Kansas City Royals vs Chicago Cubs Prediction & Picks - MLB

USA - MLB

Kansas City Royals
8/8/26 19:10
Chicago Cubs

Prediction:

 

Chicago Cubs ML

-171
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 by Matt Lowrimore in MLB Picks

A full 15-game MLB slate is scheduled for Saturday, one of which will feature an Interleague matchup between the Kansas City Royals and Chicago Cubs. Let’s take a look at the match statistics and predictions for this game between the Royals and the Cubs.

Chicago enters this game with one of the top records in the league and is currently in second place in the National League Central division. Starting this game for the Cubs will be Clay Holmes, who has a record of 4-4 and an ERA of 2.39. Holmes was recently traded to the Cubs, but with New York was at his best when pitching on the road, a trend that should continue against a poor Royals’ offense. 

As for Kansas City, they enter this game with one of the worst records in the league and are currently in last place in the American League Central Division. The Royals are set to start Seth Lugo in Game 2 of this series, who has a record of 4-7 and an ERA of 4.41.

Kansas City Royals vs Chicago Cubs Form

Table

Teams Pts P W L
5 Chicago Cubs
0.581 117 68 49
27 Kansas City Royals
0.41 117 48 69

Kansas City Royals and Chicago Cubs Latest Matches

Kansas City Royals
Kansas City Royals Latest matches
L L L W W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 6, 2026 - MLB

Kansas City Royals
3 :  4
Minnesota Twins

Aug 5, 2026 - MLB

Kansas City Royals
2 :  1
Minnesota Twins

Aug 4, 2026 - MLB

Kansas City Royals
8 :  2
Minnesota Twins

Aug 2, 2026 - MLB

Colorado Rockies
8 :  1
Kansas City Royals

Aug 1, 2026 - MLB

Colorado Rockies
12 :  6
Kansas City Royals

Jul 31, 2026 - MLB

Colorado Rockies
3 :  1
Kansas City Royals
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Aug 6, 2026 - MLB

Kansas City Royals
3 :  4
Minnesota Twins

Aug 5, 2026 - MLB

Kansas City Royals
2 :  1
Minnesota Twins

Aug 4, 2026 - MLB

Kansas City Royals
8 :  2
Minnesota Twins

Jul 22, 2026 - MLB

Kansas City Royals
5 :  4
San Francisco Giants

Jul 21, 2026 - MLB

Kansas City Royals
3 :  2
San Francisco Giants

Jul 20, 2026 - MLB

Kansas City Royals
4 :  3
San Francisco Giants
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Aug 2, 2026 - MLB

Colorado Rockies
8 :  1
Kansas City Royals

Aug 1, 2026 - MLB

Colorado Rockies
12 :  6
Kansas City Royals

Jul 31, 2026 - MLB

Colorado Rockies
3 :  1
Kansas City Royals

Jul 30, 2026 - MLB

Minnesota Twins
4 :  3
Kansas City Royals

Jul 29, 2026 - MLB

Minnesota Twins
0 :  4
Kansas City Royals

Jul 28, 2026 - MLB

Minnesota Twins
3 :  2
Kansas City Royals
Chicago Cubs
Chicago Cubs Latest matches
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Aug 6, 2026 - MLB

Chicago Cubs
3 :  2
Toronto Blue Jays

Aug 5, 2026 - MLB

Chicago Cubs
7 :  6
Los Angeles Dodgers

Aug 4, 2026 - MLB

Chicago Cubs
5 :  1
Los Angeles Dodgers

Aug 3, 2026 - MLB

Chicago Cubs
10 :  5
Los Angeles Dodgers

Aug 2, 2026 - MLB

Chicago Cubs
1 :  2
New York Yankees

Aug 1, 2026 - MLB

Chicago Cubs
5 :  2
New York Yankees
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Aug 6, 2026 - MLB

Chicago Cubs
3 :  2
Toronto Blue Jays

Aug 5, 2026 - MLB

Chicago Cubs
7 :  6
Los Angeles Dodgers

Aug 4, 2026 - MLB

Chicago Cubs
5 :  1
Los Angeles Dodgers

Aug 3, 2026 - MLB

Chicago Cubs
10 :  5
Los Angeles Dodgers

Aug 2, 2026 - MLB

Chicago Cubs
1 :  2
New York Yankees

Aug 1, 2026 - MLB

Chicago Cubs
5 :  2
New York Yankees
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 30, 2026 - MLB

St. Louis Cardinals
2 :  4
Chicago Cubs

Jul 29, 2026 - MLB

St. Louis Cardinals
3 :  2
Chicago Cubs

Jul 28, 2026 - MLB

St. Louis Cardinals
2 :  10
Chicago Cubs

Jul 27, 2026 - MLB

St. Louis Cardinals
3 :  7
Chicago Cubs

Jul 26, 2026 - MLB

Pittsburgh Pirates
8 :  7
Chicago Cubs

Jul 25, 2026 - MLB

Pittsburgh Pirates
0 :  11
Chicago Cubs

Kansas City Royals against Chicago Cubs : Head to Head (H2H)

Kansas City Royals

0 %

Chicago Cubs

100 %

Mar 11, 2026 - MLB Spring Training

Chicago Cubs
9 :  8
Kansas City Royals

Feb 23, 2026 - MLB Spring Training

Kansas City Royals
2 :  3
Chicago Cubs

Jul 22, 2025 - MLB

Chicago Cubs
6 :  0
Kansas City Royals

Aug 19, 2023 - MLB

Chicago Cubs
6 :  4
Kansas City Royals
Kansas City Royals vs Chicago Cubs Picks

Kansas City Royals - Chicago Cubs Key Points

  1. Clay Holmes has an ERA of 2.39 this season
  2. Clay Holmes has an ERA of 2.10 on the road this season
  3. Seth Lugo has an ERA of 4.41 this season
  4. Seth Lugo has an ERA of 3.63 at home this season

Our Kansas City Royals vs Chicago Cubs Prediction

The Cubs are the heavy favorite in this game; however, they still look to be the best betting option. Even though Holmes has not pitched since May (due to an injury) and is making his Cubs debut, he has simply been too strong.

Holmes has made five away starts this season, having allowed seven earned runs over 30.0 innings. As for Lugo, he has made 12 home starts this season, in which he has allowed 31 runs (28 earned) over 69.1 innings. 

While these are serviceable numbers for Lugo, the Cubs’ offense still looks too strong. For that reason, our Kansas City Royals vs Chicago Cubs prediction is: Chicago Cubs ML.

Prediction:

 

Chicago Cubs ML

-171
$150 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.