San Francisco Giants vs Chicago Cubs Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Lou Aguila | in MLB Picks
Banking on their top-tier bullpen, the Chicago Cubs will attempt to sweep the San Francisco Giants on the road.
Momentum: The Chicago Cubs have won their last three games, including Games 1 (5-1) and 2 (6-1) of their series against the San Francisco Giants. As for the Giants, they have lost 4 of their last 5 game and are trying to prevent a sweep in their home field.
The Matchup: The Cubs have owned the Giants’ numbers lately, winning 3 of their last 4 meetings. Behind outstanding pitching, Chicago has restrained San Francisco to 1.3 runs per game while averaging 4.0 runs per contest over the last three head-to-head games.
Starting Pitchers: The Cubs will start relief pitcher Ryan Rolison on Sunday. Rollison has posted a 2.25 ERA over 20 mound appearances this season. He will be pitching against a San Francisco team that is hitting .258 with 3.8 runs per contest against left-handed pitchers this season.
The Giants tap Logan Webb to contain the Cubs’ offense. Webb has been pitching at an elite level, posting a 2.67 ERA over his last five starts while allowing one run or fewer in 4 of those outings.
Limited Offer. Currently at Caesars Sportsbook
San Francisco Giants vs Chicago Cubs Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
7
|
0.542 | 83 | 45 | 38 |
|
28
|
0.415 | 82 | 34 | 48 |
San Francisco Giants and Chicago Cubs Latest Matches
2/6 (33%)
4/6 (67%)
Jun 12, 2026 - MLB
Jun 10, 2026 - MLB
Jun 9, 2026 - MLB
Jun 8, 2026 - MLB
Jun 7, 2026 - MLB
Jun 6, 2026 - MLB
1/6 (17%)
5/6 (83%)
Jun 12, 2026 - MLB
Jun 10, 2026 - MLB
Jun 9, 2026 - MLB
Jun 8, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
4/6 (67%)
2/6 (33%)
Jun 7, 2026 - MLB
Jun 6, 2026 - MLB
Jun 5, 2026 - MLB
Jun 4, 2026 - MLB
Jun 3, 2026 - MLB
Jun 2, 2026 - MLB
3/6 (50%)
3/6 (50%)
Jun 12, 2026 - MLB
Jun 11, 2026 - MLB
Jun 10, 2026 - MLB
Jun 9, 2026 - MLB
Jun 7, 2026 - MLB
Jun 6, 2026 - MLB
2/6 (33%)
4/6 (67%)
Jun 7, 2026 - MLB
Jun 6, 2026 - MLB
Jun 5, 2026 - MLB
Jun 4, 2026 - MLB
Jun 3, 2026 - MLB
Jun 2, 2026 - MLB
3/6 (50%)
3/6 (50%)
Jun 12, 2026 - MLB
Jun 11, 2026 - MLB
Jun 10, 2026 - MLB
Jun 9, 2026 - MLB
May 31, 2026 - MLB
May 30, 2026 - MLB
San Francisco Giants against Chicago Cubs : Head to Head (H2H)
67 %
33 %
Jun 12, 2026 - MLB
Jun 7, 2026 - MLB
Jun 6, 2026 - MLB
Jun 5, 2026 - MLB
Mar 8, 2026 - MLB Spring Training
Feb 22, 2026 - MLB Spring Training
San Francisco Giants - Chicago Cubs Key Points
- San Francisco is 1-4 SU in its last 5 games.
- San Francisco is 1-7 SU in its last 8 games at home.
- Chicago Cubs is 9-4 SU in its last 13 games against an opponent in the National League West Division
- Chicago Cubs is 3-1 SU in its last 4 games against San Francisco
Limited Offer. Currently at Caesars Sportsbook
Our San Francisco Giants vs Chicago Cubs Prediction
The Cubs will strike late in the game to complete a sweep over the Giants.
San Francisco pitcher Logan Webb should be able to stifle the Cubs’ offense through six innings until the Giants' bullpen comes in and wastes another quality start.
The Giants’ relief pitchers have logged a 6.75 ERA over the last five games, which has left them vulnerable to comebacks and late-inning surges.
The Cubs, who average 1.8 home runs and 5.0 runs per game over their last five games, possess the weapons to score a barrage of runs at any point in a match.
Chicago also proved countless times this year that it can win ballgames by grinding down teams with strong pitching late in the game. The Cubs maintain a decent 4.73 ERA, while their bullpen is pitching to a rock-solid 3.50 ERA.
Our betting prediction for the Chicago Cubs vs. the San Francisco Giants: The Cubs will win.
A 2026 WC Welcome Bonus for San Francisco Giants vs Chicago Cubs!

Thanks to our code: STRADERDYW, you can unlock $250 available for use on this San Francisco Giants vs Chicago Cubs matchup!
This offer is only available for new sign-ups, but it remains one of the highest welcome bonuses currently on offer. Take advantage before it goes away!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.