Minnesota Twins vs Cincinnati Reds Prediction & Picks - MLB
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by Matt Lowrimore | in MLB Picks
A full 15-game slate is scheduled in the MLB on Friday, and will include an interleague matchup between the Minnesota Twins and the Cincinnati Reds. Let’s take a look at the match statistics and predictions for this game between the Twins and the Reds.
Cincinnati is coming off a loss on Thursday, but still won the three-game series against the San Francisco Giants. The Reds are now set to start Brandon Williamson in Game 1 of this series against the Twins. Williamson is 1-1 on the season and has an ERA of 5.28. Through three starts, he has allowed nine earned runs over 15.1 innings.
Coming off an off-day on Thursday, Minnesota is set to counter with Joe Ryan in Game 1 of this series. He enters this game with a record of 2-1 on the season and has an ERA of 3.80. Through his four starts, he has allowed nine earned runs over 21.1 innings.
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Minnesota Twins vs Cincinnati Reds Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
15
|
0.508 | 61 | 31 | 30 |
|
22
|
0.453 | 64 | 29 | 35 |
Minnesota Twins and Cincinnati Reds Latest Matches
4/6 (67%)
2/6 (33%)
Apr 15, 2026 - MLB
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5/6 (83%)
1/6 (17%)
Apr 15, 2026 - MLB
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Apr 9, 2026 - MLB
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3/6 (50%)
3/6 (50%)
Apr 12, 2026 - MLB
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Apr 1, 2026 - MLB
Mar 30, 2026 - MLB
3/6 (50%)
3/6 (50%)
Apr 16, 2026 - MLB
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Apr 10, 2026 - MLB
3/6 (50%)
3/6 (50%)
Apr 16, 2026 - MLB
Apr 15, 2026 - MLB
Apr 14, 2026 - MLB
Apr 12, 2026 - MLB
Apr 11, 2026 - MLB
Apr 10, 2026 - MLB
4/6 (67%)
2/6 (33%)
Apr 9, 2026 - MLB
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Apr 7, 2026 - MLB
Apr 6, 2026 - MLB
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Apr 4, 2026 - MLB
Minnesota Twins against Cincinnati Reds : Head to Head (H2H)
67 %
33 %
Jun 19, 2025 - MLB
Jun 18, 2025 - MLB
Jun 17, 2025 - MLB
Sep 15, 2024 - MLB
Sep 20, 2023 - MLB
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Minnesota Twins - Cincinnati Reds Key Points
- Brandon Williamson has an ERA of 5.28
- Cincinnati is averaging 3.37 runs per game
- Joe Ryan has an ERA of 3.80
- Minnesota is averaging 5.42 runs per game
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Our Minnesota Twins vs Cincinnati Reds Prediction
Minnesota is the heavy favorite in this game; however, Cincinnati looks to be the best betting option. The Twins’ starter, Ryan, has only been decent this season, as shown by his average ERA. In terms of his splits, he has made just one start at home this season, where he allowed three runs (two earned) over 5.0 innings.
Despite Ryan only being decent, Minnesota has easily been one of the top offenses in the league. They are averaging 5.4 runs per game, the fourth-best mark in the MLB. Because the Twins have a huge advantage in terms of their scoring offense, our Minnesota Twins vs Cincinnati Reds prediction is: Minnesota Twins ML.All tips are fully researched and given in good faith, but profits cannot be guaranteed.