St. Louis Cardinals vs Chicago White Sox Prediction & Picks - MLB
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by Bill Christy | in MLB Picks
The rubber match between the St. Louis Cardinals and the Chicago White Sox will take place this afternoon in St. Louis.
The Cardinals were powered by Alec Burleson and Joshua Baez in game one. They combined to go 5-8 with 3 doubles and 4 RBIs in the 7-3 win. Matthew Liberatore started but only went 4.1 innings and did not factor into the decision. The bullpen came in and pitched the other 5 innings and allowed just 1 run on 3 hits.
Game two was a much tighter contested game. The White Sox came into the 9th inning trailing 5-4. Down to their last out, Randal Grichuk launched a 2-run home run to deep right field and gave the White Sox a 6-5 lead. Bryan Hudson closed the game out for Chicago and picked up his 8th save of the season.
In both games, the teams have combined for double-digit runs. The over has hit in each, and now today, they will have the opportunity to do the same thing again. Sean Burke and Michael McGreevy will start for their respective teams today. Both men have ERAs over 3.50 for the season and will likely have trouble keeping these hot lineups under wraps today.
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St. Louis Cardinals vs Chicago White Sox Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
12
|
0.519 | 162 | 84 | 78 |
|
19
|
0.475 | 162 | 77 | 85 |
St. Louis Cardinals and Chicago White Sox Latest Matches
2/6 (33%)
4/6 (67%)
Sep 12, 2026 - MLB
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3/6 (50%)
3/6 (50%)
Sep 12, 2026 - MLB
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2/6 (33%)
4/6 (67%)
Sep 9, 2026 - MLB
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2/6 (33%)
4/6 (67%)
Sep 12, 2026 - MLB
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Sep 6, 2026 - MLB
2/6 (33%)
4/6 (67%)
Sep 10, 2026 - MLB
Sep 9, 2026 - MLB
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2/6 (33%)
4/6 (67%)
Sep 12, 2026 - MLB
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St. Louis Cardinals against Chicago White Sox : Head to Head (H2H)
60 %
40 %
Sep 12, 2026 - MLB
Sep 11, 2026 - MLB
Jun 19, 2025 - MLB
May 5, 2024 - MLB
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St. Louis Cardinals - Chicago White Sox Key Points
- Over is 5-0-1 in McGreevys last 6 starts as an underdog.
- Over is 7-0 in McGreevys last 7 starts with 5 days of rest.
- Over is 4-0-1 in the last 5 meetings.
- Over is 5-2 in the last 7 White Sox games.
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Our St. Louis Cardinals vs Chicago White Sox Prediction
McGreevy has given up 16 runs in his last 22 innings of work and walked 2 batters in each of his last 4 starts. He will face Sean Burke of the White Sox, who is coming off a start in which he allowed 7 runs on 8 hits in just 1.1 innings against the Pirates. We expect both starters' struggles to continue here and the over to hit for the 3rd straight game in this series.
Our prediction for St. Louis Cardinals vs Chicago White Sox: Over 8.5
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