Boston Red Sox vs Chicago White Sox Prediction & Picks - MLB

USA - MLB

Boston Red Sox
8/5/26 19:10
Chicago White Sox

Prediction:

 

Under 8.5 Total Runs

-111
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 by Matt Lowrimore | in MLB Picks

A 15-game MLB slate is scheduled for Wednesday, one of which will feature an American League matchup between the Boston Red Sox and the Chicago White Sox. Let’s take a look at the match statistics and predictions for this game between the Red Sox and the White Sox.

Chicago enters this game well over .500 and is currently in first place in the American League Central division. For Game 2 of this series, the White Sox are scheduled to start Sean Burke, who has a record of 7-5 and an ERA of 3.04. Burke has particularly been good when pitching on the road, suggesting he will be able to limit the Boston offense.

As for Boston, they enter this game also with a record above .500 and are currently in third place in the American League East division. Set to start this game for the Red Sox will be Sonny Gray, who has a record of 13-2 and an ERA of 2.93. Gray’s strength has been when he pitches in Boston, further suggesting runs could be at a premium in this matchup.

Boston Red Sox vs Chicago White Sox Form

Table

Teams Pts P W L
7 Boston Red Sox
0.545 112 61 51
9 Chicago White Sox
0.527 112 59 53

Boston Red Sox and Chicago White Sox Latest Matches

Boston Red Sox
Boston Red Sox Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Aug 4, 2026 - MLB

Boston Red Sox
14 :  2
Chicago White Sox

Aug 2, 2026 - MLB

Los Angeles Dodgers
4 :  8
Boston Red Sox

Aug 1, 2026 - MLB

Los Angeles Dodgers
2 :  3
Boston Red Sox

Jul 31, 2026 - MLB

Los Angeles Dodgers
4 :  9
Boston Red Sox

Jul 30, 2026 - MLB

Athletics
4 :  5
Boston Red Sox

Jul 29, 2026 - MLB

Athletics
2 :  4
Boston Red Sox
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 4, 2026 - MLB

Boston Red Sox
14 :  2
Chicago White Sox

Jul 26, 2026 - MLB

Boston Red Sox
6 :  1
Toronto Blue Jays

Jul 25, 2026 - MLB

Boston Red Sox
0 :  6
Toronto Blue Jays

Jul 24, 2026 - MLB

Boston Red Sox
6 :  4
Toronto Blue Jays

Jul 22, 2026 - MLB

Boston Red Sox
1 :  5
Baltimore Orioles

Jul 22, 2026 - MLB

Boston Red Sox
6 :  3
Baltimore Orioles
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Aug 2, 2026 - MLB

Los Angeles Dodgers
4 :  8
Boston Red Sox

Aug 1, 2026 - MLB

Los Angeles Dodgers
2 :  3
Boston Red Sox

Jul 31, 2026 - MLB

Los Angeles Dodgers
4 :  9
Boston Red Sox

Jul 30, 2026 - MLB

Athletics
4 :  5
Boston Red Sox

Jul 29, 2026 - MLB

Athletics
2 :  4
Boston Red Sox

Jul 28, 2026 - MLB

Athletics
4 :  3
Boston Red Sox
Chicago White Sox
Chicago White Sox Latest matches
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 4, 2026 - MLB

Boston Red Sox
14 :  2
Chicago White Sox

Aug 2, 2026 - MLB

Tampa Bay Rays
1 :  9
Chicago White Sox

Aug 1, 2026 - MLB

Tampa Bay Rays
1 :  0
Chicago White Sox

Jul 31, 2026 - MLB

Tampa Bay Rays
1 :  6
Chicago White Sox

Jul 30, 2026 - MLB

Chicago White Sox
2 :  1
New York Yankees

Jul 29, 2026 - MLB

Chicago White Sox
6 :  5
New York Yankees
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 30, 2026 - MLB

Chicago White Sox
2 :  1
New York Yankees

Jul 29, 2026 - MLB

Chicago White Sox
6 :  5
New York Yankees

Jul 28, 2026 - MLB

Chicago White Sox
2 :  3
New York Yankees

Jul 27, 2026 - MLB

Chicago White Sox
5 :  9
New York Yankees

Jul 26, 2026 - MLB

Chicago White Sox
12 :  3
Houston Astros

Jul 25, 2026 - MLB

Chicago White Sox
1 :  4
Houston Astros
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 4, 2026 - MLB

Boston Red Sox
14 :  2
Chicago White Sox

Aug 2, 2026 - MLB

Tampa Bay Rays
1 :  9
Chicago White Sox

Aug 1, 2026 - MLB

Tampa Bay Rays
1 :  0
Chicago White Sox

Jul 31, 2026 - MLB

Tampa Bay Rays
1 :  6
Chicago White Sox

Jul 22, 2026 - MLB

Texas Rangers
2 :  4
Chicago White Sox

Jul 21, 2026 - MLB

Texas Rangers
10 :  0
Chicago White Sox

Boston Red Sox against Chicago White Sox : Head to Head (H2H)

Boston Red Sox

83 %

Chicago White Sox

17 %

Aug 4, 2026 - MLB

Boston Red Sox
14 :  2
Chicago White Sox

Jul 9, 2026 - MLB

Chicago White Sox
1 :  2
Boston Red Sox

Jul 8, 2026 - MLB

Chicago White Sox
0 :  5
Boston Red Sox

Jul 7, 2026 - MLB

Chicago White Sox
1 :  8
Boston Red Sox

Apr 21, 2025 - MLB

Boston Red Sox
4 :  2
Chicago White Sox

Apr 20, 2025 - MLB

Boston Red Sox
4 :  8
Chicago White Sox
Boston Red Sox vs Chicago White Sox Picks

Boston Red Sox - Chicago White Sox Key Points

  1. Sean Burke has an ERA of 3.04 this season
  2. Sean Burke has an ERA of 2.50 on the road this season
  3. Sonny Gray has an ERA of 2.93 this season
  4. Sonny Gray has an ERA of 2.72 at home this season

Our Boston Red Sox vs Chicago White Sox Prediction

The Red Sox are the small favorite in this game; however, the under looks to be the best betting option. Burke has made nine road appearances (seven starts), having allowed 15 runs (14 earned) over 50.1 innings. Gray, on the other hand, has made 10 home starts, in which he has allowed 17 earned runs over 56.1 innings.

Runs were scored early and often in Game 1 of the series on Tuesday, but with two starting pitchers who have been consistent all season, especially in terms of their home/away splits, our Boston Red Sox vs Chicago White Sox prediction is: Under 8.5 Total Runs.

Prediction:

 

Under 8.5 Total Runs

-111
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.