St. Louis Cardinals vs Chicago Cubs Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Carlos Zabala | in MLB Picks
The Cubs secured their 60th win of the season at Busch Stadium against their longtime rivals, the Cardinals, defeating them 7-3 on Monday. The series continues on Tuesday; Game 2 is considered a very close matchup.
On Monday, Bregman went 4-for-5 with a home run, as did Nico Hoerner, whose homer to left field drove in Bregman. This continues Chicago's strong performance at the plate, as they have scored 25 runs in their last three games. Manager Counsell is thrilled with his team's performance; he stated that in this 162-game season, you can't fake your record, so those who make the playoffs have truly earned it.
The Cardinals-Cubs series now stands at 4-3 in favor of St. Louis; for the Cardinals, Winn and Bryan Torres drove in runs on Monday for the team, which now has a 53-53 record. Liberatore pitched only 3.2 innings before being pulled after allowing eight hits.
Limited Offer. Currently at DraftKings
St. Louis Cardinals vs Chicago Cubs Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
5
|
0.58 | 119 | 69 | 50 |
|
14
|
0.5 | 118 | 59 | 59 |
St. Louis Cardinals and Chicago Cubs Latest Matches
2/6 (33%)
4/6 (67%)
Jul 27, 2026 - MLB
Jul 26, 2026 - MLB
Jul 25, 2026 - MLB
Jul 24, 2026 - MLB
Jul 23, 2026 - MLB
Jul 22, 2026 - MLB
1/6 (17%)
5/6 (83%)
Jul 27, 2026 - MLB
Jul 26, 2026 - MLB
Jul 25, 2026 - MLB
Jul 24, 2026 - MLB
Jul 23, 2026 - MLB
Jul 12, 2026 - MLB
2/6 (33%)
4/6 (67%)
Jul 22, 2026 - MLB
Jul 21, 2026 - MLB
Jul 20, 2026 - MLB
Jul 19, 2026 - MLB
Jul 18, 2026 - MLB
Jul 17, 2026 - MLB
4/6 (67%)
2/6 (33%)
Jul 27, 2026 - MLB
Jul 26, 2026 - MLB
Jul 25, 2026 - MLB
Jul 24, 2026 - MLB
Jul 22, 2026 - MLB
Jul 21, 2026 - MLB
3/6 (50%)
3/6 (50%)
Jul 22, 2026 - MLB
Jul 21, 2026 - MLB
Jul 20, 2026 - MLB
Jul 19, 2026 - MLB
Jul 18, 2026 - MLB
Jul 17, 2026 - MLB
5/6 (83%)
1/6 (17%)
Jul 27, 2026 - MLB
Jul 26, 2026 - MLB
Jul 25, 2026 - MLB
Jul 24, 2026 - MLB
Jul 12, 2026 - MLB
Jul 11, 2026 - MLB
St. Louis Cardinals against Chicago Cubs : Head to Head (H2H)
50 %
50 %
Jul 27, 2026 - MLB
Jul 5, 2026 - MLB
Jul 4, 2026 - MLB
Jul 3, 2026 - MLB
May 31, 2026 - MLB
May 30, 2026 - MLB
St. Louis Cardinals - Chicago Cubs Key Points
- The Cubs are second in MLB in runs per game with 5.2
- The Cubs have a 30-24 road record this season
- The Cubs have a collective batting average of .281 over their last 10 games
- The Cardinals have a 27-30 record at Busch Stadium this season
Limited Offer. Currently at DraftKings
Our St. Louis Cardinals vs Chicago Cubs Prediction
Rea will start for the Cubs on Tuesday, but he's struggling to keep the ball in the park. The right-hander has allowed at least one home run in each of his last four starts and two in his most recent outing.
McGreevy will start for the Cardinals. He has a 4.70 ERA against the Cubs, and Ian Happ is 4-for-8 against him in his career. He will, of course, face Crow-Armstrong, who has 23 home runs this season, and Seiya Suzuki, who has three home runs since July 20.
Our prediction for Cardinals vs Cubs is: Over 9 runs.
A Welcome Bonus for St. Louis Cardinals vs Chicago Cubs!

Looking to place a bet on St. Louis Cardinals vs Chicago Cubs? For this MLB match, DraftKings will treat you to an exclusive offer: $150 in bonus bets, no promo code needed! Take advantage while you still can!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.