Cleveland Guardians vs Cincinnati Reds Prediction & Picks - MLB
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by Stephen Abiola | in MLB Picks
Cleveland Guardians (24-22) and Cincinnati Reds (24-21) will clash in the second game of this series at Progressive Field on Saturday evening. The Guardians opened this three-game home series with a surprising 6-7 defeat on Friday night. Cleveland tried to rally late in the game, but the visitors hung on for a win in the Ohio Cup opener. The Guardians will now be keen to even out this series and improve their abysmal record against the Reds.
Cincinnati Reds, meanwhile, have looked comfortable playing on the road this season, which was evident on Friday night. They got another impressive start from Andrew Abbott while Matt McLain hit a homer to help them get a fully deserved 6-1 lead. However, things went a bit sideways when Ashcraft took the mound in the eighth, allowing the Reds back into the game. It wasn’t an entirely convincing performance from the Reds.
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Cleveland Guardians vs Cincinnati Reds Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
19
|
0.487 | 119 | 58 | 61 |
|
21
|
0.479 | 117 | 56 | 61 |
Cleveland Guardians and Cincinnati Reds Latest Matches
3/6 (50%)
3/6 (50%)
May 15, 2026 - MLB
May 13, 2026 - MLB
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May 9, 2026 - MLB
3/6 (50%)
3/6 (50%)
May 15, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
May 11, 2026 - MLB
May 10, 2026 - MLB
May 9, 2026 - MLB
3/6 (50%)
3/6 (50%)
May 7, 2026 - MLB
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May 2, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 15, 2026 - MLB
May 14, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
May 10, 2026 - MLB
May 9, 2026 - MLB
3/6 (50%)
3/6 (50%)
May 14, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
May 10, 2026 - MLB
May 9, 2026 - MLB
May 8, 2026 - MLB
1/6 (17%)
5/6 (83%)
May 15, 2026 - MLB
May 7, 2026 - MLB
May 6, 2026 - MLB
May 5, 2026 - MLB
May 4, 2026 - MLB
May 3, 2026 - MLB
Cleveland Guardians against Cincinnati Reds : Head to Head (H2H)
83 %
17 %
May 15, 2026 - MLB
Mar 22, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Feb 21, 2026 - MLB Spring Training
Jun 11, 2024 - MLB
Sep 27, 2023 - MLB
Cleveland Guardians - Cincinnati Reds Key Points
- The total runs went over in the last four Cincinnati Reds matches.
- The total runs went over 7.5 in four of the last five Cleveland Guardians vs Cincinnati Reds clashes.
- The total runs went over 7.5 in five of the last eight Cleveland Guardians matches.
- The total runs went over 7.5 in the last four Cincinnati Reds matches
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Our Cleveland Guardians vs Cincinnati Reds Prediction
Cleveland is the -180 betting favorite, presenting an exciting value. However, we cannot trust them on the moneyline due to their uninspiring head-to-head record. The Guardians lost six of their last seven games against the Reds. Last season, the Reds dominated this fixture, winning five of six. However, they’ll look to make amends today by sending Joey Castillo into the bump. The left-handed pitcher has a solid 3-1 record this season with a 2.98 ERA. He clearly outperforms Chris Paddack, who has a 0-5 record with a high 7.63 ERA. Overall, we see the Guardians running riot in Game 2 with Paddack on the mound.
Our prediction for Cleveland Guardians vs Cincinnati Reds: Over 7.5 runs.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.