Baltimore Orioles vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Baltimore Orioles
9/9/26 18:35
Cleveland Guardians

Prediction:

 

Under 9 Total Runs

-120
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 by Matt Lowrimore in MLB Picks

A full 15-game MLB slate is scheduled for Wednesday, one of which will include an American League matchup between the Baltimore Orioles and the Cleveland Guardians. Let’s take a look at the match statistics and predictions for this game between the Orioles and the Guardians.

Cleveland enters this game hovering at .500, but despite that, is currently in second place in the American League Central Division. Set to start Game 2 of this series for the Guardians will be Foster Griffin, who has an ERA of 3.26. Griffin has also been more than serviceable on the road this season, suggesting he will be able to continue his success against the Orioles.

As for Baltimore, they enter this matchup several games under .500 and are currently in last place in the American League East Division. Starting this game for the Orioles will be Shane Baz, who has an ERA of 3.91. Baz has had most of his success at home this season, further suggesting runs could be limited.

Baltimore Orioles vs Cleveland Guardians Form

Table

Teams Pts P W L
13 Cleveland Guardians
0.507 146 74 72
19 Baltimore Orioles
0.479 146 70 76

Baltimore Orioles and Cleveland Guardians Latest Matches

Baltimore Orioles
Baltimore Orioles Latest matches
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Sep 8, 2026 - MLB

Baltimore Orioles
5 :  9
Cleveland Guardians

Sep 7, 2026 - MLB

Baltimore Orioles
6 :  4
Cleveland Guardians

Sep 6, 2026 - MLB

Baltimore Orioles
1 :  3
Boston Red Sox

Sep 5, 2026 - MLB

Baltimore Orioles
0 :  5
Boston Red Sox

Sep 4, 2026 - MLB

Baltimore Orioles
0 :  1
Boston Red Sox

Sep 3, 2026 - MLB

Baltimore Orioles
5 :  6
Boston Red Sox
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Sep 8, 2026 - MLB

Baltimore Orioles
5 :  9
Cleveland Guardians

Sep 7, 2026 - MLB

Baltimore Orioles
6 :  4
Cleveland Guardians

Sep 6, 2026 - MLB

Baltimore Orioles
1 :  3
Boston Red Sox

Sep 5, 2026 - MLB

Baltimore Orioles
0 :  5
Boston Red Sox

Sep 4, 2026 - MLB

Baltimore Orioles
0 :  1
Boston Red Sox

Sep 3, 2026 - MLB

Baltimore Orioles
5 :  6
Boston Red Sox
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 2, 2026 - MLB

Colorado Rockies
6 :  5
Baltimore Orioles

Sep 1, 2026 - MLB

Colorado Rockies
4 :  2
Baltimore Orioles

Aug 31, 2026 - MLB

Colorado Rockies
1 :  2
Baltimore Orioles

Aug 30, 2026 - MLB

Athletics
5 :  8
Baltimore Orioles

Aug 29, 2026 - MLB

Athletics
3 :  5
Baltimore Orioles

Aug 28, 2026 - MLB

Athletics
3 :  4
Baltimore Orioles
Cleveland Guardians
Cleveland Guardians Latest matches
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 8, 2026 - MLB

Baltimore Orioles
5 :  9
Cleveland Guardians

Sep 7, 2026 - MLB

Baltimore Orioles
6 :  4
Cleveland Guardians

Sep 6, 2026 - MLB

Cleveland Guardians
3 :  2
Detroit Tigers

Sep 5, 2026 - MLB

Cleveland Guardians
0 :  6
Detroit Tigers

Sep 4, 2026 - MLB

Cleveland Guardians
4 :  3
Detroit Tigers

Sep 4, 2026 - MLB

Cleveland Guardians
7 :  6
Detroit Tigers
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 6, 2026 - MLB

Cleveland Guardians
3 :  2
Detroit Tigers

Sep 5, 2026 - MLB

Cleveland Guardians
0 :  6
Detroit Tigers

Sep 4, 2026 - MLB

Cleveland Guardians
4 :  3
Detroit Tigers

Sep 4, 2026 - MLB

Cleveland Guardians
7 :  6
Detroit Tigers

Sep 3, 2026 - MLB

Cleveland Guardians
3 :  6
Toronto Blue Jays

Sep 2, 2026 - MLB

Cleveland Guardians
0 :  11
Toronto Blue Jays
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 8, 2026 - MLB

Baltimore Orioles
5 :  9
Cleveland Guardians

Sep 7, 2026 - MLB

Baltimore Orioles
6 :  4
Cleveland Guardians

Aug 26, 2026 - MLB

Los Angeles Angels
3 :  4
Cleveland Guardians

Aug 25, 2026 - MLB

Los Angeles Angels
6 :  8
Cleveland Guardians

Aug 24, 2026 - MLB

Los Angeles Angels
2 :  4
Cleveland Guardians

Aug 23, 2026 - MLB

Colorado Rockies
2 :  7
Cleveland Guardians

Baltimore Orioles against Cleveland Guardians : Head to Head (H2H)

Baltimore Orioles

33 %

Cleveland Guardians

67 %

Sep 8, 2026 - MLB

Baltimore Orioles
5 :  9
Cleveland Guardians

Sep 7, 2026 - MLB

Baltimore Orioles
6 :  4
Cleveland Guardians

Apr 19, 2026 - MLB

Cleveland Guardians
8 :  4
Baltimore Orioles

Apr 18, 2026 - MLB

Cleveland Guardians
4 :  2
Baltimore Orioles

Apr 17, 2026 - MLB

Cleveland Guardians
4 :  6
Baltimore Orioles

Apr 16, 2026 - MLB

Cleveland Guardians
4 :  2
Baltimore Orioles
Baltimore Orioles vs Cleveland Guardians Picks

Baltimore Orioles - Cleveland Guardians Key Points

  1. Foster Griffin has an ERA of 3.26 this season
  2. Foster Griffin has an ERA of 3.14 on the road this season
  3. Shane Baz has an ERA of 3.91 this season
  4. Shane Baz has an ERA of 3.63 at home this season

Our Baltimore Orioles vs Cleveland Guardians Prediction

Baltimore is the small favorite in this matchup; however, the under looks to be the best betting option. This goes directly to the home/away splits between the two starting pitchers. Griffin has made 14 away starts this season, in which he has allowed 32 runs (28 earned) over 80.1 innings. Baz, on the other hand, has made 14 home starts, where he has allowed 34 runs (32 earned) over 79.1 innings.

Additionally, neither team has a top-10 scoring offense, most notably Cleveland, which ranks 28th in terms of runs per game. Given this, our Baltimore Orioles vs Cleveland Guardians prediction is: Under 9 Total Runs.

Prediction:

 

Under 9 Total Runs

-120
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.