San Francisco Giants vs Cincinnati Reds Prediction & Picks - MLB
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by Travis Pulver | in MLB Picks
The San Francisco Giants (54-78, 31-33 Home) will go for the series sweep today when they host the Cincinnati Reds (62-71, 30-35 Away) at Oracle Park. Game time is scheduled for 3:45 p.m. EST on MLB.TV.
It was all San Francisco in the opener Monday as the Giants shut the Reds out, 5-0. Yesterday’s game was a little more competitive, but the outcome was the same as the Giants won 3-1.
Landon Roupp is scheduled to get the start for the Giants today. Roupp is 7-13 in 25 starts this season with a 4.34 ERA, a 1.31 WHIP, and teams have been hitting .226 against him. Through 11 starts at home, he is 3-7 with a 4.22 ERA and a .200 OBA. His last home win was on July 6 against Toronto. He recorded a loss in his last five starts.
As for the Reds, Cincinnati will start Nick Lodolo. He has gone 3-3 in 15 starts this season with a 5.04 ERA, 1.52 WHIP, and teams have hit .288 against him. In six starts on the road, he is 1-1 with a 5.59 ERA and an OBA of .310. His last road win was on May 25 vs. the Mets in Queens.
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San Francisco Giants vs Cincinnati Reds Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
24
|
0.463 | 162 | 75 | 87 |
|
27
|
0.401 | 162 | 65 | 97 |
San Francisco Giants and Cincinnati Reds Latest Matches
2/6 (33%)
4/6 (67%)
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3/6 (50%)
3/6 (50%)
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1/6 (17%)
5/6 (83%)
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2/6 (33%)
4/6 (67%)
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2/6 (33%)
4/6 (67%)
Aug 20, 2026 - MLB
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2/6 (33%)
4/6 (67%)
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San Francisco Giants against Cincinnati Reds : Head to Head (H2H)
33 %
67 %
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Mar 13, 2026 - MLB Spring Training
Mar 13, 2026 - MLB Spring Training
San Francisco Giants - Cincinnati Reds Key Points
- The Giants and Reds have played 17 times over the last three seasons; San Francisco went 10-7 in those games.
- San Francisco is 34-30 ATS (run line) at home this season; Cincinnati is 35-30 ATS (run line) on the road.
- The OVER is 28-32-4 for the Giants at home and 34-30-1 for the Reds on the road.
- Betting Public: 33% of total tickets and 31% of the handle are on the UNDER.
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Our San Francisco Giants vs Cincinnati Reds Prediction
This game will go one of three ways: (1) someone’s lineup is going to wake up against the other’s hittable pitcher and that team will win the game and probably cover the run line, (2) both lineups will take advantage of weak pitching and they’ll combine for enough runs to go OVER the total, or (3) despite lackluster pitching, both lineups will continue to struggle at the plate, resulting in a low scoring game (so bet the UNDER). I’m less impressed with the lineups than the pitchers, so I’m taking the UNDER.
Our Cincinnati vs. San Francisco Pick: UNDER 8
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.