Cleveland Guardians vs Chicago White Sox Prediction & Picks - MLB
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by Lou Aguila in MLB Picks
The Cleveland Guardians eye their third straight win against the Chicago White Sox in Game 2 of their series. Cleveland carries an 8-0 record in their last 8 home games against the White Sox.
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The Cleveland Guardians won their last two games, including the opener against the White Sox 6-5. Cleveland owns a 46-42 record and shares the top spot in the AL Central with the White Sox (45-41).
The Chicago White Sox have lost their last two games and three of their last five. Although rookie sensation Munetaka Murakami remains on the IL with a hamstring injury, the White Sox’s offense stays potent, averaging 5.4 runs on a .243 BA over the last five games.
Starting Pitchers:
White Sox LHP Anthony Kay (6-3, 4.50 ERA) recorded four earned runs over 3.2 innings in a 4-5 loss to Kansas on June 28.
Guardians RHP Gavin Williams (9-4, 3.81 ERA) surrendered two earned runs over 5.0 innings in a 6-5 win over Seattle on June 28.
The Matchup: The Guardians are 7-3 in their last 10 meetings with the White Sox. Cleveland is also 8-0 SU in its last 8 home games against the Chicago White Sox.
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Cleveland Guardians vs Chicago White Sox Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
9
|
0.523 | 86 | 45 | 41 |
|
9
|
0.523 | 88 | 46 | 42 |
Cleveland Guardians and Chicago White Sox Latest Matches
4/6 (67%)
2/6 (33%)
Jul 2, 2026 - MLB
Jul 1, 2026 - MLB
Jun 30, 2026 - MLB
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4/6 (67%)
2/6 (33%)
Jul 2, 2026 - MLB
Jul 1, 2026 - MLB
Jun 30, 2026 - MLB
Jun 29, 2026 - MLB
Jun 28, 2026 - MLB
Jun 27, 2026 - MLB
2/6 (33%)
4/6 (67%)
Jun 24, 2026 - MLB
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3/6 (50%)
3/6 (50%)
Jul 2, 2026 - MLB
Jul 1, 2026 - MLB
Jun 30, 2026 - MLB
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Jun 27, 2026 - MLB
4/6 (67%)
2/6 (33%)
Jun 28, 2026 - MLB
Jun 27, 2026 - MLB
Jun 26, 2026 - MLB
Jun 24, 2026 - MLB
Jun 23, 2026 - MLB
Jun 22, 2026 - MLB
2/6 (33%)
4/6 (67%)
Jul 2, 2026 - MLB
Jul 1, 2026 - MLB
Jun 30, 2026 - MLB
Jun 29, 2026 - MLB
Jun 21, 2026 - MLB
Jun 20, 2026 - MLB
Cleveland Guardians against Chicago White Sox : Head to Head (H2H)
50 %
50 %
Jul 2, 2026 - MLB
Jun 24, 2026 - MLB
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Mar 5, 2026 - MLB Spring Training
Feb 28, 2026 - MLB Spring Training
Cleveland Guardians - Chicago White Sox Key Points
- Chicago White Sox is 4-16 SU in its last 20 games against Cleveland.
- Cleveland is 8-0 SU in its last 8 games when playing at home against Chicago White Sox.
- Cleveland is 4-2 SU in its last 6 games.
- Chicago White Sox is 3-8 SU in its last 11 games on the road.
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Our Cleveland Guardians vs Chicago White Sox Prediction
Fearless Forecast: The Guardians extend their win streak to three with another close win over the White Sox, 7-6
The Difference Maker: Cleveland averages at least 5.0 runs per game over its last five games. Moreover, projected starter Gavin Williams has not allowed more than three runs in his last three starts against the White Sox.
While Chicago’s offence remains productive, it's obvious that they are missing Murakami’s power-hitting, which made the team so lethal offensively during the first half of the season.
What to Expect: The Guardians sustained their mastery over the White Sox at home, getting key contributions from Chase DeLauter, Angel Martinez and Brayan Rocchio.
Guardians’ Gavin Williams and White Sox’ Anthony Kay each posted quality starts, but Cleveland’s bullpen (3.72 ERA at home) pulled all the stops again to help their team edge the visitors.
Our betting prediction for the Chicago White Sox vs. the Cleveland Guardians: The Guardians will win
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