Houston Astros vs Chicago White Sox Prediction & Picks - MLB

USA - MLB

Houston Astros
9/2/26 20:10
Chicago White Sox

Prediction:

 

Over 8.5 Total Runs

-105
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 by Matt Lowrimore | in MLB Picks

A full 15-game MLB slate is scheduled for Wednesday, one of which will include an American League matchup between the Houston Astros and the Chicago White Sox. Let’s take a look at the match statistics and predictions for this game between the Astros and the White Sox.

Chicago enters this game several games over .500 and is currently in first place in the American League Central Division. Set to start this game for the White Sox will be Davis Martin, who has a record of 9-6 and an ERA of 4.32. Martin has not been consistent on the road this season, suggesting even the Astros’ offense will be able to take advantage.

As for Houston, they enter this game only a couple of games above .500, but are currently in first place in the American League West division. Starting this game for the Astros will be Hayden Wesneski, who has a record of 4-1 and an ERA of 3.86. Despite his decent numbers overall, Wesneski has not fared well at home this season, which tells us the White Sox could also have success offensively.

Houston Astros vs Chicago White Sox Form

Table

Teams Pts P W L
9 Chicago White Sox
0.529 138 73 65
13 Houston Astros
0.504 139 70 69

Houston Astros and Chicago White Sox Latest Matches

Houston Astros
Houston Astros Latest matches
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 1, 2026 - MLB

Houston Astros
1 :  5
Chicago White Sox

Aug 31, 2026 - MLB

Houston Astros
6 :  3
Chicago White Sox

Aug 30, 2026 - MLB

New York Mets
3 :  6
Houston Astros

Aug 29, 2026 - MLB

New York Mets
6 :  2
Houston Astros

Aug 28, 2026 - MLB

New York Mets
1 :  3
Houston Astros

Aug 27, 2026 - MLB

New York Yankees
1 :  5
Houston Astros
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 1, 2026 - MLB

Houston Astros
1 :  5
Chicago White Sox

Aug 31, 2026 - MLB

Houston Astros
6 :  3
Chicago White Sox

Aug 23, 2026 - MLB

Houston Astros
6 :  7
Athletics

Aug 22, 2026 - MLB

Houston Astros
3 :  4
Athletics

Aug 21, 2026 - MLB

Houston Astros
4 :  0
Athletics

Aug 20, 2026 - MLB

Houston Astros
3 :  18
Los Angeles Angels
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 30, 2026 - MLB

New York Mets
3 :  6
Houston Astros

Aug 29, 2026 - MLB

New York Mets
6 :  2
Houston Astros

Aug 28, 2026 - MLB

New York Mets
1 :  3
Houston Astros

Aug 27, 2026 - MLB

New York Yankees
1 :  5
Houston Astros

Aug 26, 2026 - MLB

New York Yankees
9 :  3
Houston Astros

Aug 25, 2026 - MLB

New York Yankees
7 :  9
Houston Astros
Chicago White Sox
Chicago White Sox Latest matches
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 1, 2026 - MLB

Houston Astros
1 :  5
Chicago White Sox

Aug 31, 2026 - MLB

Houston Astros
6 :  3
Chicago White Sox

Aug 30, 2026 - MLB

Minnesota Twins
5 :  1
Chicago White Sox

Aug 29, 2026 - MLB

Minnesota Twins
2 :  3
Chicago White Sox

Aug 28, 2026 - MLB

Minnesota Twins
4 :  7
Chicago White Sox

Aug 26, 2026 - MLB

Chicago White Sox
10 :  4
Texas Rangers
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 26, 2026 - MLB

Chicago White Sox
10 :  4
Texas Rangers

Aug 25, 2026 - MLB

Chicago White Sox
11 :  7
Texas Rangers

Aug 24, 2026 - MLB

Chicago White Sox
2 :  11
Texas Rangers

Aug 23, 2026 - MLB

Chicago White Sox
2 :  1
New York Mets

Aug 22, 2026 - MLB

Chicago White Sox
5 :  10
New York Mets

Aug 21, 2026 - MLB

Chicago White Sox
6 :  4
New York Mets
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 1, 2026 - MLB

Houston Astros
1 :  5
Chicago White Sox

Aug 31, 2026 - MLB

Houston Astros
6 :  3
Chicago White Sox

Aug 30, 2026 - MLB

Minnesota Twins
5 :  1
Chicago White Sox

Aug 29, 2026 - MLB

Minnesota Twins
2 :  3
Chicago White Sox

Aug 28, 2026 - MLB

Minnesota Twins
4 :  7
Chicago White Sox

Aug 19, 2026 - MLB

Chicago Cubs
0 :  3
Chicago White Sox

Houston Astros against Chicago White Sox : Head to Head (H2H)

Houston Astros

67 %

Chicago White Sox

33 %

Sep 1, 2026 - MLB

Houston Astros
1 :  5
Chicago White Sox

Aug 31, 2026 - MLB

Houston Astros
6 :  3
Chicago White Sox

Jul 26, 2026 - MLB

Chicago White Sox
12 :  3
Houston Astros

Jul 25, 2026 - MLB

Chicago White Sox
1 :  4
Houston Astros

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jun 12, 2025 - MLB

Houston Astros
4 :  3
Chicago White Sox
Houston Astros vs Chicago White Sox Picks

Houston Astros - Chicago White Sox Key Points

  1. Davis Martin has an ERA of 4.32 this season
  2. Davis Martin has an ERA of 5.32 on the road this season
  3. Hayden Wesneski has an ERA of 3.86 this season
  4. Hayden Wesneski has an ERA of 4.20 at home this season

Our Houston Astros vs Chicago White Sox Prediction

Houston is the small favorite in this game; however, the over looks to be the best betting option. This goes directly to the home/away splits between the two starting pitchers. Martin has made 12 away starts this season, in which he has allowed 39 earned runs over 66.0 innings. Wesneski, on the other hand, has made three home starts, having allowed seven earned runs over 15.0 innings. 

Even though both teams have been inconsistent at times throughout the season, they both have top-10 offenses. For that reason, our Houston Astros vs Chicago White Sox prediction is: Over 8.5 Total Runs.

Prediction:

 

Over 8.5 Total Runs

-105
$350 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.