Boston Red Sox vs Chicago White Sox Prediction & Picks - MLB

Prediction published on 4/19/25, 12:41 PM  by Travis Pulver | Modified on 1/13/26 at 9:53 AM in MLB Picks

The Chicago White Sox will try once again to get their first road win of the season when they take on the  Red Sox in Game Two of a four-game series at Fenway Park in Boston, MA. First pitch for this contest is scheduled for 4:10 p.m. EST.

Boston got to Chicago starting pitcher Martin Perez early in Friday’s game, chasing him after three innings, and recording five hits (one home run) and four earned runs off of him. The Chicago bullpen didn’t do much better, giving up six more hits and earned runs over the last six innings of the game. Hunter Dobbins gave the Red Sox six solid innings (three hits, two runs (one earned), and six strikeouts) to earn his second win of the season. The White Sox will turn to Shane Smith on the mound to start the game. Smith is 0-1 in three starts with a 2.04 ERA and a .91 WHIP; he’s received just four runs of support in his three starts. Boston will give the ball to Garrett Crochet to start the game. He’s 2-1 in four starts this season with a 1.38 ERA and .88 WHIP. Crochet went 7 1/3 innings in his last start, recording 11 strikeouts and allowing one hit.