Boston Red Sox vs Cleveland Guardians Prediction & Picks - MLB

Prediction published on 9/1/25, 9:54 AM  by Travis Pulver | Modified on 1/13/26 at 9:16 AM in MLB Picks

The Cleveland Guardians will head out to the East Coast for a three-game series with the Red Sox in Boston, with Game One scheduled for today at 1:35 p.m. EST at Fenway Park.

Cleveland saw its four-game win streak come to an end yesterday with a 4-2 loss to the Seattle Mariners at home. With that loss, they are 68-67, four games back of the Mariners for the final wild card spot in the AL. Boston lost two of three to the Pirates at home over the weekend. At 76-62, they have a 2.5-game lead on the Mariners for the second AL-wild-card spot. Parker Messick is scheduled to make his third career start today for the Guardians. So far, he’s had one road start and one at home. Between the two, he has surrendered one earned run (.66 ERA), 11 hits, and one walk (.88 WHIP), and 11 hits (no homeruns) for a .224 OBA. Boston will go with Brayan Bello. Bello has gone 10-6 this season in 23 starts (24 appearances) with a 2.99 ERA, 1.21 WHIP, and a .237 OBA. He’s gone 7-3 at home in 14 starts (15 appearances) with a 3.07 ERA and .245 OBA.