Philadelphia Phillies vs Chicago White Sox Prediction & Picks - MLB
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by Lou Aguila | in MLB Picks
The Chicago White Sox and the Philadelphia Phillies kick off their interleague play by sending two of their hottest pitchers to the mound.
The White Sox tapped lefty Anthony Kay (5-1, 3.77 ERA) to open the series against the Phillies. Kay has only given up five runs across his last five starts. He’s facing a Phillies team that is averaging 3.9 runs on a .213 BA against left-handed pitchers this season.
The Phillies countered by deploying Jesus Luzardo (4-4, 4.30 ERA). Luzardo has also posted a strong 3.08 ERA in his last five starts. He has surrendered only 4 runs and recorded two shutout stints in his last four starts. The Phillies lefty takes on a White Sox offense that is hitting .241 with 4.9 runs per game against left-handed hurlers.
Key Stats: Philadelphia starting pitchers have tossed a 3.58 ERA over the last 5 starts. The Chicago bullpen has recorded a 0.47 ERA over the last five games.
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Philadelphia Phillies vs Chicago White Sox Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
6
|
0.554 | 83 | 46 | 37 |
|
8
|
0.531 | 81 | 43 | 38 |
Philadelphia Phillies and Chicago White Sox Latest Matches
4/6 (67%)
2/6 (33%)
Jun 4, 2026 - MLB
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4/6 (67%)
2/6 (33%)
Jun 4, 2026 - MLB
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4/6 (67%)
2/6 (33%)
May 31, 2026 - MLB
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4/6 (67%)
2/6 (33%)
Jun 3, 2026 - MLB
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5/6 (83%)
1/6 (17%)
May 31, 2026 - MLB
May 30, 2026 - MLB
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2/6 (33%)
4/6 (67%)
Jun 3, 2026 - MLB
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Jun 1, 2026 - MLB
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Philadelphia Phillies against Chicago White Sox : Head to Head (H2H)
60 %
40 %
Jul 30, 2025 - MLB
Jul 29, 2025 - MLB
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Apr 21, 2024 - MLB
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Philadelphia Phillies - Chicago White Sox Key Points
- The total has gone UNDER in 10 of Philadelphia's last 12 games.
- The total has gone UNDER in 5 of Philadelphia's last 6 games at home.
- Phillies' LHP Jesus Luzardo has posted a 3.08 ERA in his last five starts
- White Sox LHP Anthony Kay has posted a 1.65 ERA in his last five starts
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Our Philadelphia Phillies vs Chicago White Sox Prediction
Despite the overwhelming offense from both squads, the quality of pitching – especially in the starters - in Game 1 will prevent the total from breaching 8.5 runs.
Kay and Luzardo should sustain their tip-top form to keep both offenses from running wild through the six or seven innings in the match. The late innings can be unpredictable, but I trust both bullpens will deliver the goods down the stretch.
Our betting prediction for the Philadelphia Phillies vs. the Chicago White Sox: Under 8.5 runs
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