Houston Astros vs Chicago White Sox Prediction & Picks - MLB
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by Matt Lowrimore | in MLB Picks
A full 15-game MLB slate is scheduled for Wednesday, one of which will include an American League matchup between the Houston Astros and the Chicago White Sox. Let’s take a look at the match statistics and predictions for this game between the Astros and the White Sox.
Chicago enters this game several games over .500 and is currently in first place in the American League Central Division. Set to start this game for the White Sox will be Davis Martin, who has a record of 9-6 and an ERA of 4.32. Martin has not been consistent on the road this season, suggesting even the Astros’ offense will be able to take advantage.
As for Houston, they enter this game only a couple of games above .500, but are currently in first place in the American League West division. Starting this game for the Astros will be Hayden Wesneski, who has a record of 4-1 and an ERA of 3.86. Despite his decent numbers overall, Wesneski has not fared well at home this season, which tells us the White Sox could also have success offensively.
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Houston Astros vs Chicago White Sox Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
9
|
0.529 | 138 | 73 | 65 |
|
13
|
0.504 | 139 | 70 | 69 |
Houston Astros and Chicago White Sox Latest Matches
4/6 (67%)
2/6 (33%)
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2/6 (33%)
4/6 (67%)
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4/6 (67%)
2/6 (33%)
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4/6 (67%)
2/6 (33%)
Sep 1, 2026 - MLB
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4/6 (67%)
2/6 (33%)
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4/6 (67%)
2/6 (33%)
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Houston Astros against Chicago White Sox : Head to Head (H2H)
67 %
33 %
Sep 1, 2026 - MLB
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Houston Astros - Chicago White Sox Key Points
- Davis Martin has an ERA of 4.32 this season
- Davis Martin has an ERA of 5.32 on the road this season
- Hayden Wesneski has an ERA of 3.86 this season
- Hayden Wesneski has an ERA of 4.20 at home this season
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Our Houston Astros vs Chicago White Sox Prediction
Houston is the small favorite in this game; however, the over looks to be the best betting option. This goes directly to the home/away splits between the two starting pitchers. Martin has made 12 away starts this season, in which he has allowed 39 earned runs over 66.0 innings. Wesneski, on the other hand, has made three home starts, having allowed seven earned runs over 15.0 innings.
Even though both teams have been inconsistent at times throughout the season, they both have top-10 offenses. For that reason, our Houston Astros vs Chicago White Sox prediction is: Over 8.5 Total Runs.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.