Arizona Diamondbacks vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Arizona Diamondbacks
8/20/25 15:40
Cleveland Guardians

Prediction:

 

Under 9 runs.

-110
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 by Stephen Abiola | in MLB Picks

Arizona Diamondbacks (61-66) will look to continue their improvement this month when they take on Cleveland Guardians (64-61) on Wednesday evening. The Diamondbacks, who have averaged 5.4 runs per contest in August, will want to wrap up this three-game series with a win after recovering from a 3-1 loss in the first game to defeat the Guardians 6-5 on Tuesday night. The D-Backs are 5-5 in their previous 10 assignments, sitting fourth in the NL West.

The Guardians, meanwhile, are in dire need of a series win after being swept aside 3-0 by Atlanta in their previous assignment. Their 64-61 record is good for third in the AL Central division, and they are just 0.5 games behind the Royals in second place. However, the Royals are currently playing beautiful baseball, and the Guardians must improve quickly to pip them to the coveted second spot. They don’t have any new injuries ahead of the clash against the D-Backs.

Arizona Diamondbacks vs Cleveland Guardians Form

Table

Teams Pts P W L
10 Cleveland Guardians
0.543 162 88 74
18 Arizona Diamondbacks
0.494 162 80 82

Arizona Diamondbacks and Cleveland Guardians Latest Matches

Arizona Diamondbacks
Arizona Diamondbacks Latest matches
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 18, 2025 - MLB

Arizona Diamondbacks
1 :  3
Cleveland Guardians

Aug 17, 2025 - MLB

Colorado Rockies
6 :  5
Arizona Diamondbacks

Aug 16, 2025 - MLB

Colorado Rockies
10 :  7
Arizona Diamondbacks

Aug 15, 2025 - MLB

Colorado Rockies
4 :  3
Arizona Diamondbacks

Aug 14, 2025 - MLB

Colorado Rockies
2 :  8
Arizona Diamondbacks

Aug 13, 2025 - MLB

Texas Rangers
4 :  6
Arizona Diamondbacks
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 18, 2025 - MLB

Arizona Diamondbacks
1 :  3
Cleveland Guardians

Aug 10, 2025 - MLB

Arizona Diamondbacks
13 :  6
Colorado Rockies

Aug 9, 2025 - MLB

Arizona Diamondbacks
6 :  5
Colorado Rockies

Aug 8, 2025 - MLB

Arizona Diamondbacks
6 :  1
Colorado Rockies

Aug 6, 2025 - MLB

Arizona Diamondbacks
2 :  3
San Diego Padres

Aug 5, 2025 - MLB

Arizona Diamondbacks
5 :  10
San Diego Padres
W W W L L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 17, 2025 - MLB

Colorado Rockies
6 :  5
Arizona Diamondbacks

Aug 16, 2025 - MLB

Colorado Rockies
10 :  7
Arizona Diamondbacks

Aug 15, 2025 - MLB

Colorado Rockies
4 :  3
Arizona Diamondbacks

Aug 14, 2025 - MLB

Colorado Rockies
2 :  8
Arizona Diamondbacks

Aug 13, 2025 - MLB

Texas Rangers
4 :  6
Arizona Diamondbacks

Aug 12, 2025 - MLB

Texas Rangers
2 :  3
Arizona Diamondbacks
Cleveland Guardians
Cleveland Guardians Latest matches
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 18, 2025 - MLB

Arizona Diamondbacks
1 :  3
Cleveland Guardians

Aug 17, 2025 - MLB

Cleveland Guardians
4 :  5
Atlanta Braves

Aug 16, 2025 - MLB

Cleveland Guardians
1 :  10
Atlanta Braves

Aug 15, 2025 - MLB

Cleveland Guardians
0 :  2
Atlanta Braves

Aug 14, 2025 - MLB

Cleveland Guardians
9 :  4
Miami Marlins

Aug 13, 2025 - MLB

Cleveland Guardians
4 :  13
Miami Marlins
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 17, 2025 - MLB

Cleveland Guardians
4 :  5
Atlanta Braves

Aug 16, 2025 - MLB

Cleveland Guardians
1 :  10
Atlanta Braves

Aug 15, 2025 - MLB

Cleveland Guardians
0 :  2
Atlanta Braves

Aug 14, 2025 - MLB

Cleveland Guardians
9 :  4
Miami Marlins

Aug 13, 2025 - MLB

Cleveland Guardians
4 :  13
Miami Marlins

Aug 12, 2025 - MLB

Cleveland Guardians
4 :  3
Miami Marlins
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Aug 18, 2025 - MLB

Arizona Diamondbacks
1 :  3
Cleveland Guardians

Aug 10, 2025 - MLB

Chicago White Sox
6 :  4
Cleveland Guardians

Aug 9, 2025 - MLB

Chicago White Sox
1 :  3
Cleveland Guardians

Aug 8, 2025 - MLB

Chicago White Sox
5 :  9
Cleveland Guardians

Aug 6, 2025 - MLB

New York Mets
1 :  4
Cleveland Guardians

Aug 5, 2025 - MLB

New York Mets
2 :  3
Cleveland Guardians

Arizona Diamondbacks against Cleveland Guardians : Head to Head (H2H)

Arizona Diamondbacks

75 %

Cleveland Guardians

25 %

Aug 18, 2025 - MLB

Arizona Diamondbacks
1 :  3
Cleveland Guardians

Aug 7, 2024 - MLB

Cleveland Guardians
3 :  5
Arizona Diamondbacks

Aug 7, 2024 - MLB

Cleveland Guardians
3 :  7
Arizona Diamondbacks

Aug 5, 2024 - MLB

Cleveland Guardians
6 :  7
Arizona Diamondbacks

Arizona Diamondbacks - Cleveland Guardians Key Points

  1. The Guardians are 4-11 in their last 15 matches against Arizona.
  2. The total runs went under in three of the last four Arizona vs Cleveland clashes.
  3. The total runs went under in four of the last six Arizona matches.
  4. The total went under in six of the last 10 Arizona matches at home.

Our Arizona Diamondbacks vs Cleveland Guardians Prediction

Bookmakers anticipate a close game with the Diamondbacks being the slight -136 betting favorites. On paper, the Guardians are the in-form side, winning 12 of their last 18 matches all-time. They also boast an impressive record of 6-2 in their previous eight games on the road. However, their recent record has been wanting, scoring an average of 2.6 runs per game in the last five matches. While at it, their pitchers allowed an average of 5.6 runs per contest. This could be their weakest link against the Diamondbacks, who have an average of 4.4 runs in the last five fixtures. We wouldn’t want to bet on Cleveland to cover the +1 run line here.

Our prediction for Arizona Diamondbacks vs Cleveland Guardians: Under 9 runs.

Prediction:

 

Under 9 runs.

-110
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Arizona Diamondbacks vs Cleveland Guardians Picks