Los Angeles Dodgers vs Chicago Cubs Prediction & Picks - MLB

USA - MLB

Los Angeles Dodgers
4/25/26 19:15
Chicago Cubs

Prediction:

 

Over 8.5 runs.

-159
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 by Stephen Abiola | in MLB Picks

Los Angeles Dodgers (17-9) will host Chicago Cubs (17-9) in the second match of this three-game series on Saturday night. The Dodgers will be looking to bounce back from their 4-6 loss in the series opener on Friday night inside the sold-out Dodger Stadium. The Dodgers converted two exceptional outs at home, although the Cubs emerged as the better defensive team. The two-time defending champions will want to claw their way back into this series.

Chicago Cubs, on the other hand, will be brimming with confidence after their impressive display on Friday. Nico Hoerner and Dansby Swanson dazzled in defense, while Alex Bregman delivered his first big moment. This was Chicago’s tenth straight win, their longest winning streak since the 2016 title-winning season. The Cubs have been impressive so far despite having eight injured pitchers, with Caleb Thielbar joining the list on Friday with a hamstring strain.

Los Angeles Dodgers vs Chicago Cubs Form

Table

Teams Pts P W L
1 Los Angeles Dodgers
0.639 83 53 30
7 Chicago Cubs
0.542 83 45 38

Los Angeles Dodgers and Chicago Cubs Latest Matches

Los Angeles Dodgers
Los Angeles Dodgers Latest matches
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 23, 2026 - MLB

San Francisco Giants
0 :  3
Los Angeles Dodgers

Apr 22, 2026 - MLB

San Francisco Giants
3 :  0
Los Angeles Dodgers

Apr 21, 2026 - MLB

San Francisco Giants
3 :  1
Los Angeles Dodgers

Apr 20, 2026 - MLB

Colorado Rockies
3 :  12
Los Angeles Dodgers

Apr 19, 2026 - MLB

Colorado Rockies
9 :  6
Los Angeles Dodgers

Apr 18, 2026 - MLB

Colorado Rockies
4 :  3
Los Angeles Dodgers
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 15, 2026 - MLB

Los Angeles Dodgers
8 :  2
New York Mets

Apr 14, 2026 - MLB

Los Angeles Dodgers
2 :  1
New York Mets

Apr 13, 2026 - MLB

Los Angeles Dodgers
4 :  0
New York Mets

Apr 12, 2026 - MLB

Los Angeles Dodgers
2 :  5
Texas Rangers

Apr 11, 2026 - MLB

Los Angeles Dodgers
6 :  3
Texas Rangers

Apr 10, 2026 - MLB

Los Angeles Dodgers
8 :  7
Texas Rangers
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 23, 2026 - MLB

San Francisco Giants
0 :  3
Los Angeles Dodgers

Apr 22, 2026 - MLB

San Francisco Giants
3 :  0
Los Angeles Dodgers

Apr 21, 2026 - MLB

San Francisco Giants
3 :  1
Los Angeles Dodgers

Apr 20, 2026 - MLB

Colorado Rockies
3 :  12
Los Angeles Dodgers

Apr 19, 2026 - MLB

Colorado Rockies
9 :  6
Los Angeles Dodgers

Apr 18, 2026 - MLB

Colorado Rockies
4 :  3
Los Angeles Dodgers
Chicago Cubs
Chicago Cubs Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Apr 23, 2026 - MLB

Chicago Cubs
8 :  7
Philadelphia Phillies

Apr 22, 2026 - MLB

Chicago Cubs
7 :  2
Philadelphia Phillies

Apr 21, 2026 - MLB

Chicago Cubs
7 :  4
Philadelphia Phillies

Apr 20, 2026 - MLB

Chicago Cubs
5 :  1
Philadelphia Phillies

Apr 19, 2026 - MLB

Chicago Cubs
2 :  1
New York Mets

Apr 18, 2026 - MLB

Chicago Cubs
4 :  2
New York Mets
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Apr 23, 2026 - MLB

Chicago Cubs
8 :  7
Philadelphia Phillies

Apr 22, 2026 - MLB

Chicago Cubs
7 :  2
Philadelphia Phillies

Apr 21, 2026 - MLB

Chicago Cubs
7 :  4
Philadelphia Phillies

Apr 20, 2026 - MLB

Chicago Cubs
5 :  1
Philadelphia Phillies

Apr 19, 2026 - MLB

Chicago Cubs
2 :  1
New York Mets

Apr 18, 2026 - MLB

Chicago Cubs
4 :  2
New York Mets
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 15, 2026 - MLB

Philadelphia Phillies
2 :  11
Chicago Cubs

Apr 14, 2026 - MLB

Philadelphia Phillies
4 :  10
Chicago Cubs

Apr 13, 2026 - MLB

Philadelphia Phillies
13 :  7
Chicago Cubs

Apr 8, 2026 - MLB

Tampa Bay Rays
2 :  6
Chicago Cubs

Apr 7, 2026 - MLB

Tampa Bay Rays
2 :  9
Chicago Cubs

Apr 6, 2026 - MLB

Tampa Bay Rays
6 :  4
Chicago Cubs

Los Angeles Dodgers against Chicago Cubs : Head to Head (H2H)

Los Angeles Dodgers

17 %

Chicago Cubs

83 %

Mar 15, 2026 - MLB Spring Training

Chicago Cubs
8 :  14
Los Angeles Dodgers

Feb 28, 2026 - MLB Spring Training

Los Angeles Dodgers
2 :  6
Chicago Cubs

Apr 23, 2025 - MLB

Chicago Cubs
7 :  6
Los Angeles Dodgers

Apr 22, 2025 - MLB

Chicago Cubs
11 :  10
Los Angeles Dodgers

Apr 13, 2025 - MLB

Los Angeles Dodgers
2 :  4
Chicago Cubs

Apr 12, 2025 - MLB

Los Angeles Dodgers
0 :  16
Chicago Cubs

Los Angeles Dodgers - Chicago Cubs Key Points

  1. The total runs went over in the last four Chicago Cubs matches.
  2. The total runs went over 8.5 in the last four Chicago Cubs matches.
  3. The Cubs are 9-1 on the run line in their last 10 matches.
  4. The Cubs are 4-1 on the run line in their last five away games.

Our Los Angeles Dodgers vs Chicago Cubs Prediction

LA Dodgers are the -160 favorites in this evenly-matched contest. The first game delivered an open scoreline, and we expect this trend to continue. The Cubs should have enough talent to keep this game close, having defeated the Dodgers in six of their last seven meetings. The Dodgers, meanwhile, will want to bounce back with a statement win against one of their top challengers in the National League. LA’s Roki Sasaki will try to improve his 0-3, 6.11 ERA record this season. His opposite number, Colin Rea, has had a better outing for the Cubs, coming into this contest with a 3-0, 3.00 ERA record. He should help the Cubs compete and cover the +1.5 run line.

Our prediction for Los Angeles Dodgers vs Chicago Cubs: Over 8.5 runs.

Prediction:

 

Over 8.5 runs.

-159
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Los Angeles Dodgers vs Chicago Cubs Picks