Boston Red Sox vs Cleveland Guardians Prediction & Picks - MLB
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by Lou Aguila | in MLB Picks
The Boston Red Sox will turn to one of their most consistent pitchers this season, Sonny Gray, to end the Guardians’ 6-game winning streak and cover -1.5 runs (+163) in Game 2 of their series.
Current Form:
The Cleveland Guardians (82-75) have won their last 6 games to stay ahead of the Chicago White Sox (81-76) by one game in the AL Central title race. The Guardians have registered a 2.80 ERA and averaged 5.9 runs over their last five games.
The Boston Red Sox have already clinched a wild card spot despite losing their last three games. The 84-73 Red Sox have a 3-game lead over the 81-76 Chicago White Sox in the AL card race, guaranteeing at least 3 postseason teams from the AL East.
Starting Pitchers: Red Sox RHP Sonny Gray (17-5, 2.82 ERA) vs. Guardians LHP Foster Griffin (15-5, 3.72 ERA).
The Matchup: The Red Sox have won 6 of their last 9 meetings with the Guardians.
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Boston Red Sox vs Cleveland Guardians Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
9
|
0.537 | 162 | 87 | 75 |
|
11
|
0.525 | 162 | 85 | 77 |
Boston Red Sox and Cleveland Guardians Latest Matches
2/6 (33%)
4/6 (67%)
Sep 22, 2026 - MLB
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2/6 (33%)
4/6 (67%)
Sep 22, 2026 - MLB
Sep 13, 2026 - MLB
Sep 12, 2026 - MLB
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Sep 8, 2026 - MLB
2/6 (33%)
4/6 (67%)
Sep 20, 2026 - MLB
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Sep 18, 2026 - MLB
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Sep 15, 2026 - MLB
6/6 (100%)
0/6 (0%)
Sep 22, 2026 - MLB
Sep 20, 2026 - MLB
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Sep 15, 2026 - MLB
5/6 (83%)
1/6 (17%)
Sep 20, 2026 - MLB
Sep 19, 2026 - MLB
Sep 18, 2026 - MLB
Sep 16, 2026 - MLB
Sep 15, 2026 - MLB
Sep 14, 2026 - MLB
4/6 (67%)
2/6 (33%)
Sep 22, 2026 - MLB
Sep 13, 2026 - MLB
Sep 12, 2026 - MLB
Sep 11, 2026 - MLB
Sep 9, 2026 - MLB
Sep 8, 2026 - MLB
Boston Red Sox against Cleveland Guardians : Head to Head (H2H)
67 %
33 %
Sep 22, 2026 - MLB
May 31, 2026 - MLB
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May 29, 2026 - MLB
Sep 2, 2025 - MLB
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Boston Red Sox - Cleveland Guardians Key Points
- The Red Sox are 5-0 in Gray’s last 5 home starts vs. a team with a winning record.
- The Red Sox are 41-40 in their road games against the spread
- The Guardians are 3-2 in their last 5 games against the spread
- The Guardians are 4-6 in their last 10 games against the Red Sox.
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Our Boston Red Sox vs Cleveland Guardians Prediction
Key Stats: Gray has won her last three starts against the Guardians. The Red Sox hurler has not allowed more than three runs in any of his last three starts against Cleveland.
In his last face-off against the Guardians, Gray surrendered one run over 6.0 innings in the Red Sox’s 9-1 win on May 30, 2026.
What to Expect: Gray will help the Red Sox snap the Guardians’ 6-game winning streak. Gray will stifle the Guardians’ batting lineup anew, allowing the Red Sox to get a head start and giving its bullpen (1.64 ERA over the last five games) a significant lead to protect in the final innings.
Fearless Forecast: The Red Sox 5, the Guardians 2
Our betting prediction for the Boston Red Sox vs. the Cleveland Guardians: The Red Sox -1.5 Runs
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