Chicago Cubs vs Chicago White Sox Prediction & Picks - MLB

USA - MLB

Chicago Cubs
8/17/26 20:05
Chicago White Sox

Prediction:

 

Chicago Cubs ML

-162
$1000 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Matt Lowrimore in MLB Picks

An 11-game MLB slate is scheduled for Monday, which will include an Interleague and cross-city rivalry between the Chicago Cubs and the Chicago White Sox. Let’s take a look at the match statistics and predictions for this game between the Cubs and the White Sox.

The White Sox enter this game several games over .500 and are currently in first place in the American League Central Division. Starting this game for the White Sox will be Luis Castillo, who has a record of 4-9 and an ERA of 4.96. It is worth noting that Castillo has not performed well on the road this season, which should give the Cubs’ offense the chance to do some damage.

As for the Cubs, they enter this game with a top-5 record in the league, but are currently in second place in the National League Central division. Set to start this game for the Cubs will be Shota Imanaga, who has a record of 8-9 and an ERA of 3.74. Imanaga has been serviceable at home this season, suggesting he can do the same against the White Sox offense.

Chicago Cubs vs Chicago White Sox Form

Table

Teams Pts P W L
5 Chicago Cubs
0.576 125 72 53
10 Chicago White Sox
0.528 123 65 58

Chicago Cubs and Chicago White Sox Latest Matches

Chicago Cubs
Chicago Cubs Latest matches
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 16, 2026 - MLB

Chicago Cubs
4 :  11
St. Louis Cardinals

Aug 15, 2026 - MLB

Chicago Cubs
4 :  8
St. Louis Cardinals

Aug 14, 2026 - MLB

Chicago Cubs
3 :  0
St. Louis Cardinals

Aug 13, 2026 - MLB

Washington Nationals
7 :  0
Chicago Cubs

Aug 12, 2026 - MLB

Washington Nationals
6 :  12
Chicago Cubs

Aug 11, 2026 - MLB

Washington Nationals
6 :  8
Chicago Cubs
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 16, 2026 - MLB

Chicago Cubs
4 :  11
St. Louis Cardinals

Aug 15, 2026 - MLB

Chicago Cubs
4 :  8
St. Louis Cardinals

Aug 14, 2026 - MLB

Chicago Cubs
3 :  0
St. Louis Cardinals

Aug 6, 2026 - MLB

Chicago Cubs
3 :  2
Toronto Blue Jays

Aug 5, 2026 - MLB

Chicago Cubs
7 :  6
Los Angeles Dodgers

Aug 4, 2026 - MLB

Chicago Cubs
5 :  1
Los Angeles Dodgers
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 13, 2026 - MLB

Washington Nationals
7 :  0
Chicago Cubs

Aug 12, 2026 - MLB

Washington Nationals
6 :  12
Chicago Cubs

Aug 11, 2026 - MLB

Washington Nationals
6 :  8
Chicago Cubs

Aug 9, 2026 - MLB

Kansas City Royals
2 :  10
Chicago Cubs

Aug 8, 2026 - MLB

Kansas City Royals
6 :  3
Chicago Cubs

Aug 7, 2026 - MLB

Kansas City Royals
4 :  6
Chicago Cubs
Chicago White Sox
Chicago White Sox Latest matches
L W L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 16, 2026 - MLB

Detroit Tigers
5 :  7
Chicago White Sox

Aug 15, 2026 - MLB

Detroit Tigers
3 :  4
Chicago White Sox

Aug 14, 2026 - MLB

Detroit Tigers
5 :  9
Chicago White Sox

Aug 13, 2026 - MLB

Chicago White Sox
8 :  9
Cincinnati Reds

Aug 12, 2026 - MLB

Chicago White Sox
5 :  0
Cincinnati Reds

Aug 11, 2026 - MLB

Chicago White Sox
4 :  5
Cincinnati Reds
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 13, 2026 - MLB

Chicago White Sox
8 :  9
Cincinnati Reds

Aug 12, 2026 - MLB

Chicago White Sox
5 :  0
Cincinnati Reds

Aug 11, 2026 - MLB

Chicago White Sox
4 :  5
Cincinnati Reds

Aug 9, 2026 - MLB

Chicago White Sox
5 :  3
Cleveland Guardians

Aug 8, 2026 - MLB

Chicago White Sox
6 :  3
Cleveland Guardians

Aug 7, 2026 - MLB

Chicago White Sox
2 :  8
Cleveland Guardians
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 16, 2026 - MLB

Detroit Tigers
5 :  7
Chicago White Sox

Aug 15, 2026 - MLB

Detroit Tigers
3 :  4
Chicago White Sox

Aug 14, 2026 - MLB

Detroit Tigers
5 :  9
Chicago White Sox

Aug 6, 2026 - MLB

Boston Red Sox
12 :  11
Chicago White Sox

Aug 5, 2026 - MLB

Boston Red Sox
4 :  0
Chicago White Sox

Aug 4, 2026 - MLB

Boston Red Sox
14 :  2
Chicago White Sox

Chicago Cubs against Chicago White Sox : Head to Head (H2H)

Chicago Cubs

17 %

Chicago White Sox

83 %

May 17, 2026 - MLB

Chicago White Sox
9 :  8
Chicago Cubs

May 16, 2026 - MLB

Chicago White Sox
8 :  3
Chicago Cubs

May 15, 2026 - MLB

Chicago White Sox
5 :  10
Chicago Cubs

Mar 13, 2026 - MLB Spring Training

Chicago White Sox
4 :  2
Chicago Cubs

Mar 1, 2026 - MLB Spring Training

Chicago Cubs
1 :  5
Chicago White Sox

Feb 20, 2026 - MLB Spring Training

Chicago Cubs
1 :  8
Chicago White Sox
Chicago Cubs vs Chicago White Sox Picks

Chicago Cubs - Chicago White Sox Key Points

  1. Luis Castillo has an ERA of 4.96 this season
  2. Luis Castillo has an ERA of 5.49 on the road this season
  3. Shota Imanaga has an ERA of 3.74 this season
  4. Shota Imanaga has an ERA of 3.81 at home this season

Our Chicago Cubs vs Chicago White Sox Prediction

The Cubs are the heavy favorite in this game; however, they still look to be the best betting option. This goes directly to the home/away splits between the two starting pitchers. Castillo has made 12 away starts this season, where he has allowed 43 runs (36 earned) over 59.0 innings. Imanaga, on the other hand, has made 14 home starts, in which he has allowed 35 earned runs over 82.2 innings.

Both teams are having great seasons; however, with Imanaga giving the Cubs the clear advantage on the mound, our Chicago Cubs vs Chicago White Sox prediction is: Chicago Cubs ML.

Prediction:

 

Chicago Cubs ML

-162
$1000 offered for betting!

Welcome Bonus for the Chicago Cubs vs Chicago White Sox match!

FanDuel Bet Resets

The MLB season is in full swing and FanDuel is offering some great promos during the season, including their welcome offer of $1000, which can be activated for this Chicago Cubs vs Chicago White Sox match! Simply sign up and place a first bet of at least $5. In case your be loses, FanDuel will issue you the amount of your wager (up to $200 max) as a bet reset token. You can do this during your first 5 days with FanDuel, earning a total of $1000 in bet reset tokens!

Remember, the offer is only open to new sign-ups!

$1000 in bonus bets for Chicago Cubs vs Chicago White Sox!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.