Rays
3 :  0
Cleveland Guardians

Jul 24, 2026 - MLB

Tampa Bay Rays
11 :  3
Cleveland Guardians

Jul 23, 2026 - MLB

Cleveland Guardians
1 :  3
Minnesota Twins

Jul 22, 2026 - MLB

Cleveland Guardians
6 :  10
Minnesota Twins

Jul 21, 2026 - MLB

Cleveland Guardians
5 :  2
Minnesota Twins
W L W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 23, 2026 - MLB

Cleveland Guardians
1 :  3
Minnesota Twins

Jul 22, 2026 - MLB

Cleveland Guardians
6 :  10
Minnesota Twins

Jul 21, 2026 - MLB

Cleveland Guardians
5 :  2
Minnesota Twins

Jul 20, 2026 - MLB

Cleveland Guardians
13 :  4
Minnesota Twins

Jul 19, 2026 - MLB

Cleveland Guardians
1 :  7
Pittsburgh Pirates

Jul 18, 2026 - MLB

Cleveland Guardians
5 :  3
Pittsburgh Pirates
W W W L L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 26, 2026 - MLB

Tampa Bay Rays
1 :  0
Cleveland Guardians

Jul 25, 2026 - MLB

Tampa Bay Rays
3 :  0
Cleveland Guardians

Jul 24, 2026 - MLB

Tampa Bay Rays
11 :  3
Cleveland Guardians

Jul 12, 2026 - MLB

Miami Marlins
2 :  5
Cleveland Guardians

Jul 11, 2026 - MLB

Miami Marlins
1 :  4
Cleveland Guardians

Jul 10, 2026 - MLB

Miami Marlins
2 :  3
Cleveland Guardians

Cincinnati Reds against Cleveland Guardians : Head to Head (H2H)

Cincinnati Reds

17 %

Cleveland Guardians

83 %

May 17, 2026 - MLB

Cleveland Guardians
10 :  3
Cincinnati Reds

May 16, 2026 - MLB

Cleveland Guardians
7 :  4
Cincinnati Reds

May 15, 2026 - MLB

Cleveland Guardians
6 :  7
Cincinnati Reds

Mar 22, 2026 - MLB Spring Training

Cleveland Guardians
8 :  2
Cincinnati Reds

Mar 17, 2026 - MLB Spring Training

Cincinnati Reds
6 :  8
Cleveland Guardians

Feb 21, 2026 - MLB Spring Training

Cleveland Guardians
4 :  2
Cincinnati Reds
Cincinnati Reds vs Cleveland Guardians Picks

Cincinnati Reds - Cleveland Guardians Key Points

  1. Cleveland leads the all-time series vs. the Reds, 79-65.
  2. Cincinnati is 24-26 ATS (run line) at home; Cleveland is 29-25 ATS (run line) on the road.
  3. The OVER is 23-32 for the Guardians on the road and 27-23 for the Reds at home.
  4. Betting Public: 18% of run line tickets and 71% of the handle are on the Reds.

Our Cincinnati Reds vs Cleveland Guardians Prediction

Cleveland has been the better team this season. But they have not been playing well of late, hence the five-game losing streak. The lineup has been hitting just .235 over the last week and scored 28 runs across seven games. I don’t see this lineup exploding against a solid pitcher like Burns, who has given up just ten hits all month (three starts). However, the Reds lineup has been struggling at the plate as well (.201 over the last week; 18 runs scored across six games). If you want a cautious approach, take the Reds moneyline. But I’m betting that several of the Reds hitters are due and that Burns will lock the Guardians lineup down.

Our Cleveland vs. Cincinnati Pick: Reds -1.5

Prediction:

 

Reds ML

+118
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.