Chicago White Sox vs Seattle Mariners Prediction & Picks - MLB

USA - MLB

Chicago White Sox
8/6/25 21:40
Seattle Mariners

Prediction:

 

Mariners -1.5.

-119
$150 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Carlos Zabala in MLB Picks

In May of this year, Seattle won the White Sox-Mariners series 2-1, and in the new series at T-Mobile Field, the Mariners took an 8-3 lead on Tuesday. The Mariners achieved this thanks to a strong offensive outing by Julio Rodríguez, who went 2-for-5, Naylor, who went 2-for-3, and Polanco, who went 2-for-4, but no hit generated more excitement than the two-run home run by Suárez, the Mariners' newest acquisition, his 37th of the season. In the ninth inning, the White Sox responded late with home runs by Robert and sensational rookie shortstop Montgomery, who hit his eighth home run of the season.

On Wednesday, Kirby will pitch again for the Mariners, and the -255 odds for their win over the White Sox are the lowest for any MLB team that day. Kirby's last start was a solid one in Seattle against the Rangers. He pitched 6.0 innings, allowing just three hits, allowing no runs, and striking out six. The Mariners won 6-0.

Chicago White Sox vs Seattle Mariners Form

Table

Teams % P W L
11
Seattle Mariners
Seattle Mariners
0.539 115 62 53
29
Chicago White Sox
Chicago White Sox
0.368 114 42 72

Chicago White Sox and Seattle Mariners Latest Matches

Chicago White Sox
Chicago White Sox Latest matches
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 5, 2025 - MLB

Chicago White Sox
3 :  8
Seattle Mariners

Aug 3, 2025 - MLB

Chicago White Sox
5 :  8
Los Angeles Angels

Aug 2, 2025 - MLB

Chicago White Sox
1 :  0
Los Angeles Angels

Aug 1, 2025 - MLB

Chicago White Sox
6 :  3
Los Angeles Angels

Jul 30, 2025 - MLB

Philadelphia Phillies
3 :  9
Chicago White Sox

Jul 29, 2025 - MLB

Philadelphia Phillies
6 :  3
Chicago White Sox
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 30, 2025 - MLB

Philadelphia Phillies
3 :  9
Chicago White Sox

Jul 29, 2025 - MLB

Philadelphia Phillies
6 :  3
Chicago White Sox

Jul 28, 2025 - MLB

Philadelphia Phillies
2 :  6
Chicago White Sox

Jul 27, 2025 - MLB

Chicago Cubs
5 :  4
Chicago White Sox

Jul 26, 2025 - MLB

Chicago Cubs
6 :  1
Chicago White Sox

Jul 25, 2025 - MLB

Chicago Cubs
5 :  12
Chicago White Sox
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 5, 2025 - MLB

Chicago White Sox
3 :  8
Seattle Mariners

Aug 3, 2025 - MLB

Chicago White Sox
5 :  8
Los Angeles Angels

Aug 2, 2025 - MLB

Chicago White Sox
1 :  0
Los Angeles Angels

Aug 1, 2025 - MLB

Chicago White Sox
6 :  3
Los Angeles Angels

Jul 23, 2025 - MLB

Chicago White Sox
11 :  9
Tampa Bay Rays

Jul 22, 2025 - MLB

Chicago White Sox
3 :  4
Tampa Bay Rays
Seattle Mariners
Seattle Mariners Latest matches
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 5, 2025 - MLB

Chicago White Sox
3 :  8
Seattle Mariners

Aug 3, 2025 - MLB

Texas Rangers
4 :  5
Seattle Mariners

Aug 2, 2025 - MLB

Texas Rangers
6 :  4
Seattle Mariners

Aug 1, 2025 - MLB

Texas Rangers
3 :  4
Seattle Mariners

Jul 31, 2025 - MLB

Texas Rangers
0 :  6
Seattle Mariners

Jul 30, 2025 - MLB

Seattle Mariners
4 :  5
Athletics
W W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 5, 2025 - MLB

Chicago White Sox
3 :  8
Seattle Mariners

Aug 3, 2025 - MLB

Texas Rangers
4 :  5
Seattle Mariners

Aug 2, 2025 - MLB

Texas Rangers
6 :  4
Seattle Mariners

Aug 1, 2025 - MLB

Texas Rangers
3 :  4
Seattle Mariners

Jul 31, 2025 - MLB

Texas Rangers
0 :  6
Seattle Mariners

Jul 23, 2025 - MLB

Milwaukee Brewers
10 :  2
Seattle Mariners
L L W W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 30, 2025 - MLB

Seattle Mariners
4 :  5
Athletics

Jul 29, 2025 - MLB

Seattle Mariners
1 :  6
Athletics

Jul 28, 2025 - MLB

Seattle Mariners
3 :  1
Athletics

Jul 27, 2025 - MLB

Seattle Mariners
1 :  4
Los Angeles Angels

Jul 26, 2025 - MLB

Seattle Mariners
7 :  2
Los Angeles Angels

Jul 25, 2025 - MLB

Seattle Mariners
2 :  3
Los Angeles Angels

Chicago White Sox against Seattle Mariners : Head to Head (H2H)

Chicago White Sox

33 %

Seattle Mariners

67 %

Aug 5, 2025 - MLB

Chicago White Sox
3 :  8
Seattle Mariners

May 21, 2025 - MLB

Seattle Mariners
6 :  5
Chicago White Sox

May 20, 2025 - MLB

Seattle Mariners
0 :  1
Chicago White Sox

May 19, 2025 - MLB

Seattle Mariners
5 :  1
Chicago White Sox

Mar 22, 2025 - MLB Spring Training

Seattle Mariners
14 :  1
Chicago White Sox

Mar 1, 2025 - MLB Spring Training

Chicago White Sox
18 :  9
Seattle Mariners

Chicago White Sox - Seattle Mariners Key Points

  1. The Mariners' 25-22 home record this season and the betting favorite
  2. The White Sox's 17-38 road record and the betting underdog
  3. The White Sox's collective AVG is the second-worst in MLB at 229
  4. The Mariners' O/U record in betting this season is 61-48

Our Chicago White Sox vs Seattle Mariners Prediction

The White Sox's starting pitcher for Wednesday's game is Jonathean Cannon, who has struggled in his last two outings: he allowed 4.1 IP and 5 ER against the Rays on July 23, and in six innings against the Phillies, he allowed 6 ER with just 3 Ks and 2 walks. He also allowed two HRs in each game over his last two starts. Our prediction for White Sox vs Mariners is: Mariners -1.5.

Prediction:

 

Mariners -1.5.

-119
$150 offered for betting!

Grab an extra $150 for your Chicago White Sox vs Seattle Mariners wager!

Bet $5, Get $150

Get ready to experience the thrill of the game with FanDuel's exciting welcome offer, available for use on the Chicago White Sox vs Seattle Mariners matchup!

A minimum bet of $5 will qualify for $150 in bonus bets if your bet wins! This offer is a golden opportunity for new users. Don't miss out on this limited-time deal to enhance your sports betting experience with some extra oomph! Jump into the action today and let FanDuel take your sports engagement to the next level!

$150 available for Chicago White Sox vs Seattle Mariners

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Chicago White Sox vs Seattle Mariners Picks