Houston Astros vs Chicago White Sox Prediction & Picks - MLB
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by Carlos Zabala in MLB Picks
On Thursday, the White Sox and Astros conclude their four-game series in Houston, a matchup between division leaders with the pressure of a strong September to secure their playoff berths.
The Astros took the first game 6-3, with Nelson Velazquez hitting a two-run homer and Cam Smith adding a two-run double. Game 2 went to the White Sox, who won 5-1; Colson Montgomery had two hits and two RBIs, and Grichuk hit an RBI double. The third game was a true pitching duel, remaining scoreless until the eighth inning.
At this point, the Astros are feeling the pressure from the Rangers' lead and face a tough start to September, with upcoming series against the Diamondbacks, Phillies, and Rays—all teams with winning records.
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Houston Astros vs Chicago White Sox Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
9
|
0.525 | 139 | 73 | 66 |
|
12
|
0.507 | 140 | 71 | 69 |
Houston Astros and Chicago White Sox Latest Matches
4/6 (67%)
2/6 (33%)
Sep 1, 2026 - MLB
Aug 31, 2026 - MLB
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Aug 27, 2026 - MLB
2/6 (33%)
4/6 (67%)
Sep 1, 2026 - MLB
Aug 31, 2026 - MLB
Aug 23, 2026 - MLB
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Aug 20, 2026 - MLB
4/6 (67%)
2/6 (33%)
Aug 30, 2026 - MLB
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Aug 25, 2026 - MLB
4/6 (67%)
2/6 (33%)
Sep 1, 2026 - MLB
Aug 31, 2026 - MLB
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Aug 26, 2026 - MLB
4/6 (67%)
2/6 (33%)
Aug 26, 2026 - MLB
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Aug 21, 2026 - MLB
4/6 (67%)
2/6 (33%)
Sep 1, 2026 - MLB
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Houston Astros against Chicago White Sox : Head to Head (H2H)
67 %
33 %
Sep 1, 2026 - MLB
Aug 31, 2026 - MLB
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Jun 12, 2025 - MLB
Houston Astros - Chicago White Sox Key Points
- Astros pitching K/9 ratio, ninth best in MLB
- Astros FDL%, eighth best in MLB at .987
- Astros second-fewest stolen bases this season
- White Sox road record 32-38 this season
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Our Houston Astros vs Chicago White Sox Prediction
Luis Castillo, acquired from the Mariners before the trade deadline, will pitch for the White Sox in the final game of the series. The Dominican has extensive experience facing the Astros lineup, but is coming off an outing in which he allowed 8 hits and 4 runs against the Twins.
Hunter Brown will pitch for the Astros; he pitched decisively in his last start, recording 10 strikeouts and earning the win in his team's 3-1 victory over the Mets.
Our prediction for Astros vs White Sox is: Astros ML.
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