Baltimore Orioles vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Baltimore Orioles
4/16/25 18:35
Cleveland Guardians

Prediction:

 

Cleveland +110

+110
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 by Travis Pulver | in MLB Picks

The Cleveland Indians will try to make it two in a row when they face the Orioles in Game Two of a three-game series today in Baltimore. Fans can follow the action once the game gets underway at Oriole Park at Camden Yards at 6:35 p.m. EST.

After starting the season 2-4, the Indians have stepped up their game, winning seven of their last ten, including a 6-3 win over the Orioles yesterday. Cleveland got 5 2/3 strong innings from starting pitcher Logan Allen (two hits, two walks, six strikeouts. The bullpen gave the Orioles life late in the game, but Emmanuel Case closed the game out in the ninth to secure the victory, 6-3. For the Orioles, it was a fourth consecutive lackluster outing to open the season. Gavin Williams will get the start for Cleveland. He is 1-0 in three starts with a 3.46 ERA and 1.38 WHIP. He has yet to last more than five innings in a game. Dean Kremer gets the start for Baltimore. Kremer is 1-2 with an 8.16 ERA and 1.67 WHIP. He has given up at least one home run in two of his three starts.

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Baltimore Orioles vs Cleveland Guardians Form

Table

Teams Pts P W L
10 Cleveland Guardians
0.543 162 88 74
24 Baltimore Orioles
0.463 162 75 87

Baltimore Orioles and Cleveland Guardians Latest Matches

Baltimore Orioles
Baltimore Orioles Latest matches
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 15, 2025 - MLB

Baltimore Orioles
3 :  6
Cleveland Guardians

Apr 13, 2025 - MLB

Baltimore Orioles
6 :  7
Toronto Blue Jays

Apr 12, 2025 - MLB

Baltimore Orioles
5 :  4
Toronto Blue Jays

Apr 9, 2025 - MLB

Arizona Diamondbacks
9 :  0
Baltimore Orioles

Apr 8, 2025 - MLB

Arizona Diamondbacks
4 :  3
Baltimore Orioles

Apr 7, 2025 - MLB

Arizona Diamondbacks
1 :  5
Baltimore Orioles
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 15, 2025 - MLB

Baltimore Orioles
3 :  6
Cleveland Guardians

Apr 13, 2025 - MLB

Baltimore Orioles
6 :  7
Toronto Blue Jays

Apr 12, 2025 - MLB

Baltimore Orioles
5 :  4
Toronto Blue Jays

Apr 3, 2025 - MLB

Baltimore Orioles
4 :  8
Boston Red Sox

Apr 2, 2025 - MLB

Baltimore Orioles
0 :  3
Boston Red Sox

Mar 31, 2025 - MLB

Baltimore Orioles
8 :  5
Boston Red Sox
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 9, 2025 - MLB

Arizona Diamondbacks
9 :  0
Baltimore Orioles

Apr 8, 2025 - MLB

Arizona Diamondbacks
4 :  3
Baltimore Orioles

Apr 7, 2025 - MLB

Arizona Diamondbacks
1 :  5
Baltimore Orioles

Apr 6, 2025 - MLB

Kansas City Royals
4 :  1
Baltimore Orioles

Apr 5, 2025 - MLB

Kansas City Royals
1 :  8
Baltimore Orioles

Apr 4, 2025 - MLB

Kansas City Royals
8 :  2
Baltimore Orioles
Cleveland Guardians
Cleveland Guardians Latest matches
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 15, 2025 - MLB

Baltimore Orioles
3 :  6
Cleveland Guardians

Apr 13, 2025 - MLB

Cleveland Guardians
2 :  4
Kansas City Royals

Apr 12, 2025 - MLB

Cleveland Guardians
6 :  3
Kansas City Royals

Apr 11, 2025 - MLB

Cleveland Guardians
7 :  0
Kansas City Royals

Apr 10, 2025 - MLB

Cleveland Guardians
6 :  1
Chicago White Sox

Apr 9, 2025 - MLB

Cleveland Guardians
3 :  2
Chicago White Sox
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 13, 2025 - MLB

Cleveland Guardians
2 :  4
Kansas City Royals

Apr 12, 2025 - MLB

Cleveland Guardians
6 :  3
Kansas City Royals

Apr 11, 2025 - MLB

Cleveland Guardians
7 :  0
Kansas City Royals

Apr 10, 2025 - MLB

Cleveland Guardians
6 :  1
Chicago White Sox

Apr 9, 2025 - MLB

Cleveland Guardians
3 :  2
Chicago White Sox

Apr 8, 2025 - MLB

Cleveland Guardians
1 :  0
Chicago White Sox
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 15, 2025 - MLB

Baltimore Orioles
3 :  6
Cleveland Guardians

Apr 6, 2025 - MLB

Los Angeles Angels
6 :  2
Cleveland Guardians

Apr 5, 2025 - MLB

Los Angeles Angels
10 :  4
Cleveland Guardians

Apr 4, 2025 - MLB

Los Angeles Angels
6 :  8
Cleveland Guardians

Apr 2, 2025 - MLB

San Diego Padres
5 :  2
Cleveland Guardians

Apr 1, 2025 - MLB

San Diego Padres
7 :  0
Cleveland Guardians

Baltimore Orioles against Cleveland Guardians : Head to Head (H2H)

Baltimore Orioles

50 %

Cleveland Guardians

50 %

Apr 15, 2025 - MLB

Baltimore Orioles
3 :  6
Cleveland Guardians

Aug 4, 2024 - MLB

Cleveland Guardians
5 :  9
Baltimore Orioles

Aug 3, 2024 - MLB

Cleveland Guardians
4 :  7
Baltimore Orioles

Aug 1, 2024 - MLB

Cleveland Guardians
10 :  3
Baltimore Orioles

Jun 26, 2024 - MLB

Baltimore Orioles
4 :  2
Cleveland Guardians

Jun 25, 2024 - MLB

Baltimore Orioles
8 :  10
Cleveland Guardians

Baltimore Orioles - Cleveland Guardians Key Points

  1. Cleveland leads the all-time series vs. Baltimore 1162-882-19.
  2. Baltimore last won a season series vs. Cleveland in 2016 (5-1).
  3. 44% of moneyline tickets are on Cleveland and 56% on Baltimore, but 89% of the moneyline handle is on the Orioles.
  4. 95% of tickets and handle is on the OVER.
Up to $250 to bet on Baltimore Orioles - Cleveland Guardians! 

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Our Baltimore Orioles vs Cleveland Guardians Prediction

I’m a little surprised that the Indians have plus money odds for this game. Not only are they coming off a win over the Orioles, but they have played better baseball all season long. Factor in Williams pitching well up to this point and how poorly Kremer has, and it is hard to justify betting on Baltimore.

Our Indians vs. Orioles Pick: Cleveland ML

Prediction:

 

Cleveland +110

+110
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Baltimore Orioles vs Cleveland Guardians Picks