Miami Marlins vs Cincinnati Reds Prediction & Picks - MLB

Prediction published on 4/21/25, 3:27 PM  by Carlos Zabala | Modified on 2/11/26 at 8:38 AM in MLB Picks

The Reds scored the most runs of any team this season, beating the Orioles 24-2, winning the series 2-1. They now head to Miami for another series against the Marlins after playing a four-game series in 2024 at LoanDepot Park, which the Reds defeated 3-1.

Although unconfirmed, Lodolo is expected to return from the paternity list in time to start Game 1 against the Marlins. Meanwhile, the Marlins' starting pitcher is Max Meyer, who, despite allowing two home runs to the D-backs in his last outing, has pitched three complete games in his last outings.

For the Reds, Sunday afternoon against the Orioles was a historic game, as they tied the record of 24 runs they set against the Rockies in 1999. With 25 hits, no Reds player was left out of the offensive feast. By the third inning, the Game Total Over odds of 8.5 were already being collected when the Reds scored seven runs in the third inning. Noveli Marte and Winns, batting as the bottom two in the order, were the ones who took the most advantage of the offensive feast. Marte went 5-for-7 with 5 RBIs, and Wynns went 6-for-7 with 6 RBIs in a historic game for them.