Detroit Pistons vs Cleveland Cavaliers Prediction & Picks - NBA
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by Lou Aguila | in NBA Picks
The Detroit Pistons and the Cleveland Cavaliers square off for the third time this season.
The Pistons, playing at home, face a golden opportunity to cover a manageable spread here at -6.5 points against the Cavs, who could play again without their All-Star backcourt.
Hot Pick: The Pistons -6.5 points
Potential Payout: $210 on a $110 Bet (-110 on Caesars Sportsbook)
Current Form:
The Detroit Pistons defeated the depleted Oklahoma City Thunder, 124-116, two days after falling to another Western Conference powerhouse, the San Antonio Spurs, 103-114, on February 23. The Pistons are head and shoulders above the rest of the Eastern Conference with a 43-14 record, 5.5 games above the closest trailers, the 38-20 Boston Celtics.
The Cavaliers suffered their second loss in three games following a 116-118 setback against the Giannis-less Milwaukee Bucks. James Harden, Donovan Mitchell, and Evan Mobley sat out in this game due to injuries, putting the scoring load on the shoulders of Jarrett Allen, who recorded 27 points and 11 boards in 32 minutes of play. The 37-23 Cavs are trailing the Pistons by 7.5 games in the Central Division standings.
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Detroit Pistons vs Cleveland Cavaliers Form
Table
| Teams | % | P | W | L | Series |
|---|---|---|---|---|---|
|
3
|
0.732 | 82 | 60 | 22 | 3 |
|
8
|
0.634 | 82 | 52 | 30 | 1 |
Detroit Pistons and Cleveland Cavaliers Latest Matches
5/6 (83%)
1/6 (17%)
Feb 27, 2026 - NBA
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4/6 (67%)
2/6 (33%)
Feb 27, 2026 - NBA
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Feb 3, 2026 - NBA
5/6 (83%)
1/6 (17%)
Feb 21, 2026 - NBA
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3/6 (50%)
3/6 (50%)
Feb 27, 2026 - NBA
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6/6 (100%)
0/6 (0%)
Feb 24, 2026 - NBA
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Jan 23, 2026 - NBA
3/6 (50%)
3/6 (50%)
Feb 27, 2026 - NBA
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Detroit Pistons against Cleveland Cavaliers : Head to Head (H2H)
50 %
50 %
Feb 27, 2026 - NBA
Jan 4, 2026 - NBA
Oct 27, 2025 - NBA
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Players list
C. Cunningham
T. Harris
D. Robinson
D. Schroder
S. Merrill
E. Mobley
J. Tyson
Substitutes
D. Jenkins
M. Sasser
C. LeVert
P. Reed
R. Holland
K. Ellis
C. Porter
T. Proctor
D. Brown II
N. Tomlin
T. Enaruna
Detroit Pistons - Cleveland Cavaliers Key Points
- Detroit is 5-0 ATS in its last 5 games against an opponent in the Eastern Conference
- Detroit is 5-2 ATS in its last 7 games.
- Cleveland is 0-5 ATS in its last 5 games against an opponent in the Central Division
- Cleveland is 13-2 SU in its last 15 games against Detroit.
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Our Detroit Pistons vs Cleveland Cavaliers Prediction
Fearless Forecast: The Pistons topple the Cavs 116-106
The Pistons face a manageable -6.5-point handicap against the Cavs, who have their All-Star backcourt listed with injuries. Mitchell (groin) has already been ruled out for this game vs. the Pistons, while Harden (thumb) is a game-time decision.
The Pistons should take care of their business with these Cavaliers, who could be without their backcourt duo (if Harden sits out again). Detroit has been poor against the spread in last 5 home games, but this is a team that plays out its best basketball when matched up against East contenders. The Pistons are 5-0 ATS in their last 5 games against East teams.
Our betting prediction for the Cleveland Cavaliers vs. the Detroit Pistons: The Pistons -6.5 pointsAll tips are fully researched and given in good faith, but profits cannot be guaranteed.
