Houston Astros vs Chicago Cubs Prediction & Picks - MLB

USA - MLB

Houston Astros
6/29/25 14:10
Chicago Cubs

Prediction:

 

Under 7.5

-102
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 by Erik Gibbs | in MLB Picks

The Chicago Cubs and Houston Astros face off today in the rubber match of a three-game series at Daikin Park, with both clubs entering the contest at 49-34 on the season. Each team has claimed one victory in the series so far, setting up a pivotal showdown between two division leaders.

The Cubs dropped the opener 7-4 but bounced back with a resounding 12-3 win in game two. After falling behind 2-1 early, Chicago’s offense erupted, scoring 11 unanswered runs to cruise to victory. That offensive surge helped maintain their slim lead in the competitive NL Central.

The Cubs have found a bit of momentum in recent days, winning three of their last four games. Prior to arriving in Houston, they split a four-game set against division rival St. Louis and dropped two of three against the Mariners.

The Astros had their six-game win streak snapped in Saturday’s loss but remain in firm control of the AL West. Before this series, Houston swept the Phillies in three games and took two of three from the Angels. Their dominant home record of 31-14 has been a key factor in their success, and they’ll aim to add to that today with Framber Valdez on the mound.

Houston Astros vs Chicago Cubs Form

Table

Teams Pts P W L
6 Chicago Cubs
0.568 162 92 70
12 Houston Astros
0.537 162 87 75

Houston Astros and Chicago Cubs Latest Matches

Houston Astros
Houston Astros Latest matches
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jun 28, 2025 - MLB

Houston Astros
3 :  12
Chicago Cubs

Jun 27, 2025 - MLB

Houston Astros
7 :  4
Chicago Cubs

Jun 26, 2025 - MLB

Houston Astros
2 :  1
Philadelphia Phillies

Jun 25, 2025 - MLB

Houston Astros
2 :  0
Philadelphia Phillies

Jun 24, 2025 - MLB

Houston Astros
1 :  0
Philadelphia Phillies

Jun 22, 2025 - MLB

Los Angeles Angels
7 :  8
Houston Astros
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jun 28, 2025 - MLB

Houston Astros
3 :  12
Chicago Cubs

Jun 27, 2025 - MLB

Houston Astros
7 :  4
Chicago Cubs

Jun 26, 2025 - MLB

Houston Astros
2 :  1
Philadelphia Phillies

Jun 25, 2025 - MLB

Houston Astros
2 :  0
Philadelphia Phillies

Jun 24, 2025 - MLB

Houston Astros
1 :  0
Philadelphia Phillies

Jun 12, 2025 - MLB

Houston Astros
4 :  3
Chicago White Sox
L W L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 22, 2025 - MLB

Los Angeles Angels
7 :  8
Houston Astros

Jun 21, 2025 - MLB

Los Angeles Angels
9 :  1
Houston Astros

Jun 20, 2025 - MLB

Los Angeles Angels
2 :  3
Houston Astros

Jun 19, 2025 - MLB

Athletics
6 :  4
Houston Astros

Jun 18, 2025 - MLB

Athletics
4 :  11
Houston Astros

Jun 16, 2025 - MLB

Athletics
3 :  1
Houston Astros
Chicago Cubs
Chicago Cubs Latest matches
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 28, 2025 - MLB

Houston Astros
3 :  12
Chicago Cubs

Jun 27, 2025 - MLB

Houston Astros
7 :  4
Chicago Cubs

Jun 21, 2025 - MLB

Chicago Cubs
10 :  7
Seattle Mariners

Jun 20, 2025 - MLB

Chicago Cubs
4 :  9
Seattle Mariners

Jun 19, 2025 - MLB

Chicago Cubs
7 :  8
Milwaukee Brewers

Jun 14, 2025 - MLB

Chicago Cubs
2 :  1
Pittsburgh Pirates
W L W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 21, 2025 - MLB

Chicago Cubs
10 :  7
Seattle Mariners

Jun 20, 2025 - MLB

Chicago Cubs
4 :  9
Seattle Mariners

Jun 19, 2025 - MLB

Chicago Cubs
7 :  8
Milwaukee Brewers

Jun 14, 2025 - MLB

Chicago Cubs
2 :  1
Pittsburgh Pirates

Jun 13, 2025 - MLB

Chicago Cubs
1 :  2
Pittsburgh Pirates

Jun 12, 2025 - MLB

Chicago Cubs
3 :  2
Pittsburgh Pirates
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 28, 2025 - MLB

Houston Astros
3 :  12
Chicago Cubs

Jun 27, 2025 - MLB

Houston Astros
7 :  4
Chicago Cubs

Jun 7, 2025 - MLB

Detroit Tigers
1 :  6
Chicago Cubs

Jun 6, 2025 - MLB

Detroit Tigers
3 :  1
Chicago Cubs

May 24, 2025 - MLB

Cincinnati Reds
6 :  4
Chicago Cubs

May 21, 2025 - MLB

Miami Marlins
1 :  2
Chicago Cubs

Houston Astros against Chicago Cubs : Head to Head (H2H)

Houston Astros

25 %

Chicago Cubs

75 %

Jun 28, 2025 - MLB

Houston Astros
3 :  12
Chicago Cubs

Jun 27, 2025 - MLB

Houston Astros
7 :  4
Chicago Cubs

Apr 24, 2024 - MLB

Chicago Cubs
4 :  3
Houston Astros

Apr 23, 2024 - MLB

Chicago Cubs
7 :  2
Houston Astros

Houston Astros - Chicago Cubs Key Points

  1. The Astros are 8-0 in their last 8 games at Daikin Park following a home loss
  2. The Cubs are 0-4 in their last 4 games vs. American League teams following a win
  3. The Astros are 4-0 covering the run line in their last 4 games as favorites vs. NL Central teams after a loss
  4. The Cubs are 0-6 covering the run line in their last 6 games as road underdogs after a win.

Our Houston Astros vs Chicago Cubs Prediction

Despite some inconsistency, Chicago remains atop the NL Central, thanks in part to their solid road performance. They carry a 24-19 record away from Wrigley Field into today’s game, and they'll look to keep that success going behind starter Jameson Taillon.

Taillon enters the game with a 7-5 record and a 4.47 ERA across 90.2 innings. However, recent outings have not been kind to him — he’s surrendered 13 earned runs and 16 hits over just eight innings in his last two starts combined. Chicago will need Taillon to rebound if they hope to secure a series win against a red-hot Houston team.

Valdez has been outstanding this season, boasting an 8-4 record with a 2.88 ERA and 1.13 WHIP over 103 innings. He’s been especially dominant lately, allowing two earned runs or fewer in five consecutive starts. Valdez’s form, combined with the Astros’ home-field advantage, gives Houston a strong chance to bounce back and take the series.

With both teams eyeing postseason contention, today’s matchup could carry weight beyond the regular season. It's a battle of strength versus momentum, with two of MLB’s best squaring off in what promises to be a compelling finale. Our prediction for Houston Astros vs. Chicago Cubs: Astros to win.

Prediction:

 

Under 7.5

-102
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Houston Astros vs Chicago Cubs Picks