Cincinnati Reds vs Chicago Cubs Prediction & Picks - MLB
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by Travis Pulver | in MLB Picks
The Chicago Cubs (52-42, 25-23 Away) will try to get back on the right side of the scoreboard today when they face the Cincinnati Reds at Great America Ball Park. First Pitch for this contest is scheduled for 7:10 p.m. EST with coverage provided by ESPN Unlimited.
Chicago’s lineup went quiet last night as the Reds kept them off the scoreboard in a 4-0 win. It was the second loss in a row for the Cubs and the second time in the last six games that they were shut out.
Javier Assad will do his part to get the Cubbies back on track when he takes the mound to start the day. Assad is 6-1 in seven starts and 14 appearances this season with a 4.15 ERA and a 1.10 WHIP. However, he has not been at his best away from home (5.90 ERA and a .277 OBA) despite a 4-1 record in seven appearances (four starts).
Nick Lodolo is scheduled to get the start for the Reds. He has gone 3-2 in 11 starts with a 4.68 ERA and a 1.46 WHIP. He has not been at his best at home, where he is 2-2 with a 5.50 ERA and a .288 OBA.
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Cincinnati Reds vs Chicago Cubs Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
5
|
0.58 | 119 | 69 | 50 |
|
21
|
0.479 | 117 | 56 | 61 |
Cincinnati Reds and Chicago Cubs Latest Matches
3/6 (50%)
3/6 (50%)
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3/6 (50%)
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2/6 (33%)
4/6 (67%)
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3/6 (50%)
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4/6 (67%)
2/6 (33%)
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4/6 (67%)
2/6 (33%)
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Cincinnati Reds against Chicago Cubs : Head to Head (H2H)
33 %
67 %
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Mar 20, 2026 - MLB Spring Training
Cincinnati Reds - Chicago Cubs Key Points
- The Cubs lead the Reds in the all-time series, 1217-1195-22.
- Chicago is 23-25 ATS (run line) on the road; the Reds are 24-24 ATS (run line) at home.
- The OVER is 25-22-1 for the Cubs on the road and 26-22 for the Reds at home.
- Betting Public: 44% of total tickets and 34% of the handle is on the UNDER.
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Our Cincinnati Reds vs Chicago Cubs Prediction
Neither pitcher is in a place where he has typically thrown well this season, which is probably why the public is going with the OVER for this game. But while that is a valid point, I’m not confident either lineup can take advantage of the situation. The Cubs have hit .233 over the last week, and the Reds .230, with both averaging right around 4 runs per game. I’d lean towards the Cubs ML if you want a winner, but the total is a much better bet for this game.
Our Cubs vs. Reds Pick: UNDER 10
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