San Francisco Giants vs Chicago Cubs Prediction & Picks - MLB

Prediction published on 8/28/25, 12:10 PM  by Lou Aguila | Modified on 9/1/25 at 1:07 AM in MLB Picks

The San Francisco Giants are expected to march into Thursday’s series finale with the Chicago Cubs as slight -108 home underdogs despite topping the visiting team in the first two games at Oracle Park.

The Giants are making their final push towards postseason qualification with barely four weeks left in the regular season. San Francisco is still three games below .500 at 65-68, but they are just seven games off the current holder of the No.3 wildcard spot in the National League, the 72-61 New York Mets. The Giants have put up strong numbers on both ends in their last five games, pitching a 2.82 ERA and averaging 6.7 runs per game.

Meanwhile, the Cubs’ pitching might have hardly been felt by the Giants in the first two games of this series. Chicago, boasting a 3.84 ERA in the season, surrendered five runs in Game 1 before squandering 12 runs in Game 2. The Cubs’ offensive firepower has noticeably diminished in the series, scoring a total of five runs after two games.