San Francisco Giants vs Cincinnati Reds Prediction & Picks - MLB

USA - MLB

San Francisco Giants
4/7/25 21:45
Cincinnati Reds

Prediction:

 

UNDER 7

-122
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 by Travis Pulver | in MLB Picks

The Cincinnati Reds will try to get things turned around as they head to San Francisco for a three-game series vs. the Giants. Game One is scheduled to get underway tonight at 9:45 p.m. EST.

It has certainly been a struggle for the Reds so far this season. They have managed to win one in each series (they’ve played three), and that’s it. After making history with three consecutive 1-0 losses, they lost a fourth straight game but scored two runs (3-2). Their bats finally woke up against the Brewers on Saturday for 14 hits and 11 runs, but then it came crashing back down to Earth in the series finale Sunday in an 8-2 loss. San Francisco’s only loss of the season came in their season-opening series vs. the Reds in Cincinnati (Game Two, 3-2). They have since gone 7-0 and sit in first place in the NL West, a game above the LA Dodgers.

The Reds will give the ball to Hunter Greene tonight. He started the season opener against the Giants, lasting five innings and giving up three hits, including a home run, and two runs while striking out eight. Greene was also the pitcher for one of the 1-0 losses (vs. Texas, seven innings, three hits, one run, eight strikeouts). San Francisco is going with Logan Webb, who started the season opener vs. Greene but didn’t factor into the decision.

San Francisco Giants vs Cincinnati Reds Form

Table

Teams Pts P W L
13 Cincinnati Reds
0.512 162 83 79
16 San Francisco Giants
0.5 162 81 81

San Francisco Giants and Cincinnati Reds Latest Matches

San Francisco Giants
San Francisco Giants Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Apr 6, 2025 - MLB

San Francisco Giants
5 :  4
Seattle Mariners

Apr 5, 2025 - MLB

San Francisco Giants
4 :  1
Seattle Mariners

Apr 2, 2025 - MLB

Houston Astros
3 :  6
San Francisco Giants

Apr 1, 2025 - MLB

Houston Astros
1 :  3
San Francisco Giants

Mar 31, 2025 - MLB

Houston Astros
2 :  7
San Francisco Giants

Mar 30, 2025 - MLB

Cincinnati Reds
3 :  6
San Francisco Giants
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 6, 2025 - MLB

San Francisco Giants
5 :  4
Seattle Mariners

Apr 5, 2025 - MLB

San Francisco Giants
4 :  1
Seattle Mariners

Sep 15, 2024 - MLB

San Francisco Giants
3 :  4
San Diego Padres

Sep 5, 2024 - MLB

San Francisco Giants
3 :  2
Arizona Diamondbacks

Sep 3, 2024 - MLB

San Francisco Giants
7 :  8
Arizona Diamondbacks

Aug 31, 2024 - MLB

San Francisco Giants
3 :  4
Miami Marlins
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 2, 2025 - MLB

Houston Astros
3 :  6
San Francisco Giants

Apr 1, 2025 - MLB

Houston Astros
1 :  3
San Francisco Giants

Mar 31, 2025 - MLB

Houston Astros
2 :  7
San Francisco Giants

Mar 30, 2025 - MLB

Cincinnati Reds
3 :  6
San Francisco Giants

Mar 29, 2025 - MLB

Cincinnati Reds
3 :  2
San Francisco Giants

Mar 27, 2025 - MLB

Cincinnati Reds
4 :  6
San Francisco Giants
Cincinnati Reds
Cincinnati Reds Latest matches
W L L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 5, 2025 - MLB

Milwaukee Brewers
7 :  11
Cincinnati Reds

Apr 4, 2025 - MLB

Milwaukee Brewers
3 :  2
Cincinnati Reds

Apr 3, 2025 - MLB

Milwaukee Brewers
1 :  0
Cincinnati Reds

Apr 2, 2025 - MLB

Cincinnati Reds
0 :  1
Texas Rangers

Apr 1, 2025 - MLB

Cincinnati Reds
0 :  1
Texas Rangers

Mar 31, 2025 - MLB

Cincinnati Reds
14 :  3
Texas Rangers
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 2, 2025 - MLB

Cincinnati Reds
0 :  1
Texas Rangers

Apr 1, 2025 - MLB

Cincinnati Reds
0 :  1
Texas Rangers

Mar 31, 2025 - MLB

Cincinnati Reds
14 :  3
Texas Rangers

Mar 30, 2025 - MLB

Cincinnati Reds
3 :  6
San Francisco Giants

Mar 29, 2025 - MLB

Cincinnati Reds
3 :  2
San Francisco Giants

Mar 27, 2025 - MLB

Cincinnati Reds
4 :  6
San Francisco Giants
W L L L W
Victories

2/5 (40%)

Defeats

3/5 (60%)

Apr 5, 2025 - MLB

Milwaukee Brewers
7 :  11
Cincinnati Reds

Apr 4, 2025 - MLB

Milwaukee Brewers
3 :  2
Cincinnati Reds

Apr 3, 2025 - MLB

Milwaukee Brewers
1 :  0
Cincinnati Reds

Sep 15, 2024 - MLB

Minnesota Twins
9 :  2
Cincinnati Reds

Sep 9, 2024 - MLB

Atlanta Braves
0 :  1
Cincinnati Reds

San Francisco Giants against Cincinnati Reds : Head to Head (H2H)

San Francisco Giants

67 %

Cincinnati Reds

33 %

Mar 30, 2025 - MLB

Cincinnati Reds
3 :  6
San Francisco Giants

Mar 29, 2025 - MLB

Cincinnati Reds
3 :  2
San Francisco Giants

Mar 27, 2025 - MLB

Cincinnati Reds
4 :  6
San Francisco Giants

Aug 4, 2024 - MLB

Cincinnati Reds
2 :  8
San Francisco Giants

Aug 3, 2024 - MLB

Cincinnati Reds
6 :  4
San Francisco Giants

Aug 2, 2024 - MLB

Cincinnati Reds
0 :  3
San Francisco Giants

San Francisco Giants - Cincinnati Reds Key Points

  1. The Giants are off to an 8-1, 3-0 at home start while the Reds are 3-7, 1-3 away.
  2. San Francisco leads the all-time series vs. Cincinnati 1239-1036-15.
  3. Cincinnati went 1-2 at home and on the road vs. San Francisco last season.
  4. 95% of the moneyline tickets and 99% of the handle is on San Francisco.

Our San Francisco Giants vs Cincinnati Reds Prediction

When these two pitched in the opener, the teams scored ten runs. But since then, the Reds' lineup has struggled to make contact. San Francisco has been hitting well this season, but Greene did a great job against them in the opener. I’m betting the Reds' bats will go silent again, but Greene will keep the Giants in check. The easy bet here is the Giants ML, but I’m going with something else.

Our Reds vs. Giants Pick: UNDER 7

Prediction:

 

UNDER 7

-122
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

San Francisco Giants vs Cincinnati Reds Picks