Minnesota Twins vs Chicago White Sox Prediction & Picks - MLB

USA - MLB

Minnesota Twins
8/28/26 20:10
Chicago White Sox

Prediction:

 

Twins ML

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 by Travis Pulver | in MLB Picks

The Minnesota Twins (64-70, 35-31 Home) are running out of time to make a move and get into the playoffs.  Not only are they 6.5 back in the AL Central, but four games back for the last wild card spot. To that end, a win against their division rival, the Chicago White Sox (70-63, 29-36 Away) would certainly come in handy tonight.

Game time for this division rivalry is set for 8:10 p.m. EST at Target Field in Minneapolis, MN, with coverage provided by MLB.TV.

Dean Kremer is scheduled to start for the Twins today. Kremer is 2-4 on the season with a 5.22 ER but just a 1.18 WHIP. But since getting acquired by Minnesota, he has gone 1-0 in four starts with a 3.18 ERA. He faced the White Sox when he was still in Baltimore and pitched a solid game (six innings, four hits, one run allowed, and four strikeouts).

Chicago is expected to hand the ball to Luis Castillo. For the season, he is 4-10 with a 5.19 ERA and a 1.42 WHIP. Like Kremer, he was recently acquired by the White Sox. Since making the move, he has gone 1-1 in four starts with a 5.89 ERA.

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Minnesota Twins vs Chicago White Sox Form

Table

Teams Pts P W L
12 Chicago White Sox
0.519 162 84 78
19 Minnesota Twins
0.475 162 77 85

Minnesota Twins and Chicago White Sox Latest Matches

Minnesota Twins
Minnesota Twins Latest matches
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Aug 26, 2026 - MLB

Athletics
7 :  4
Minnesota Twins

Aug 25, 2026 - MLB

Athletics
4 :  2
Minnesota Twins

Aug 24, 2026 - MLB

Athletics
6 :  9
Minnesota Twins

Aug 23, 2026 - MLB

San Diego Padres
8 :  1
Minnesota Twins

Aug 22, 2026 - MLB

San Diego Padres
7 :  5
Minnesota Twins

Aug 21, 2026 - MLB

San Diego Padres
6 :  2
Minnesota Twins
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 19, 2026 - MLB

Minnesota Twins
6 :  4
Atlanta Braves

Aug 18, 2026 - MLB

Minnesota Twins
4 :  1
Atlanta Braves

Aug 17, 2026 - MLB

Minnesota Twins
4 :  2
Atlanta Braves

Aug 16, 2026 - MLB

Minnesota Twins
5 :  7
Philadelphia Phillies

Aug 15, 2026 - MLB

Minnesota Twins
1 :  9
Philadelphia Phillies

Aug 13, 2026 - MLB

Minnesota Twins
1 :  7
Philadelphia Phillies
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Aug 26, 2026 - MLB

Athletics
7 :  4
Minnesota Twins

Aug 25, 2026 - MLB

Athletics
4 :  2
Minnesota Twins

Aug 24, 2026 - MLB

Athletics
6 :  9
Minnesota Twins

Aug 23, 2026 - MLB

San Diego Padres
8 :  1
Minnesota Twins

Aug 22, 2026 - MLB

San Diego Padres
7 :  5
Minnesota Twins

Aug 21, 2026 - MLB

San Diego Padres
6 :  2
Minnesota Twins
Chicago White Sox
Chicago White Sox Latest matches
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 26, 2026 - MLB

Chicago White Sox
10 :  4
Texas Rangers

Aug 25, 2026 - MLB

Chicago White Sox
11 :  7
Texas Rangers

Aug 24, 2026 - MLB

Chicago White Sox
2 :  11
Texas Rangers

Aug 23, 2026 - MLB

Chicago White Sox
2 :  1
New York Mets

Aug 22, 2026 - MLB

Chicago White Sox
5 :  10
New York Mets

Aug 21, 2026 - MLB

Chicago White Sox
6 :  4
New York Mets
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 26, 2026 - MLB

Chicago White Sox
10 :  4
Texas Rangers

Aug 25, 2026 - MLB

Chicago White Sox
11 :  7
Texas Rangers

Aug 24, 2026 - MLB

Chicago White Sox
2 :  11
Texas Rangers

Aug 23, 2026 - MLB

Chicago White Sox
2 :  1
New York Mets

Aug 22, 2026 - MLB

Chicago White Sox
5 :  10
New York Mets

Aug 21, 2026 - MLB

Chicago White Sox
6 :  4
New York Mets
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 19, 2026 - MLB

Chicago Cubs
0 :  3
Chicago White Sox

Aug 18, 2026 - MLB

Chicago Cubs
4 :  3
Chicago White Sox

Aug 17, 2026 - MLB

Chicago Cubs
7 :  5
Chicago White Sox

Aug 16, 2026 - MLB

Detroit Tigers
5 :  7
Chicago White Sox

Aug 15, 2026 - MLB

Detroit Tigers
3 :  4
Chicago White Sox

Aug 14, 2026 - MLB

Detroit Tigers
5 :  9
Chicago White Sox

Minnesota Twins against Chicago White Sox : Head to Head (H2H)

Minnesota Twins

50 %

Chicago White Sox

50 %

Jun 3, 2026 - MLB

Minnesota Twins
0 :  8
Chicago White Sox

Jun 2, 2026 - MLB

Minnesota Twins
6 :  4
Chicago White Sox

Jun 1, 2026 - MLB

Minnesota Twins
9 :  6
Chicago White Sox

May 28, 2026 - MLB

Chicago White Sox
6 :  2
Minnesota Twins

May 27, 2026 - MLB

Chicago White Sox
15 :  2
Minnesota Twins

May 26, 2026 - MLB

Chicago White Sox
3 :  5
Minnesota Twins
Minnesota Twins vs Chicago White Sox Picks

Minnesota Twins - Chicago White Sox Key Points

  1. Minnesota and Chicago have met 33 times over the last three seasons; the Twins won 20 to the White Sox's 13.
  2. Minnesota is 34-31 ATS (run line) at home this season; Chicago is 37-28 ATS (run line) on the road.
  3. The OVER is 30-31-4 for the Twins at home and 37-27-1 for the White Sox on the road.
  4. Betting Public: 47% of moneyline tickets and 39% of the handle are on the Twins.

Our Minnesota Twins vs Chicago White Sox Prediction

It is hard to have confidence in either pitcher, but I have much less in Castillo than I do Kremer. Kremer has been solid since joining the Twins and has a good history against White Sox hitters (.173, 9-52 with one home run and 11 Ks). Castillo was not great in Seattle, and a change of venue has not helped. He did have one brilliant outing against the Reds, but the other three were not good.

There is a good chance this ends up being a high-scoring game (OVER 9) because of unimpressive pitching and solid hitting. That also makes it hard to go with the run line. I see the Twins getting out to an early lead before Castillo gets pulled and holding on to win.

Our Chicago vs. Minnesota Pick: Twins ML

Prediction:

 

Twins ML

−124
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.