Cleveland Guardians vs Chicago White Sox Prediction & Picks - MLB

USA - MLB

Cleveland Guardians
4/10/25 13:10
Chicago White Sox

Prediction:

 

Guardians will cover -1.5 Runs

+100
$200 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Lou Aguila | in MLB Picks

The Cleveland Guardians marched into Progressive Field on Thursday, aiming for a three-game sweep of the Chicago White Sox.

The Guardians have won three of their last five games, including two straight at the expense of the White Sox. Cleveland demonstrated impeccable pitching in the last two games, limiting Chicago to a total of three runs across 18 innings. Cleveland, who is pitching a 3.98 ERA in their last five games, will be dispatching Garvin Williams (1-4, 4.29 in last five start).

The White Sox have lost their last seven games after a 2-2 start. Chicago isn’t pitching that bad in the series, as they have hounded the Guardians to just four runs between Game 1 and 2, but their offense has been flat-out dreadful. In their last five games, Chicago has averaged 2.2 runs per game on a .190 batting average.

Cleveland Guardians vs Chicago White Sox Form

Table

Teams Pts P W L
10 Cleveland Guardians
0.543 162 88 74
29 Chicago White Sox
0.37 162 60 102

Cleveland Guardians and Chicago White Sox Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 9, 2025 - MLB

Cleveland Guardians
3 :  2
Chicago White Sox

Apr 8, 2025 - MLB

Cleveland Guardians
1 :  0
Chicago White Sox

Apr 6, 2025 - MLB

Los Angeles Angels
6 :  2
Cleveland Guardians

Apr 5, 2025 - MLB

Los Angeles Angels
10 :  4
Cleveland Guardians

Apr 4, 2025 - MLB

Los Angeles Angels
6 :  8
Cleveland Guardians

Apr 2, 2025 - MLB

San Diego Padres
5 :  2
Cleveland Guardians
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 9, 2025 - MLB

Cleveland Guardians
3 :  2
Chicago White Sox

Apr 8, 2025 - MLB

Cleveland Guardians
1 :  0
Chicago White Sox

Oct 19, 2024 - MLB

Cleveland Guardians
2 :  5
New York Yankees

Oct 18, 2024 - MLB

Cleveland Guardians
6 :  8
New York Yankees

Oct 17, 2024 - MLB

Cleveland Guardians
7 :  5
New York Yankees

Oct 12, 2024 - MLB

Cleveland Guardians
7 :  3
Detroit Tigers
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 6, 2025 - MLB

Los Angeles Angels
6 :  2
Cleveland Guardians

Apr 5, 2025 - MLB

Los Angeles Angels
10 :  4
Cleveland Guardians

Apr 4, 2025 - MLB

Los Angeles Angels
6 :  8
Cleveland Guardians

Apr 2, 2025 - MLB

San Diego Padres
5 :  2
Cleveland Guardians

Apr 1, 2025 - MLB

San Diego Padres
7 :  0
Cleveland Guardians

Mar 31, 2025 - MLB

San Diego Padres
7 :  2
Cleveland Guardians
Chicago White Sox
Chicago White Sox Latest matches
L L L L L L
Victories

0/6 (0%)

Defeats

6/6 (100%)

Apr 9, 2025 - MLB

Cleveland Guardians
3 :  2
Chicago White Sox

Apr 8, 2025 - MLB

Cleveland Guardians
1 :  0
Chicago White Sox

Apr 6, 2025 - MLB

Detroit Tigers
4 :  3
Chicago White Sox

Apr 5, 2025 - MLB

Detroit Tigers
7 :  2
Chicago White Sox

Apr 4, 2025 - MLB

Detroit Tigers
7 :  4
Chicago White Sox

Apr 2, 2025 - MLB

Chicago White Sox
1 :  6
Minnesota Twins
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 2, 2025 - MLB

Chicago White Sox
1 :  6
Minnesota Twins

Apr 1, 2025 - MLB

Chicago White Sox
3 :  8
Minnesota Twins

Mar 31, 2025 - MLB

Chicago White Sox
9 :  0
Minnesota Twins

Mar 30, 2025 - MLB

Chicago White Sox
2 :  3
Los Angeles Angels

Mar 29, 2025 - MLB

Chicago White Sox
0 :  1
Los Angeles Angels

Mar 27, 2025 - MLB

Chicago White Sox
8 :  1
Los Angeles Angels
W L L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 9, 2025 - MLB

Cleveland Guardians
3 :  2
Chicago White Sox

Apr 8, 2025 - MLB

Cleveland Guardians
1 :  0
Chicago White Sox

Apr 6, 2025 - MLB

Detroit Tigers
4 :  3
Chicago White Sox

Apr 5, 2025 - MLB

Detroit Tigers
7 :  2
Chicago White Sox

Apr 4, 2025 - MLB

Detroit Tigers
7 :  4
Chicago White Sox

Sep 29, 2024 - MLB

Detroit Tigers
5 :  9
Chicago White Sox

Cleveland Guardians against Chicago White Sox : Head to Head (H2H)

Cleveland Guardians

83 %

Chicago White Sox

17 %

Apr 9, 2025 - MLB

Cleveland Guardians
3 :  2
Chicago White Sox

Apr 8, 2025 - MLB

Cleveland Guardians
1 :  0
Chicago White Sox

Sep 9, 2024 - MLB

Chicago White Sox
3 :  5
Cleveland Guardians

Jul 4, 2024 - MLB

Cleveland Guardians
8 :  4
Chicago White Sox

Jul 3, 2024 - MLB

Cleveland Guardians
2 :  8
Chicago White Sox

Jul 2, 2024 - MLB

Cleveland Guardians
7 :  6
Chicago White Sox

Cleveland Guardians - Chicago White Sox Key Points

  1. Chicago White Sox are 0-6 SU in their last 6 games against Cleveland.
  2. Chicago White Sox are 0-7 SU in their last 7 games.
  3. Cleveland are 5-1 SU in their last 6 games when playing at home against Chicago White Sox.
  4. Cleveland are 4-2 SU in their last 6 games against an opponent in the American League.

Our Cleveland Guardians vs Chicago White Sox Prediction

The White Sox got a serviceable pitcher for Game 3 in Jonathan Cannon, who is 2-3 with a 3.76 ERA in his last five starts. Cannon allowed three runs in his last starts vs. the Tigers (4-7 loss) but had blanked the LA Angels in 5.0 innings in his season debut last March 29. Cannon is a solid pitcher, but I am unsure if he can carry Chicago to a win in Game 3 because they are disappointing on offense.

The Guardians have won their last six meetings for multiple reasons. And that same set of reasons will guide Cleveland to their most convincing series win over the hapless White Sox. Our betting prediction for Chicago White Sox vs. Cleveland Guardians: Cleveland Guardians will cover -1.5 Runs.

Prediction:

 

Guardians will cover -1.5 Runs

+100
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Cleveland Guardians vs Chicago White Sox Picks