St. Louis Cardinals vs Chicago Cubs Prediction & Picks - MLB

USA - MLB

St. Louis Cardinals
8/9/25 19:15
Chicago Cubs

Prediction:

 

Cubs ML

-106
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 by Travis Pulver | in MLB Picks

The St. Louis Cardinals will try to make it three in a row today when they take on the visiting Chicago Cubs at Busch Stadium. Fans can follow the action in this NL Central division battle on Fox once the game gets underway at 7:15 p.m. EST.

St. Louis got on the board with a run in the bottom of the second, to make the score 1-0. With the pitching staff combining to throw a seven-hit shutout, that run ended up being all they needed. But the Cardinals tacked on four insurance runs to make the final 5-0. The win gives them the series lead vs. their NL Central rivals, 3-2. Colin Rea is scheduled to start for the Cubs. Rea has an 8-5 record in 23 appearances (19 starts) with an ERA of 4.23, WHIP of 1.32, and a .274 OBA. On the road, he has a 4.12 ERA in ten appearances (seven starts) with a .290 OBA. Andre Pallante is set to start for the Cardinals. Pallante is 6-8 this season in 22 starts with a 4.57 ERA, 1.32 WHIP, and .255 OBA. He’s been better at home, where he is 4-3 in ten starts with a 4.39 ERA and .245 OBA.

St. Louis Cardinals vs Chicago Cubs Form

Table

Teams Pts P W L
6 Chicago Cubs
0.568 162 92 70
20 St. Louis Cardinals
0.481 162 78 84

St. Louis Cardinals and Chicago Cubs Latest Matches

St. Louis Cardinals
St. Louis Cardinals Latest matches
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 6, 2025 - MLB

Los Angeles Dodgers
3 :  5
St. Louis Cardinals

Aug 5, 2025 - MLB

Los Angeles Dodgers
12 :  6
St. Louis Cardinals

Aug 4, 2025 - MLB

Los Angeles Dodgers
2 :  3
St. Louis Cardinals

Aug 2, 2025 - MLB

San Diego Padres
5 :  8
St. Louis Cardinals

Aug 1, 2025 - MLB

San Diego Padres
4 :  1
St. Louis Cardinals

Jul 28, 2025 - MLB

St. Louis Cardinals
7 :  1
Miami Marlins
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 28, 2025 - MLB

St. Louis Cardinals
7 :  1
Miami Marlins

Jul 26, 2025 - MLB

St. Louis Cardinals
1 :  3
San Diego Padres

Jul 24, 2025 - MLB

St. Louis Cardinals
9 :  7
San Diego Padres

Jul 12, 2025 - MLB

St. Louis Cardinals
6 :  7
Atlanta Braves

Jun 21, 2025 - MLB

St. Louis Cardinals
6 :  5
Cincinnati Reds

Jun 20, 2025 - MLB

St. Louis Cardinals
6 :  1
Cincinnati Reds
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 6, 2025 - MLB

Los Angeles Dodgers
3 :  5
St. Louis Cardinals

Aug 5, 2025 - MLB

Los Angeles Dodgers
12 :  6
St. Louis Cardinals

Aug 4, 2025 - MLB

Los Angeles Dodgers
2 :  3
St. Louis Cardinals

Aug 2, 2025 - MLB

San Diego Padres
5 :  8
St. Louis Cardinals

Aug 1, 2025 - MLB

San Diego Padres
4 :  1
St. Louis Cardinals

Jul 20, 2025 - MLB

Arizona Diamondbacks
5 :  3
St. Louis Cardinals
Chicago Cubs
Chicago Cubs Latest matches
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 6, 2025 - MLB

Chicago Cubs
6 :  1
Cincinnati Reds

Aug 5, 2025 - MLB

Chicago Cubs
1 :  5
Cincinnati Reds

Aug 2, 2025 - MLB

Chicago Cubs
3 :  4
Baltimore Orioles

Aug 1, 2025 - MLB

Chicago Cubs
1 :  0
Baltimore Orioles

Jul 30, 2025 - MLB

Milwaukee Brewers
3 :  10
Chicago Cubs

Jul 27, 2025 - MLB

Chicago White Sox
4 :  5
Chicago Cubs
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 6, 2025 - MLB

Chicago Cubs
6 :  1
Cincinnati Reds

Aug 5, 2025 - MLB

Chicago Cubs
1 :  5
Cincinnati Reds

Aug 2, 2025 - MLB

Chicago Cubs
3 :  4
Baltimore Orioles

Aug 1, 2025 - MLB

Chicago Cubs
1 :  0
Baltimore Orioles

Jul 22, 2025 - MLB

Chicago Cubs
6 :  0
Kansas City Royals

Jul 19, 2025 - MLB

Chicago Cubs
6 :  0
Boston Red Sox
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 30, 2025 - MLB

Milwaukee Brewers
3 :  10
Chicago Cubs

Jul 27, 2025 - MLB

Chicago White Sox
4 :  5
Chicago Cubs

Jul 25, 2025 - MLB

Chicago White Sox
12 :  5
Chicago Cubs

Jul 13, 2025 - MLB

New York Yankees
1 :  4
Chicago Cubs

Jul 12, 2025 - MLB

New York Yankees
2 :  5
Chicago Cubs

Jul 11, 2025 - MLB

New York Yankees
11 :  0
Chicago Cubs

St. Louis Cardinals against Chicago Cubs : Head to Head (H2H)

St. Louis Cardinals

17 %

Chicago Cubs

83 %

Jul 6, 2025 - MLB

Chicago Cubs
11 :  0
St. Louis Cardinals

Aug 2, 2024 - MLB

Chicago Cubs
6 :  3
St. Louis Cardinals

Aug 1, 2024 - MLB

Chicago Cubs
5 :  4
St. Louis Cardinals

Jul 12, 2024 - MLB

St. Louis Cardinals
1 :  5
Chicago Cubs

Jun 16, 2024 - MLB

Chicago Cubs
1 :  2
St. Louis Cardinals

Jun 15, 2024 - MLB

Chicago Cubs
5 :  1
St. Louis Cardinals
St. Louis Cardinals vs Chicago Cubs Picks

St. Louis Cardinals - Chicago Cubs Key Points

  1. The Cubs lead the all-time series vs. the Cardinals 1280-1225-19
  2. Rea faced the Cardinals on July 4 in Chicago; he went 6 2/3 innings, allowing two hits (one home run), two walks, and one earned run  along with four strikeouts.
  3. The Cubs' lineup has hit .310 against Pallante in 58 at-bats with three home runs (Michael Busch, Willi Castro, and Nico Hoerner).
  4. Betting Public: 71% of moneyline tickets and 83% of the handle are on the Cubs​​​​​​.

Our St. Louis Cardinals vs Chicago Cubs Prediction

With the win yesterday, the Cards have tied the season series up at 4-4. Colin Rea has done a solid, but unremarkable job. He’s given up two runs or less in five of his last seven starts, but has also given up 4+ in two of his last three. It’s hard to say how much support he’ll get with the lineup hitting just .223 over the last week. He’ll have his hands full against a St. Louis lineup hitting .284 over the last week. However, the Cubs have played well against Pallante in the past. This could be the breakout game they need to get out of their hitting rut.

I don’t have much confidence in either team, but the Cubs are the better of the two.

Our Cubs vs. Cardinals Pick: Chicago ML

Prediction:

 

Cubs ML

-106
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