USA - NFL
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Travis Pulver | in NFL Picks
The Lions will go for their third win of the young season Sunday, September 28, when they host the Cleveland Browns at Ford Field in Detroit, MI. Kickoff for this interconference matchup is scheduled for 1 p.m. EST, and the game will be broadcast on Fox.
Any concerns that arose after their Week 1 loss have disappeared with how the Lions have bounced back since then. They demolished the Chicago Bears, 52-21, beating them in just about every facet of the game. Last week, they went into Baltimore as 4.5-point underdogs and shut down the Ravens' run game while running for 224 yards and four touchdowns. Of course, it will not be easy to run the ball on the Browns' defensive front, led by Myles Garrett. Through Week 3, the Browns rank No. 1 in total defense (204.3 yards per game allowed) and first against the run (57.3 yards per game allowed). However, the Lions do have a top-ten offensive line, according to PFF. But even if the Browns' defense can step up to the plate, they can’t expect to get much help from the offensive side of the ball. With Joe Flacco at quarterback, the Browns offense is averaging 15.3 points per game (No. 30).
Limited Offer. Currently at Fanatics
Cleveland Browns vs Detroit Lions Form
Table
| Teams | % | P | W | D | L |
|---|---|---|---|---|---|
|
12
|
0.667 | 6 | 4 | 0 | 2 |
|
27
|
0.167 | 6 | 1 | 0 | 5 |
Cleveland Browns and Detroit Lions Latest Matches
1/6 (17%)
0/6 (0%)
5/6 (83%)
Sep 21, 2025 - NFL
Sep 14, 2025 - NFL
Sep 7, 2025 - NFL
Jan 4, 2025 - NFL
Dec 29, 2024 - NFL
Dec 22, 2024 - NFL
2/6 (33%)
0/6 (0%)
4/6 (67%)
Sep 21, 2025 - NFL
Sep 7, 2025 - NFL
Dec 29, 2024 - NFL
Dec 15, 2024 - NFL
Nov 21, 2024 - NFL
Nov 3, 2024 - NFL
0/6 (0%)
0/6 (0%)
6/6 (100%)
Sep 14, 2025 - NFL
Jan 4, 2025 - NFL
Dec 22, 2024 - NFL
Dec 8, 2024 - NFL
Dec 2, 2024 - NFL
Nov 17, 2024 - NFL
4/6 (67%)
0/6 (0%)
2/6 (33%)
Sep 22, 2025 - NFL
Sep 14, 2025 - NFL
Sep 7, 2025 - NFL
Jan 18, 2025 - NFL
Jan 5, 2025 - NFL
Dec 30, 2024 - NFL
4/6 (67%)
0/6 (0%)
2/6 (33%)
Sep 14, 2025 - NFL
Jan 18, 2025 - NFL
Jan 5, 2025 - NFL
Dec 15, 2024 - NFL
Dec 5, 2024 - NFL
Nov 28, 2024 - NFL
5/6 (83%)
0/6 (0%)
1/6 (17%)
Sep 22, 2025 - NFL
Sep 7, 2025 - NFL
Dec 30, 2024 - NFL
Dec 22, 2024 - NFL
Nov 24, 2024 - NFL
Nov 10, 2024 - NFL
Cleveland Browns - Detroit Lions Key Points
- The Lions lead the all-time series vs. the Browns 19-6.
- Detroit and Cleveland last played during the 2021 season (November 21, 2021), a game the Browns won 13-10.
- Betting Public: 70% of spread tickets are on the Browns (+10), but only 45% of the handle.
- Betting Pubic: 60% of TOTAL tickets and 68% of the handle are on the UNDER.
Limited Offer. Currently at Fanatics
Our Cleveland Browns vs Detroit Lions Prediction
You almost have to feel a little sorry for the Browns defense. With a unit playing as well as they are, they should be undefeated and making the postseason. But with one of the worst offenses in the league…The question here is not whether the Lions will win this game, because they should, but whether they’ll cover. With 70% of tickets on the Browns' spread, it appears that the public is backing the Browns. While they have played well, this game will be similar to the Baltimore game in Week 2; the game was close at halftime with the Ravens up 10-3. But then Baltimore turned it on in the second half, scoring 31 points.
Our Browns vs. Lions Pick: Lions -9.5
Grab some extra cash for your Cleveland Browns vs Detroit Lions bet!
Looking to bet on Cleveland Browns vs Detroit Lions? Stop everything, Fanatics has a deal for you! For this NFL match, Fanatics is offering an exclusive bonus of up to $250. This is one of the top deals of the moment and surely won't last so take advantage today!
Registration takes a quick 3 minutes and you'll be on your way to extra cash for your bet on Cleveland Browns vs Detroit Lions!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
Limited Offer. Currently at Fanatics
