Boston Red Sox vs Chicago White Sox Prediction & Picks - MLB

USA - MLB

Boston Red Sox
4/21/25 11:10
Chicago White Sox

Prediction:

 

Red Sox -1.5 Runs

-130
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 by Lou Aguila | in MLB Picks

The Boston Red Sox will head into Monday’s matinee game against the Chicago White Sox, looking to win three out of four games in the series at Fenway Park.

The Red Sox have gained a bit of steam as of late, winning four of their last five games. Sunday’s 4-8 loss to the White Sox snapped their four-game winning streak, but Boston has nevertheless improved their hitting numbers over the weekend, raising their batting average to .246 with 104 runs this season.

The White Sox pulled off a come-from-behind win on Sunday after Brooks Baldwin’s sacrifice hit ignited four unanswered runs between the 7th and 9th inning to erase a 2-4 deficit. The White Sox earned only their fifth win of the year, but hope the comeback win would wake up their spirit and start competing for wins.

Boston Red Sox vs Chicago White Sox Form

Table

Teams Pts P W L
9 Boston Red Sox
0.549 162 89 73
29 Chicago White Sox
0.37 162 60 102

Boston Red Sox and Chicago White Sox Latest Matches

Boston Red Sox
Boston Red Sox Latest matches
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 20, 2025 - MLB

Boston Red Sox
4 :  8
Chicago White Sox

Apr 19, 2025 - MLB

Boston Red Sox
4 :  3
Chicago White Sox

Apr 18, 2025 - MLB

Boston Red Sox
10 :  3
Chicago White Sox

Apr 16, 2025 - MLB

Tampa Bay Rays
0 :  1
Boston Red Sox

Apr 15, 2025 - MLB

Tampa Bay Rays
4 :  7
Boston Red Sox

Apr 14, 2025 - MLB

Tampa Bay Rays
16 :  1
Boston Red Sox
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 20, 2025 - MLB

Boston Red Sox
4 :  8
Chicago White Sox

Apr 19, 2025 - MLB

Boston Red Sox
4 :  3
Chicago White Sox

Apr 18, 2025 - MLB

Boston Red Sox
10 :  3
Chicago White Sox

Apr 10, 2025 - MLB

Boston Red Sox
4 :  3
Toronto Blue Jays

Apr 9, 2025 - MLB

Boston Red Sox
1 :  2
Toronto Blue Jays

Apr 8, 2025 - MLB

Boston Red Sox
1 :  6
Toronto Blue Jays
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 16, 2025 - MLB

Tampa Bay Rays
0 :  1
Boston Red Sox

Apr 15, 2025 - MLB

Tampa Bay Rays
4 :  7
Boston Red Sox

Apr 14, 2025 - MLB

Tampa Bay Rays
16 :  1
Boston Red Sox

Apr 13, 2025 - MLB

Chicago White Sox
1 :  3
Boston Red Sox

Apr 12, 2025 - MLB

Chicago White Sox
3 :  2
Boston Red Sox

Apr 11, 2025 - MLB

Chicago White Sox
11 :  1
Boston Red Sox
Chicago White Sox
Chicago White Sox Latest matches
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 20, 2025 - MLB

Boston Red Sox
4 :  8
Chicago White Sox

Apr 19, 2025 - MLB

Boston Red Sox
4 :  3
Chicago White Sox

Apr 18, 2025 - MLB

Boston Red Sox
10 :  3
Chicago White Sox

Apr 17, 2025 - MLB

Chicago White Sox
0 :  8
Athletics

Apr 16, 2025 - MLB

Chicago White Sox
1 :  3
Athletics

Apr 15, 2025 - MLB

Chicago White Sox
3 :  12
Athletics
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 17, 2025 - MLB

Chicago White Sox
0 :  8
Athletics

Apr 16, 2025 - MLB

Chicago White Sox
1 :  3
Athletics

Apr 15, 2025 - MLB

Chicago White Sox
3 :  12
Athletics

Apr 13, 2025 - MLB

Chicago White Sox
1 :  3
Boston Red Sox

Apr 12, 2025 - MLB

Chicago White Sox
3 :  2
Boston Red Sox

Apr 11, 2025 - MLB

Chicago White Sox
11 :  1
Boston Red Sox
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 20, 2025 - MLB

Boston Red Sox
4 :  8
Chicago White Sox

Apr 19, 2025 - MLB

Boston Red Sox
4 :  3
Chicago White Sox

Apr 18, 2025 - MLB

Boston Red Sox
10 :  3
Chicago White Sox

Apr 10, 2025 - MLB

Cleveland Guardians
6 :  1
Chicago White Sox

Apr 9, 2025 - MLB

Cleveland Guardians
3 :  2
Chicago White Sox

Apr 8, 2025 - MLB

Cleveland Guardians
1 :  0
Chicago White Sox

Boston Red Sox against Chicago White Sox : Head to Head (H2H)

Boston Red Sox

50 %

Chicago White Sox

50 %

Apr 20, 2025 - MLB

Boston Red Sox
4 :  8
Chicago White Sox

Apr 19, 2025 - MLB

Boston Red Sox
4 :  3
Chicago White Sox

Apr 18, 2025 - MLB

Boston Red Sox
10 :  3
Chicago White Sox

Apr 13, 2025 - MLB

Chicago White Sox
1 :  3
Boston Red Sox

Apr 12, 2025 - MLB

Chicago White Sox
3 :  2
Boston Red Sox

Apr 11, 2025 - MLB

Chicago White Sox
11 :  1
Boston Red Sox

Boston Red Sox - Chicago White Sox Key Points

  1. Boston is 4-1 SU in its last 5 games.
  2. Boston is 5-2 SU in its last 7 games against an opponent in the American League.
  3. Chicago White Sox is 1-6 SU in its last 7 games.
  4. Chicago White Sox is 1-8 SU in its last 9 games on the road.

Our Boston Red Sox vs Chicago White Sox Prediction

Fearless Forecast: the Red Sox will bounce back in a big way, securing both the series and against the spread win.

The Red Sox will start Walker Buehler (2-1, 5.23 ERA) to close out the series against the White Sox with a bang. Despite the not-so-impressive ERA, Buehler has put the Red Sox in a position to win this season, especially in his last two starts, where he has allowed only three earned runs. White Sox’s starter Jonathan Cannon is fresh off a 4.1-inning shutout of the Oakland Athletics. But like what happened in that game, Cannon will probably get another L again because he can’t get enough run support from the White Sox sluggers. Boston is 4-1 SU in its last 5 games. Our betting prediction for Chicago White Sox vs. Boston Red Sox: Red Sox will cover -1.5 runs.

Prediction:

 

Red Sox -1.5 Runs

-130
$350 offered for betting!

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Boston Red Sox vs Chicago White Sox Picks